Inducible expression of V600EBraf using tyrosinase-driven Cre recombinase results in embryonic lethality

Pigment Cell and Melanoma Research

Volumn 23, Issue 1, 2010, Pages 112-120

  Dhomen, Nathalie ^a   Da Rocha Dias, Silvy ^a   Hayward, Robert ^a   Ogilvie, Lesley ^b   Hedley, Douglas ^b   Delmas, Veronique ^c,d   McCarthy, Afshan ^b   Henderson, Deborah ^e   Springer, Caroline J ^b   Pritchard, Catrin ^f   Larue, Lionel ^c,d   Marais, Richard ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c INSTITUT CURIE   (France)

^d CNRS UMR146   (France)

^e NEWCASTLE UNIVERSITY   (United Kingdom)

^f UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

V600EBraf; Cre recombinase; Inducible expression; Melanoblasts; Tyrosi nase promoter

Indexed keywords

B RAF KINASE; CRE RECOMBINASE; MONOPHENOL MONOOXYGENASE;

ARTICLE; BIRTH; BRAIN MALFORMATION; CELL PROLIFERATION; CELL TRANSFORMATION; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; EMBRYO; EYE MALFORMATION; LETHALITY; MELANOCYTE; MELANOMA; MORTALITY; MOUSE; NONHUMAN; ORGAN; SKIN DEFECT; STEM CELL; TERMINAL DISEASE;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CONGENITAL ABNORMALITIES; EMBRYONIC DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCK-IN TECHNIQUES; GENES, LETHAL; INTEGRASES; MELANOCYTES; MELANOMA; MICE; MICE, TRANSGENIC; MONOPHENOL MONOOXYGENASE; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS B-RAF; SKIN NEOPLASMS; STEM CELLS;

ANIMALIA; MUS;

EID: 74349119662     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2009.00662.x     Document Type: Article

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