A column-switching LC/MS/ESI method for detecting tetrodotoxin and Aconitum alkaloids in serum

Legal Medicine

Volumn 5, Issue SUPPL. 1, 2003, Pages

  Hayashida, Makiko ^a   Hayakawa, Hideyuki ^a   Wada, Kentaro ^a   Yamada, Takeshi ^a   Nihira, Makoto ^a   Ohno, Youkichi ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Aconitine; Column switching; Liquid chromatography mass spectrometry electrospray ionization; Tetrodotoxin

Indexed keywords

14 ANISOYLACONINE; ACONITINE; ACONITUM EXTRACT; BENZOYLACONINE; BENZOYLHYPACONINE; BENZOYLMESACONINE; HYPACONITINE; JESACONITINE; MESACONITINE; TETRODOTOXIN; UNCLASSIFIED DRUG;

BLOOD SAMPLING; CALIBRATION; CATION EXCHANGE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG DETERMINATION; HUMAN; HUMAN EXPERIMENT; ION MONITORING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NORMAL HUMAN; SEPARATION TECHNIQUE; TOXIN ANALYSIS;

EID: 0038077565     PISSN: 13446223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1344-6223(02)00076-7     Document Type: Conference Paper

References (3)

1. Ohno Y. The experimental approach to the murder case of aconite poisoning. J Toxicol Toxin Rev 1998;17:1-11.
2. Rittner M, Pragst F, Bork WR, Neumann J. Screening method of seventy psychoactive drug or drug metabolites in serum based on high-performance liquid chromatography-electrospray ionization mass spectrometry. J Anal Toxicol 2001;25:115-124.
3. Hermansson J, Grahn A. Determination of direct injection of plasma into a biocompatible extraction column based on a protein-entrapped hydrophobic phase. J Chromatogr A 1994;660:119-129.