An improved formal total synthesis of (-)-anisomycin

Arkivoc

Volumn 2003, Issue 2, 2003, Pages 7-14

  Huang, Pei Qiang ^a   Zheng, Xiao ^a  

^a XIAMEN UNIVERSITY   (China)

Author keywords

Anisomycin; Asymmetric Synthesis; Malic Acid; Malimide; Reductive alkylation

Indexed keywords

1 BENZYLOXYCARBONYL 2 (4 METHOXYPHENYL)METHYL 3 PYRROLINE; ANISOMYCIN; MALEIMIDE DERIVATIVE; N,O DIBENZYLMALEIMIDE; PYRROLINE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; ASYMMETRIC SYNTHESIS; DRUG SYNTHESIS; REDUCTION; STEREOCHEMISTRY;

EID: 7444261754     PISSN: 14246376     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Sobin, B. A.; Tanner, F. W., Jr. J. Am Chem. Soc. 1954, 76, 4053.
2. Jimenez, A.; Vazquez, D. in Antibiotics, ed, F. E. Hahn, Springer Verlag, Berlin, 1979, pp. 1-19; For a recent example, see: Dudai, Y. Nature 2000, 406, 686; Nader, K.; Schafe, G. E.; Le Doux, J. E. Nature 2000, 406, 722.
3. Jimenez, A.; Vazquez, D. in Antibiotics, ed, F. E. Hahn, Springer Verlag, Berlin, 1979, pp. 1-19; For a recent example, see: Dudai, Y. Nature 2000, 406, 686; Nader, K.; Schafe, G. E.; Le Doux, J. E. Nature 2000, 406, 722.
4. Jimenez, A.; Vazquez, D. in Antibiotics, ed, F. E. Hahn, Springer Verlag, Berlin, 1979, pp. 1-19; For a recent example, see: Dudai, Y. Nature 2000, 406, 686; Nader, K.; Schafe, G. E.; Le Doux, J. E. Nature 2000, 406, 722.
5. Frye, W. W.; Mule, J. G.; Swartzwelder, C. Antibiot. Annu., 1954-1955, 820.
6. Korzybsky, T.; Kowszyk-Gindifer, Z.; Kurgtowicz, W. in Antibiotics, American Society of Microbiology, Washington DC, 1978, pp. 343-346.
7. The Merck Index, 12th ed., Windholz, M., Ed., Merck: Whitehouse Station, NJ, 1996, p 710.
8. Hosoya, Y.; Kameyama, T.; Naganawa, H.; Okami, Y.; Takeuchi, T. J. Antibiot. 1993, 46, 1300.
9. (a) Van der Bosch, J.; Rueller, S.; Schlaak, M. German Patent DE 19,744,676, 1999; Chem. Abstr. 1999, 130, 291581. (b) Rueller, S.; Stahl, C.; Kohler, G; Eickhoff, B.; Breder, J.; Schlaak, M.; van der Bosch, J. Clin. Cancer Res. 1999, 5, 2714.
10. (a) Van der Bosch, J.; Rueller, S.; Schlaak, M. German Patent DE 19,744,676, 1999; Chem. Abstr. 1999, 130, 291581. (b) Rueller, S.; Stahl, C.; Kohler, G; Eickhoff, B.; Breder, J.; Schlaak, M.; van der Bosch, J. Clin. Cancer Res. 1999, 5, 2714.
11. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
12. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
13. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
14. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
15. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
16. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
17. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
18. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
19. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
20. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
21. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
22. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
23. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
24. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
25. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
26. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
27. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
28. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
29. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
30. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
31. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
32. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
33. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
34. (a) Wong, C. M.; Bucchini, J.; Chang, I.; Te Raa, J.; Schenk, R. Can. J. Chem. 1969, 47, 2421. (b) Oida, S.; Ohki, E. Chem. Pharm. Bull. 1969, 17, 1405. (c) Felner, I.; Schenker, E. Helv. Chim. Acta 1970, 53, 754. (d) Verheyden, J. P. H.; Richardson, A. C.; Bhatt, R. S.; Grant, B. D.; Flitch, W. L.; Moffat, J. G. Pure Appl. Chem. 1978, 50, 1363. (e) Schumacher, D. P.; Hall, S. S. J. Am. Chem. Soc. 1982, 104, 6076. (f) Buchanan, J. G.; MacLean, K. A.; Wightman, R. H.; Paulsen, H. J. Chem. Soc., Perkin Trans. 1 1985, 486. (g) Iida, H.; Yamazaki, N.; Kibayashi, C. J. Org. Chem. 1986, 51, 1069. (h) Meyers, A. I.; Dupre, B. Heterocycles 1987, 25, 113. (i) Shono, T.; Kise, N. Chem. Lett. 1987, 697. (j) Baer, H. H.; Zamkanei, M. J. Org. Chem. 1988, 53, 4786. (k) Jegham, S.; Das, B. C. Tetrahedron Lett. 1988, 29, 4419. (l) Takano, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1861. (m) Takahata, H.; Banba, Y.; Tajima, M.; Momose, T. J. Org. Chem. 1991, 56, 240. (n) Ballini, R.; Marcantoni, E.; Petrini, M. J. Org. Chem. 1992, 57, 1316. (o) Ikota, N. Heterocycles 1995, 41, 983. (p) Yoda, H.; Nakajima, T.; Yamazaki, H.; Takabe, K. Heterocycles 1995, 41, 2423. (q) Shi, Z.-C.; Lin, G.-Q. Tetrahedron: Asymmetry 1995, 6, 2907. (r) Kang, S. H.; Choi, H.-W. Chem. Commun. 1996, 1521. (s) Han, G.; LaPorte, M. G.; McIntosh, M. C.; Weinreb, S. M.; Parvez, M. J. Org. Chem. 1996, 61, 9483. (t) Veith, U.; Schwardt, O.; Jaget, V. Synlett 1996, 1181. (u) Delair, P.; Brot, E.; Kanazawa, A.; Greene, A. E. J. Org. Chem. 1999, 64, 1383. (v) Schwartdt, O.; Veith, U.; Gaspard, C.; Jager, V. Synthesis 1999, 1473. (w) Hutin, P.; Haddad, M.; Larcheveque, M. Tetrahedron: Asymmetry 2000, 11, 2547. (x) Hulme, A.N.; Rosser, E.M. Org. Lett. 2002, 4, 265.
35. (a) Huang, P.-Q.; Chen, Q.-F.; Chen, C.-L.; Zhang, H.-K. Tetrahedron: Asymmetry 1999, 10, 3827. (b) Huang, P.-Q.; Wang, S.-L.; Ye, J.-L.; Ruan, Y.-P.; Huang, Y.-Q.; Zheng, H. Tetrahedron 1998, 54, 12547. (c) Huang, P.-Q.; Ye, J.-L.; Chen, Z.; Ruan, Y.-P. Synthetic Commun. 1998, 28, 417. (d) Huang, P.-Q.; Wang, S.-L.; Zheng, H.; Fei, X.-S. Tetrahedron Lett. 1997, 38, 271.
36. (a) Huang, P.-Q.; Chen, Q.-F.; Chen, C.-L.; Zhang, H.-K. Tetrahedron: Asymmetry 1999, 10, 3827. (b) Huang, P.-Q.; Wang, S.-L.; Ye, J.-L.; Ruan, Y.-P.; Huang, Y.-Q.; Zheng, H. Tetrahedron 1998, 54, 12547. (c) Huang, P.-Q.; Ye, J.-L.; Chen, Z.; Ruan, Y.-P. Synthetic Commun. 1998, 28, 417. (d) Huang, P.-Q.; Wang, S.-L.; Zheng, H.; Fei, X.-S. Tetrahedron Lett. 1997, 38, 271.
37. (a) Huang, P.-Q.; Chen, Q.-F.; Chen, C.-L.; Zhang, H.-K. Tetrahedron: Asymmetry 1999, 10, 3827. (b) Huang, P.-Q.; Wang, S.-L.; Ye, J.-L.; Ruan, Y.-P.; Huang, Y.-Q.; Zheng, H. Tetrahedron 1998, 54, 12547. (c) Huang, P.-Q.; Ye, J.-L.; Chen, Z.; Ruan, Y.-P. Synthetic Commun. 1998, 28, 417. (d) Huang, P.-Q.; Wang, S.-L.; Zheng, H.; Fei, X.-S. Tetrahedron Lett. 1997, 38, 271.
38. (a) Huang, P.-Q.; Chen, Q.-F.; Chen, C.-L.; Zhang, H.-K. Tetrahedron: Asymmetry 1999, 10, 3827. (b) Huang, P.-Q.; Wang, S.-L.; Ye, J.-L.; Ruan, Y.-P.; Huang, Y.-Q.; Zheng, H. Tetrahedron 1998, 54, 12547. (c) Huang, P.-Q.; Ye, J.-L.; Chen, Z.; Ruan, Y.-P. Synthetic Commun. 1998, 28, 417. (d) Huang, P.-Q.; Wang, S.-L.; Zheng, H.; Fei, X.-S. Tetrahedron Lett. 1997, 38, 271.
39. Huang, P. Q.; Wang, S. L.; Ruan, Y. P.; Gao, J. X. Nat. Prod. Lett. 1998, 11, 101. In this communication the regioselectivity in the Grignard reagent addition to malimide 4 should be corrected as 80:20, see, Huang, P.-Q.; Wang, S.-L.; Ruan, Y.-P.; Gao, J.-X. corrigendum submitted to Nat. Prod. Lett.
40. Huang, P. Q.; Wang, S. L.; Ruan, Y. P.; Gao, J. X. Nat. Prod. Lett. 1998, 11, 101. In this communication the regioselectivity in the Grignard reagent addition to malimide 4 should be corrected as 80:20, see, Huang, P.-Q.; Wang, S.-L.; Ruan, Y.-P.; Gao, J.-X. corrigendum submitted to Nat. Prod. Lett.
41. (a) Kursanov, D. N.; Parnes, Z. N.; Loim, N. M. Synthesis 1974, 633. (b) Hart, D. J.; Yang, T.-K. J. Org. Chem. 1985, 50, 235. (c) Rolf, D.; Gray, G. R. J. Am. Chem. Soc. 1982, 104, 3539. (d) Burgess, L. E.; Meyers, A. I. J. Org. Chem. 1992, 57, 1656. (e) Yoda, H.; Kitayama, H.; Yamade, W.; Katagiri, T.; Takabe, K.; Tetrahedron: Asymmetry, 1993, 4, 1451.
42. (a) Kursanov, D. N.; Parnes, Z. N.; Loim, N. M. Synthesis 1974, 633. (b) Hart, D. J.; Yang, T.-K. J. Org. Chem. 1985, 50, 235. (c) Rolf, D.; Gray, G. R. J. Am. Chem. Soc. 1982, 104, 3539. (d) Burgess, L. E.; Meyers, A. I. J. Org. Chem. 1992, 57, 1656. (e) Yoda, H.; Kitayama, H.; Yamade, W.; Katagiri, T.; Takabe, K.; Tetrahedron: Asymmetry, 1993, 4, 1451.
43. (a) Kursanov, D. N.; Parnes, Z. N.; Loim, N. M. Synthesis 1974, 633. (b) Hart, D. J.; Yang, T.-K. J. Org. Chem. 1985, 50, 235. (c) Rolf, D.; Gray, G. R. J. Am. Chem. Soc. 1982, 104, 3539. (d) Burgess, L. E.; Meyers, A. I. J. Org. Chem. 1992, 57, 1656. (e) Yoda, H.; Kitayama, H.; Yamade, W.; Katagiri, T.; Takabe, K.; Tetrahedron: Asymmetry, 1993, 4, 1451.
44. (a) Kursanov, D. N.; Parnes, Z. N.; Loim, N. M. Synthesis 1974, 633. (b) Hart, D. J.; Yang, T.-K. J. Org. Chem. 1985, 50, 235. (c) Rolf, D.; Gray, G. R. J. Am. Chem. Soc. 1982, 104, 3539. (d) Burgess, L. E.; Meyers, A. I. J. Org. Chem. 1992, 57, 1656. (e) Yoda, H.; Kitayama, H.; Yamade, W.; Katagiri, T.; Takabe, K.; Tetrahedron: Asymmetry, 1993, 4, 1451.
45. (a) Kursanov, D. N.; Parnes, Z. N.; Loim, N. M. Synthesis 1974, 633. (b) Hart, D. J.; Yang, T.-K. J. Org. Chem. 1985, 50, 235. (c) Rolf, D.; Gray, G. R. J. Am. Chem. Soc. 1982, 104, 3539. (d) Burgess, L. E.; Meyers, A. I. J. Org. Chem. 1992, 57, 1656. (e) Yoda, H.; Kitayama, H.; Yamade, W.; Katagiri, T.; Takabe, K.; Tetrahedron: Asymmetry, 1993, 4, 1451.
46. For reviews on the N-acyliminium chemistry, see, (a). Speckamp, W. N.; Hiemstra, H. Tetrahedron 1985, 41, 4367. (b). Speckamp, W. N.; Moolenaar, M. J. Tetrahedron 2000, 56, 3817.
47. For reviews on the N-acyliminium chemistry, see, (a). Speckamp, W. N.; Hiemstra, H. Tetrahedron 1985, 41, 4367. (b). Speckamp, W. N.; Moolenaar, M. J. Tetrahedron 2000, 56, 3817.