Anemia and impaired stress-induced erythropoiesis in aceruloplasminemic mice

Blood Cells, Molecules, and Diseases

Volumn 33, Issue 3, 2004, Pages 346-355

  Cherukuri, Srujana ^a,b   Tripoulas, Nicholas A ^a   Nurko, Saul ^a   Fox, Paul L ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CLEVELAND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERULOPLASMIN; FERRITIN; HEMOGLOBIN; IRON; PHENYLHYDRAZINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD ANALYSIS; CELL SURVIVAL; CERULOPLASMIN BLOOD LEVEL; CONTROLLED STUDY; ERYTHROCYTE COUNT; ERYTHROPOIESIS; HALF LIFE TIME; HEMATOCRIT; HEMOLYTIC ANEMIA; IRON BLOOD LEVEL; IRON DEFICIENCY ANEMIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RETICULOCYTE COUNT; STRESS;

ANEMIA, HYPOCHROMIC; ANIMALS; CERULOPLASMIN; ERYTHROPOIESIS; HUMANS; IRON; MICE; MICE, KNOCKOUT; OXIDANTS; PHENYLHYDRAZINES; RETICULOCYTES; TRANSFERRIN;

EID: 7444243833     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2004.07.003     Document Type: Article

References (44)

1. G.M. Brittenham Disorders of iron metabolism: iron deficiency and overload R. Hoffman E.J. Benz S.J. Shattil B. Furie H.J. Cohen L.E. Silberstien P. McGlave Hematology: Basic Principles Practice 2000 Harcourt New York 397 428
2. E.B. Hart, H. Steenbock, J. Waddell, and C.A. Elvehjem Iron in nutrition: VII. Copper as a supplement to iron for hemoglobin building in the rat J. Biol. Chem. 77 1928 797 812
3. J.S. McHargue, D.J. Healy, and E.S. Hill The relation of copper to the hemoglobin content of rat blood J. Biol. Chem. 78 1928 637 641
4. G.E. Cartwright, C.J. Gubler, J.A. Bush, and M.M. Wintrobe Studies on copper metabolism: XVII. Further observations on the anemia of copper deficiency in swine Blood 11 1956 143 153
5. S. Osaki, D.A. Johnson, and E. Frieden The mobilization of iron from the perfused mammalian liver by a serum copper enzyme, ferroxidase I J. Biol. Chem. 246 1971 3018 3023
6. J. Sarkar, V. Seshadri, N.A. Tripoulas, M.E. Ketterer, and P.L. Fox Role of ceruloplasmin in macrophage iron efflux during hypoxia J. Biol. Chem. 278 2003 44018 44024
7. C. Askwith, D. Eide, A. Van Ho, P.S. Bernard, L. Li, S. Davis-Kaplan, D.M. Sipe, and J. Kaplan The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake Cell 76 1994 403 410
8. A. Dancis, D.S. Yuan, D. Haile, C. Askwith, D. Eide, C. Moehle, J. Kaplan, and R.D. Klausner Molecular characterization of a copper transport protein in S. cerevisiae: an unexpected role for copper in iron transport Cell 76 1994 393 402
9. H. Morita, S. Ikeda, K. Yamamoto, S. Morita, K. Yoshida, S. Nomoto, M. Kato, and N. Yanagisawa Hereditary ceruloplasmin deficiency with hemosiderosis: a clinicopathological study of a Japanese family Ann. Neurol. 37 1995 646 656
10. Z.L. Harris, L.W. Klomp, and J.D. Gitlin Aceruloplasminemia: an inherited neurodegenerative disease with impairment of iron homeostasis Am. J. Clin. Nutr. 67 1998 972S 977S
11. K. Yamaguchi, S. Takahashi, T. Kawanami, T. Kato, and H. Sasaki Retinal degeneration in hereditary ceruloplasmin deficiency Ophthalmologica 212 1998 11 14
12. H. Miyajima, S. Kohno, Y. Takahashi, O. Yonekawa, and T. Kanno Estimation of the gene frequency of aceruloplasminemia in Japan Neurology 53 1999 617 619
13. N.E. Hellman, M. Schaefer, S. Gehrke, P. Stegen, W.J. Hoffman, J.D. Gitlin, and W. Stremmel Hepatic iron overload in aceruloplasminaemia Gut 47 2000 858 860
14. S. Bosio, M. De Gobbi, A. Roetto, G. Zecchina, E. Leonardo, M. Rizzetto, C. Lucetti, L. Petrozzi, U. Bonuccelli, and C. Camaschella Anemia and iron overload due to compound heterozygosity for novel ceruloplasmin mutations Blood 100 2002 2246 2248
15. K. Yamamoto, K. Yoshida, Y. Miyagoe, A. Ishikawa, K. Hanaoka, S. Nomoto, K. Kaneko, S. Ikeda, and S. Takeda Quantitative evaluation of expression of iron-metabolism genes in ceruloplasmin-deficient mice Biochim. Biophys. Acta 1588 2002 195 202
16. B.N. Patel, R.J. Dunn, S.Y. Jeong, Q. Zhu, J.P. Julien, and S. David Ceruloplasmin regulates iron levels in the CNS and prevents free radical injury J. Neurosci. 22 2002 6578 6586
17. Z.L. Harris, A.P. Durley, T.K. Man, and J.D. Gitlin Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux Proc. Natl. Acad. Sci.U. S. A. 96 1999 10812 10817
18. G. Hoffmann-Fezer, J. Mysliwietz, W. Mortlbauer, H.J. Zeitler, E. Eberle, U. Honle, and S. Thierfelder Biotin labeling as an alternative nonradioactive approach to determination of red cell survival Ann. Hematol. 67 1993 81 87
19. A. Bauer, F. Tronche, O. Wessely, C. Kellendonk, H.M. Reichardt, P. Steinlein, G. Schutz, and H. Beug The glucocorticoid receptor is required for stress erythropoiesis Genes Dev. 13 1999 2996 3002
20. B. Mazumder, C.K. Mukhopadhyay, A. Prok, M.K. Cathcart, and P.L. Fox Induction of ceruloplasmin synthesis by IFN-γ in human monocytic cells J. Immunol. 159 1997 1938 1944
21. A.E. Mast, M.A. Blinder, Q. Lu, S. Flax, and D.J. Dietzen Clinical utility of the reticulocyte hemoglobin content in the diagnosis of iron deficiency Blood 99 2002 1489 1491
22. R.A. Lovstad The protective effect of ceruloplasmin on Fe2+ stimulated lysis of rat erythrocytes Int. J. Biochem. 13 1981 221 224
23. J.M. Caffrey, H.A. Smith, J.C. Schmitz, A. Merchant, and E. Frieden Hemolysis of rabbit erythrocytes in the presence of copper ions: inhibition by albumin and ceruloplasmin Biol. Trace Elem. Res. 25 1990 11 20
24. K.A. Criswell, A.P. Sulkanen, A.F. Hochbaum, and M.R. Bleavins Effects of phenylhydrazine or phlebotomy on peripheral blood, bone marrow and erythropoietin in Wistar rats J. Appl. Toxicol. 20 2000 25 34
25. Z.M. Qian, Y.K. Tsoi, Y. Ke, and M.S. Wong Ceruloplasmin promotes iron uptake rather than release in BT325 cells Exp. Brain Res. 140 2001 369 374
26. C.K. Mukhopadhyay, Z.K. Attieh, and P.L. Fox Role of ceruloplasmin in cellular iron uptake Science 279 1998 714 717
27. Z.K. Attieh, C.K. Mukhopadhyay, V. Seshadri, N.A. Tripoulas, and P.L. Fox Ceruloplasmin ferroxidase activity stimulates cellular iron uptake by a trivalent cation-specific transport mechanism J. Biol. Chem. 274 1999 1116 1123
28. A. Herbik, C. Bolling, and T.J. Buckhout The Involvement of a multicopper oxidase in iron uptake by the green algae Chlamydomonas reinhardtii Plant Physiol. 130 2002 2039 2048
29. S. Osaki, D.A. Johnson, and E. Frieden The possible significance of the ferrous oxidase activity of ceruloplasmin in normal human serum J. Biol. Chem. 241 1966 2746 2751
30. C.D. Vulpe, Y.M. Kuo, T.L. Murphy, L. Cowley, C. Askwith, N. Libina, J. Gitschier, and G.J. Anderson Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse Nat. Genet. 21 1999 195 199
31. H. Chen, Z.K. Attieh, T. Su, B.A. Syed, H. Gao, R.M. Alaeddine, T.C. Fox, J. Usta, C.E. Naylor, R.W. Evans, A.T. McKie, G.J. Anderson, and C.D. Vulpe Hephaestin is a ferroxidase that maintains partial activity in sex-linked anemia mice Blood 103 2004 3933 3939
32. R.M. Bannerman, and R.G. Cooper Sex-linked anemia: a hypochromic anemia of mice Science 151 1966 581 582
33. P.H. Pinkerton, and R.M. Bannerman Hereditary defect in iron absorption in mice Nature 216 1967 482 483
34. J.H. Hutchison The role of copper in iron-deficiency anaemia in infancy Q. J. Med. 7 1938 397 419
35. A. Yamaguchi Studies on ceruloplasmin: especially on its erythropoietic action Showa Med. J. 25 1965 353 366
36. M. Shimizu Clinical results on the use of human ceruloplasmin in aplastic anemia Transfusion (Paris) 19 1979 742 748
37. C.K. Mukhopadhyay, B. Mazumder, and P.L. Fox Role of hypoxia inducible factor-1 in transcriptional activation of ceruloplasmin by iron deficiency J. Biol. Chem. 275 2000 21048 21054
38. V. Seshadri, P.L. Fox, and C.K. Mukhopadhyay Dual role of insulin in transcriptional regulation of the acute phase reactant ceruloplasmin J. Biol. Chem. 277 2002 27903 27911
39. 2-regulated gene expression FASEB J. 16 2002 1151 1162
40. G.L. Semenza HIF-1 and human disease: one highly involved factor Genes Dev. 14 2000 1983 1991
41. M.C. Linder, J.R. Moor, and K. Wright Ceruloplasmin assays in diagnosis and treatment of human lung, breast, and gastrointestinal cancers J. Natl. Cancer Inst. 67 1981 263 275
42. J.Z. Pedersen, and C. Franck Increased serum levels of ceruloplasmin in severe chronic airflow obstruction Eur. J. Respir. Dis. 70 1987 140 144
43. F. Marcos Sanchez, J. Celdran Gil, C. Hernandez Lanchas, and A. Duran Perez-Navarro Increase of ceruloplasmin levels in patients with chronic obstructive pulmonary disease Ann. Med. Interne 9 1992 464
44. M.I. Surks Elevated PBI, free thyroxine, and plasma protein concentration in man at high altitude J. Appl. Physiol. 21 1966 1185 1190