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74349116096
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also called toxicophores: molecular substructures which are known for having or modulating a toxicological effect. An example is given in figure 2
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Structural alert, also called toxicophores: molecular substructures which are known for having or modulating a toxicological effect. An example is given in figure 2.
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Structural Alert
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2
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74349092023
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Read-across: methodology based on the principle of toxicological analogy among chemicals whose physico-chemical, toxicological and ecotoxicological properties are likely to be similar or follow a regular pattern as a result of structural similarity
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Read-across: methodology based on the principle of toxicological analogy among chemicals whose physico-chemical, toxicological and ecotoxicological properties are likely to be similar or follow a regular pattern as a result of structural similarity.
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3
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84868054815
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A guidance document has recently been issued
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A guidance document has recently been issued: www.oecd.org/document/23/0, 3343,en-2649-34377-33957015-1-1-1-37465,00.html
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4
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74349130736
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Computational models that describe the processes of uptake, distribution, metabolism and excretion of a xenobiotic in order to study its effects in the body over time
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Computational models that describe the processes of uptake, distribution, metabolism and excretion of a xenobiotic in order to study its effects in the body over time.
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6
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0348167081
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Van Der Jagt, K.1
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Danish Environmental Protection Agency, Danish (Q)SAR Database
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Danish Environmental Protection Agency, Danish (Q)SAR Database, http://130.226.165.14/index.html
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US FDA, CDER, ICSAS
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Evaluation of (Q)SAR models for the prediction of mutagenicity potential
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