Fourier transform ion cyclotron resonance MS reveals the presence of a water molecule in an enzyme transition-state analogue complex

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 43, 2004, Pages 15341-15345

  Borchers, Christoph H ^a   Marquez, Victor E ^b   Schroeder, Gottfried K ^a   Short, Steven A ^c   Snider, Mark J ^d   Speir, J Paul ^e   Wolfenden, Richard ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c GLAXOSMITHKLINE   (United States)

^d 931 College Mall   (United States)

^e BRUKER DALTONIK GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE DEAMINASE; URIDINE DERIVATIVE; WATER; ZINC;

ARTICLE; DIMERIZATION; ELECTROSPRAY; ENZYME ACTIVE SITE; ENZYME REPLACEMENT; ESCHERICHIA COLI; ION CYCLOTRON RESONANCE MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN; PH MEASUREMENT; PHASE TRANSITION; PRIORITY JOURNAL; VAPOR;

CYCLOTRONS; CYTIDINE DEAMINASE; ESCHERICHIA COLI; FOURIER ANALYSIS; HYDROGEN-ION CONCENTRATION; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; WATER;

ESCHERICHIA COLI; POSIBACTERIA;

EID: 7444221098     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0406781101     Document Type: Article

References (12)

1. Wolfenden, R. (1972) Acc. Chem. Res. 5, 10-18.
2. Lienhard, G. E. (1973) Science 180, 149-155.
3. Wolfenden, R. & Kati, W. M. (1991) Acc. Chem. Res. 23, 209-215.
4. Betts, L., Xiang, S., Short, S. A., Wolfenden, R. & Carter, C. W., Jr. (1994) J. Mol. Biol. 235, 635-656.
5. Carlow, D., Short S. A. & Wolfenden, R. (1996) Biochemistry 35, 948-954.
6. Snider, M. J., Reinhardt, L., Wolfenden, R. & Cleland, W. W. (2002) Biochemistry 41, 415-421.
7. Snider, M. J. & Wolfenden, R. (2001) Biochemistry 40, 11364-11371.
8. Xiang, S., Short, S. A., Wolfenden, R. & Carter, C. W., Jr. (1997) Biochemistry 36, 4768-4774.
9. Felitsyn, N., Peschke, R. & Kebarle, P. (2002) Int. J. Mass Spectrom. 219, 39-62.
10. Yang, C., Carlow, D., Wolfenden, R. & Short, S. A. (1992) Biochemistry 31, 4168-4173.
11. Smith, A. A., Carlow, D., Wolfenden, R. & Short, S. A. (1994) Biochemistry 33, 6468-6474.
12. Cohen, R. & Wolfenden, R. (1971) J. Biol. Chem. 246, 7561-7565.