Results with early follicular phase recombinant luteinizing hormone supplementation during stimulation for in vitro fertilization

Fertility and Sterility

Volumn 93, Issue 2, 2010, Pages 475-479

  Kovacs, Peter ^a   Kovats, Timea ^a   Kaali, Steven G ^a  

^a IVF Center   (Hungary)

Author keywords

expense; IVF; ovarian stimulation; pregnancy rate; Recombinant LH

Indexed keywords

BUSERELIN; GONADORELIN AGONIST; RECOMBINANT CHORIONIC GONADOTROPIN; RECOMBINANT FOLLITROPIN; RECOMBINANT LUTEINIZING HORMONE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; FERTILIZATION IN VITRO; FOLLICULAR PHASE; HUMAN; OVARY FUNCTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ADULT; EMBRYO TRANSFER; ESTRADIOL; FEMALE; FERTILIZATION IN VITRO; FOLLICLE STIMULATING HORMONE; FOLLICULAR PHASE; GONADOTROPINS; HUMANS; LUTEINIZING HORMONE; MENSTRUAL CYCLE; OOCYTES; OVULATION INDUCTION; PREGNANCY; PROGESTERONE; RECOMBINANT PROTEINS; REFERENCE VALUES;

EID: 74449087919     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2008.12.010     Document Type: Article

References (28)

1. Gougeon A. Regulation of ovarian follicular development in primates: facts and hypotheses. Endocr Rev 17 (1996) 121-155
2. Fevold H.L. Synergism of follicle stimulating and luteinizing hormones in producing estrogen secretion. Endocrinology 28 (1941) 33-36
3. Hillier S.G. Gonadotropic control of ovarian follicular growth and development. Mol Cell Endocrinol 179 (2001) 39-46
4. Filicori M., Cognigni G.E., Samara A., Melappioni S., Perri T., Cantelli B., et al. The use of LH activity to drive folliculogenesis: exploring uncharted territories in ovulation induction. Hum Reprod Update 8 (2002) 543-557
5. Vendola K.A., Zhou J., Adesanya O.O., Weil S.J., and Bondy C.A. Androgens stimulate early stages of follicular growth in the primate ovary. J Clin Invest 101 (1998) 2622-2629
6. Weil S., Vendola K., Zhou J., and Bondy C.A. Androgen and follicle-stimulating hormone interactions in primate ovarian follicle development. J Clin Endocrinol Metab 84 (1999) 2951-2957
7. Barad D.H., and Gleicher N. Increased oocyte production after treatment with dehydroepiandrosterone. Fertil Steril 84 (2005) 756
8. Barad D., and Gleicher N. Effect of dehydroepiandrosterone on oocyte and embryo yields, embryo grade and cell number in IVF. Hum Reprod 21 (2006) 2845-2849
9. Garcia-Velasco J.A., Moreno L., Pacheco A., Guillén A., Duque L., Requena A., et al. The aromatase inhibitor letrozole increases the concentration of intraovarian androgens and improves in vitro fertilization outcome in low responder patients: a pilot study. Fertil Steril 84 (2005) 82-87
10. Lossl K., Andersen A.N., Loft A., Freiesleben N.L., Bangsbøll S., and Andersen C.Y. Androgen priming using aromatase inhibitor and hCG during early-follicular-phase GnRH antagonist down-regulation in modified antagonist protocols. Hum Reprod 21 (2006) 2593-2600
11. Lossl K., Andersen C.Y., Loft A., Freiesleben N.L., Bangsbøll S., and Andersen A.N. Short-term androgen priming by use of aromatase inhibitor and hCG before controlled ovarian stimulation for IVF. A randomized controlled trial. Hum Reprod (2008 May 15) [Epub ahead of print]
12. Practice Committee of the Society for Assisted Reproductive Technology; Practice Committee of the American Society for Reproductive Medicine. Guidelines on number of embryos transferred. Fertil Steril 86 5 Suppl (2006) S51-S52
13. Shoham Z., Mannaerts B., Insler V., and Coelingh-Bennink H. Induction of follicular growth using recombinant human follicle-stimulating hormone in two volunteer women with hypogonadotropic hypogonadism. Fertil Steril 59 (1993) 738-742
14. Karnitis V.J., Townson D.H., Friedman C.I., and Danforth D.R. Recombinant human follicle-stimulating hormone stimulates multiple follicular growth, but minimal estrogen production in gonadotropin-releasing hormone antagonist-treated monkeys: examining the role of luteinizing hormone in follicular development and steroidogenesis. J Clin Endocrinol Metab 79 (1994) 91-97
15. The European Recombinant Human LH Study Group. Recombinant human luteinizing hormone (LH) to support recombinant human follicle-stimulating hormone (FSH)-induced follicular development in LH- and FSH-deficient anovulatory women: a dose-finding study. The European Recombinant Human LH Study Group. J Clin Endocrinol Metab 83 (1998) 1507-1514
16. Shoham Z. The clinical therapeutic window for luteinizing hormone in controlled ovarian stimulation. Fertil Steril 77 (2002) 1170-1177
17. Lahoud R., Al-Jefout M., Tyler J., Ryan J., and Driscoll G. A relative reduction in mid-follicular LH concentrations during GnRH agonist IVF/ICSI cycles leads to lower live birth rates. Hum Reprod 21 (2006) 2645-2649
18. Bosch E., Escudero E., Crespo J., Simón C., Remohí J., and Pellicer A. Serum luteinizing hormone in patients undergoing ovarian stimulation with gonadotropin-releasing hormone antagonists and recombinant follicle-stimulating hormone and its relationship with cycle outcome. Fertil Steril 84 (2005) 1529-1532
19. Merviel P., Antoine J.M., Mathieu E., Millot F., Mandelbaum J., and Uzan S. Luteinizing hormone concentrations after gonadotropin-releasing hormone antagonist administration do not influence pregnancy rates in in vitro fertilization-embryo transfer. Fertil Steril 82 (2004) 119-125
20. Fleming R., Chung C.C., Yates R.W., and Coutts J.R. Purified urinary follicle stimulating hormone induces different hormone profiles compared with menotrophins, dependent upon the route of administration and endogenous luteinizing hormone activity. Hum Reprod 11 (1996) 1854-1858
21. Westergaard L.G., Erb K., Laursen S., Rasmussen P.E., and Rex S. The effect of human menopausal gonadotrophin and highly purified, urine-derived follicle stimulating hormone on the outcome of in-vitro fertilization in down-regulated normogonadotrophic women. Hum Reprod 11 (1996) 1209-1213
22. Kolibianakis E.M., Kalogeropoulou L., Griesinger G., Papanikolaou E.G., Papadimas J., Bontis J., et al. Among patients treated with FSH and GnRH analogues for in vitro fertilization, is the addition of recombinant LH associated with the probability of live birth? A systematic review and meta-analysis. Hum Reprod Update 13 (2007) 445-452
23. Barrenetxea G., Agirregoikoa J.A., Jiménez M.R., de Larruzea A.L., Ganzabal T., and Carbonero K. Ovarian response and pregnancy outcome in poor-responder women: a randomized controlled trial on the effect of luteinizing hormone supplementation on in vitro fertilization cycles. Fertil Steril 89 (2008) 546-553
24. Tarlatzis B., Tavmergen E., Szamatowicz M., Barash A., Amit A., Levitas E., et al. The use of recombinant human LH (lutropin alfa) in the late stimulation phase of assisted reproduction cycles: a double-blind, randomized, prospective study. Hum Reprod 21 (2006) 90-94
25. De Placido G., Alviggi C., Perino A., Strina I., Lisi F., Fasolino A., et al. Italian Collaborative Group on Recombinant Human Luteinizing Hormone. Recombinant human LH supplementation versus recombinant human FSH (rFSH) step-up protocol during controlled ovarian stimulation in normogonadotrophic women with initial inadequate ovarian response to rFSH. A multicentre, prospective, randomized controlled trial. Hum Reprod 20 (2005) 390-396
26. Tesarik J., and Mendoza C. Effects of exogenous LH administration during ovarian stimulation of pituitary down-regulated young oocyte donors on oocyte yield and developmental competence. Hum Reprod 17 (2002) 3129-3137
27. Humaidan P., Bungum M., Bungum L., and Andersen C.Y. Effects of recombinant LH supplementation in women undergoing assisted reproduction with GnRH agonist down-regulation and stimulation with recombinant FSH: an opening study. Reprod Biomed Online 8 (2004) 635-643
28. Durnerin C.I., Erb K., Fleming R., Hillier H., Hillier S.G., Howles C.M., et al. Luveris Pretreatment Group. Effects of recombinant LH treatment on folliculogenesis and responsiveness to FSH stimulation. Hum Reprod 23 (2008) 421-426