Important role of superoxide dismutase in EDHF-mediated responses of human mesenteric arteries

Journal of Cardiovascular Pharmacology

Volumn 44, Issue 5, 2004, Pages 552-556

  Morikawa, Keiko ^a   Fujiki, Takako ^a   Matoba, Tetsuya ^a   Kubota, Hiroshi ^a   Hatanaka, Makoto ^a   Takahashi, Shosuke ^a   Shimokawa, Hiroaki ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Endothelium derived hyperpolarizing factor; Hydrogen peroxide; Membrane potential; SOD; Vascular endothelium

Indexed keywords

BRADYKININ; COPPER ZINC SUPEROXIDE DISMUTASE; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; HYDROGEN PEROXIDE; INDOMETACIN; N(G) NITROARGININE; NITRIC OXIDE; PROSTACYCLIN; TIRON;

ARTICLE; BLOOD VESSEL REACTIVITY; CELL MEMBRANE STEADY POTENTIAL; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVITY; GASTRECTOMY; HEART MUSCLE POTENTIAL; HUMAN; HUMAN TISSUE; HYPERPOLARIZATION; MESENTERIC ARTERY; MESENTERY BLOOD FLOW; MUSCLE ISOMETRIC CONTRACTION; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

AGED; ANIMALS; BENZIMIDAZOLES; BIOLOGICAL FACTORS; BRADYKININ; CATALASE; DRUG ADMINISTRATION SCHEDULE; DRUG ANTAGONISM; DRUG SYNERGISM; FEMALE; HUMANS; HYDROGEN PEROXIDE; INDOMETHACIN; ISOENZYMES; JAPAN; MALE; MEMBRANE POTENTIALS; MESENTERIC ARTERIES; MUSCLE, SMOOTH, VASCULAR; NITROARGININE; NITROPRUSSIDE; RESEARCH DESIGN; SUPEROXIDE DISMUTASE; SWINE; TIRON; VASODILATION;

EID: 7444235327     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200411000-00006     Document Type: Article

References (32)

1. Shimokawa H. Primary endothelial dysfunction: atherosclerosis. J Mol Cell Cardiol. 1999;31:23-37.
2. Feletou M, Vanhoutte PM. Endothelium-dependent hyperpolarization of canine coronary smooth muscle. Br J Pharmacol. 1988;93:515-524.
3. Chen G, Suzuki H, Weston AH. Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels. Br J Pharmacol. 1988;95:1165-1174.
4. 2 and epoxyeicosatrienoic acids in relaxation of bovine coronary arteries to arachidonic acid. Am J Physiol. 1993;264:H327-H335.
5. Fisslthaler B, Popp R, Kiss L, et al. Cytochrome P450 2C is an EDHF synthase in coronary arteries. Nature. 1999;401:493-497.
6. + is an endothelium-derived hyperpolarizing factor in rat arteries. Nature. 1998;396:269-272.
7. Beny JL, Schaad O. An evaluation of potassium ions as endothelium-derived hyperpolarizing factor in porcine coronary arteries. Br J Pharmacol. 2000;131:965-973.
8. Taylor HJ, Chaytor AT, Evans WH, et al. Inhibition of the gap junctional component of endothelium-dependent relaxations in rabbit iliac artery by 18-alpha glycyrrhetinic acid. Br J Pharmacol. 1998;125:1-3.
9. Yamamoto Y, Imaeda K, Suzuki H. Endothelium-dependent hyperpolarization and intercellular electrical coupling in guinea-pig mesenteric arterioles. J Physiol. 1999;514:505-513.
10. Vanhoutte PM. Endothelium-dependent hyperpolarizations: the history. Pharmacol Res. 2004;49:503-508.
11. Nakashima M, Mombouli JV, Taylor AA, et al. Endothelium-dependent hyperpolarization caused by bradykinin in human coronary arteries. J Clin Invest. 1993;92:2867-2871.
12. Urakami-Harasawa L, Shimokawa H, Nakashima M, et al. Importance of endothelium-derived hyperpolarizing factor in human arteries. J Clin Invest. 1997;100:2793-2799.
13. Inokuchi K, Hirooka Y, Shimokawa H, et al. Role of endothelium-derived hyperpolarizing factor in human forearm circulation. Hypertension. 2003;42:919-924.
14. Matoba T, Shimokawa H, Nakashima M, et al. Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice. J Clin Invest. 2000;106:1521-1530.
15. Matoba T, Shimokawa H, Kubota H, et al. Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in human mesenteric arteries. Biochem Biophys Res Commun. 2002;290:909-913.
16. Matoba T, Shimokawa H, Morikawa K, et al. Electron spin resonance detection of hydrogen peroxide as an endothelium-derived hyperpolarizing factor in porcine coronary microvessels. Arterioscler Thromb Vasc Biol. 2003;23:1224-1230.
17. Lacza Z, Puskar M, Kis B, et al. Hydrogen peroxide acts as an EDHF in the piglet pial vasculature in response to bradykinin. Am J Physiol Heart Circ Physiol. 2002;283:H406-H411.
18. Miura H, Bosnjak JJ, Ning G, et al. Role for hydrogen peroxide in flow-induced dilation of human coronary arterioles. Circ Res. 2003;92:e31-e40.
19. Morikawa K, Shimokawa H, Matoba T, et al. Pivotal role of Cu,Zn-superoxide dismutase in endothelium-dependent hyperpolarization. J Clin Invest. 2003;112:1871-1879.
20. 2 generation play a key role in flow-mediated dilation in human coronary resistance arteries. Circ Res. 2003;93:573-580.
21. Ledenev AN, Konstantinov AA, Popova E, et al. A simple assay of the superoxide generation rate with Tiron as an EPR-visible radical scavenger. Biochem Int. 1986;13:391-396.
22. + channels by novel benzimidazolone. Eur J Pharmacol. 1994;251:53-59.
23. McIntyre M, Bohr DF, Dominiczak AF. Endothelial function in hypertension: the role of superoxide anion. Hypertension. 1999;34:539-545.
24. Fukai T, Siegfried MR, Ushio-Fukai M, et al. Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training. J Clin Invest. 2000;105:1631-1639.
25. Rubanyi GM, Vanhoutte PM. Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor. Am J Physiol. 1986;250:H822-H827.
26. Mugge A, Elwell JH, Peterson TE, et al. Release of intact endothelium-derived relaxing factor depends on endothelial superoxide dismutase activity. Am J Physiol. 1991;260:C219-C225.
27. Fleming I. Cytochrome P450 epoxygenases as EDHF synthase(s). Pharmacol Res. 2004;49:525-533.
28. Griffith TM, Chaytor AT Taylor HJ, et al. cAMP facilitates EDHF-type relaxations in conduit arteries by enhancing electrotonic conduction via gap junctions. Proc Natl Acad Sci USA. 2002;99:6392-6397.
29. Griffith TM, Chaytor AT, Edwards DH. The obligatory link: role of gap junctional communication in endothelium-dependent smooth muscle hyperpolarization. Pharmacol Res. 2004;49:551-564.
30. Uchimura K, Nagasaka A, Hayashi R, et al. Changes in superoxide dismutase activities and concentrations and myeloperoxidase activities in leukocytes from patients with diabetes mellitus. J Diabetes Complications. 1999;13:264-270.
31. Wu R, Millette E, Wu L, et al. Enhanced superoxide anion formation in vascular tissues from spontaneously hypertensive and desoxycorticosterone acetate-salt hypertensive rats. J Hypertens. 2001;19:741-748.
32. Noor R, Mittal S, Iqbal J. Superoxide dismutase-applications and relevance to human diseases. Med Sci Monit. 2002;8:RA210-RA215.