Carboxylic acid and phosphate ester derivatives of fluconazole: Synthesis and antifungal activities

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 23, 2004, Pages 6255-6269

  Nam, Nguyen Hai ^a   Sardari, Soroush ^a   Selecky, Meredith ^a   Parang, Keykavous ^a  

^a UNIVERSITY OF RHODE ISLAND   (United States)

Author keywords

Antifungal activity; Carboxylic acid esters; Phosphate esters; Synthesis

Indexed keywords

11 BROMOUNDECANYL 2 CYANOETHYLFLUCONAZOLE PHOSPHATE; 11 BROMOUNDECANYLFLUCONAZOLE PHOSPHATE; 2 CYANOETHYL N OCTYLFLUCONAZOLE PHOSPHATE; 2 CYANOETHYL N UNDECANYLFLUCONAZOLE PHOSPHATE; 2 CYANOETHYL OMEGA UNDECYLENYLFLUCONAZOLE PHOSPHATE; 2 CYANOETHYL[1 (BETA DEXTRO 2,3,4,6 GLUCOSYLTETRAACETATE)]FLUCONAZOLE PHOSPHATE; 2 CYANOETHYLTETRADECANYLFLUCONAZOLE PHOSPHATE; ANTIFUNGAL AGENT; CARBOXYLIC ACID DERIVATIVE; ESTER DERIVATIVE; FLUCONAZOLE; METHYL N OCTYLFLUCONAZOLE PHOSPHATE; METHYL OMEGA UNDECYLENYLFLUCONAZOLE PHOSPHATE; METHYLUNDECANYLFLUCONAZOLE PHOSPHATE; N TETRADECANYLFLUCONAZOLE PHOSPHATE; N UNDECANYLFLUCONAZOLE PHOSPHATE; O 11 BROMOUNDECANOYLFLUCONAZOLE; O 2 BROMOBUTYRYLFLUCONAZOLE; O 2 BROMOHEXANOYLFLUCONAZOLE; O 2 BROMOLAUROYLFLUCONAZOLE; O 2 BROMOMYRISTOYLFLUCONAZOLE; O 2 BROMOOCTANOYLFLUCONAZOLE; O 2 BROMOPROPIONYLFLUCONAZOLE; O 2 BROMOVALEROYLFLUCONAZOLE; O 2 CHLOROETHYLOXYCARBONYLFLUCONAZOLE; O ACETYLFLUCONAZOLE; O SALICYLFLUCONAZOLE; O TETRADECANOYLFLUCONAZOLE; OMEGA UNDECYLENYLFLUCONAZOLE PHOSPHATE; PHOSPHATE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; CANDIDA ALBICANS; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; LIPOPHILICITY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; SKIN PERMEABILITY;

ANTIFUNGAL AGENTS; ASPERGILLUS NIGER; CANDIDA ALBICANS; CARBOXYLIC ACIDS; CRYPTOCOCCUS NEOFORMANS; FLUCONAZOLE; MICROBIAL SENSITIVITY TESTS; PHOSPHORIC ACID ESTERS; STRUCTURE-ACTIVITY RELATIONSHIP;

ASPERGILLUS; ASPERGILLUS NIGER; CANDIDA; CANDIDA ALBICANS; FILOBASIDIELLA NEOFORMANS;

EID: 7444249091     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.08.049     Document Type: Article

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