Antifertility characteristics of the N-terminal region of mouse equatorial segment protein

Anatomical Record

Volumn 293, Issue 1, 2010, Pages 171-181

  Lv, Zheng Mei ^a,b,c   Wang, Min ^a,b   Xu, Chen ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Shanghai Key Laboratory for Reproductive Medicine   (China)

^c ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Equatorial segment protein; Gene expression; Immunocontraception; Sperm ovum interactions

Indexed keywords

COMPLEMENTARY DNA; EQUATORIAL SEGMENT PROTEIN; RECOMBINANT PROTEIN; SPERM ANTIGEN; UNCLASSIFIED DRUG;

ACROSOME; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; CONTRACEPTION; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; FEMALE FERTILITY; FERTILIZATION IN VITRO; IMMUNOLOCALIZATION; MALE; MASS SPECTROMETRY; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ANIMALS; BLOTTING, WESTERN; CELL MEMBRANE; CONTRACEPTION, IMMUNOLOGIC; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FERTILIZATION IN VITRO; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; IMMUNIZATION; INFERTILITY; MALE; MICE; MICE, INBRED BALB C; OOCYTES; RABBITS; SEMINAL PLASMA PROTEINS; SPERM CAPACITATION; SPERM-OVUM INTERACTIONS; VACCINES, CONTRACEPTIVE;

MUS;

EID: 74249119692     PISSN: 19328486     EISSN: 19328494     Source Type: Journal    
DOI: 10.1002/ar.21032     Document Type: Article

References (26)

1. Auer J, Senechal H, Desvaux F, Albert M, De Almeida M. 2000. Isolation and characterization of two sperm membrane proteins recognized by sperm-associated antibodies in infertile men. Mol Reprod Dev 57:393-405.
2. Bhande S, Naz RK. 2007. Molecular identities of human sperm proteins reactive with antibodies in sera of immunoinfertile women. Mol Reprod Dev 74:332-340.
3. Cho C, Bunch DO, Faure JE, Goulding EH, Eddy EM, Primakoff P, Myles DG. 1998. Fertilization defects in sperm from mice lacking fertilin β. Science 281:1857-1859.
4. Cohen DJ, Ellerman DA, Busso D, Morgenfeld MM, Piazza AD, Hayashi M, Young ET, Kasahara M, Cuasnicu PS. 2001. Evidence that human epididymal protein ARP plays a role in gamete fusion through complementary sites on the surface of the human egg. Biol Reprod 65:1000-1005.
5. Ellerman DA, Cohen DJ, Da Ros VG, Morgenfeld MM, Busso D, Cuasnicú PS. 2006. Sperm protein ́DÉ mediates gamete fusion through an evolutionarily conserved site of the CRISP family. Dev Biol 297:228-237.
6. Evans JP. 2002. The molecular basis of sperm-oocyte membrane interactions during mammalian fertilization. Hum Reprod Update 8:297-311.
7. Frayne J, Hall L. 1999. The potential use of sperm antigens as targets for immunocontraception; past, present and future. J Reprod Immunol 43:1-33.
8. Fuentes P, Palacio JR, Mayorga M, Martínez P. 2006. Inhibition of in vitro gamete adhesion and in vivo fertility in mice by immunization with a synthetic peptide. Clin Immunol 119:195-202.
9. Gaudreault C, Montfort L, Sullivan R. 2002. Effect of immunization of hamsters against recombinant P26h on fertility rates. Reproduction 123:307-313.
10. Hardy CM, Beaton S, Hinds LA. 2008. Immunocontraception in mice using repeated, multi-antigen peptides: immunization with purified recombinant antigens. Mol Reprod Dev 75:126-135.
11. Hardy CM, Clydesdale G, Mobbs KJ. 2004a. Development of mouse-specific contraceptive vaccines: infertility in mice immunized with peptide and polyepitope antigens. Reproduction 128:395-407.
12. Hardy CM, Clydesdale G, Mobbs KJ, Pekin J, Lloyd ML, Sweet C, Shellam GR, Lawson MA. 2004b. Assessment of contraceptive vaccines based on recombinant mouse sperm protein PH20. Reproduction 127:325-334.
13. Herrero MB, Mandal A, Digilio LC, Coonrod SA, Maier B, Herr JC. 2005. Mouse SLLP1, a sperm lysozyme-like protein involved in sperm-egg binding and fertilization. Dev Biol 284:126-142.
14. Inoue N, Ikawa M, Isotani A, Okabe M. 2005. The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs. Nature 434:234-238.
15. Kurth BE, Digilio L, Snow P, Bush LA, Wolkowicz M, Shetty J, Mandal A, Hao Z, Reddi PP, Flickinger CJ, Herr JC. 2008. Immunogenicity of a multi-component recombinant human acrosomal protein vaccine in female Macaca fascicularis. J Reprod Immunol 77:126-141.
16. Lea IA, Kurth B, O'Rand MG. 1998. Immune response to immunization with sperm antigens in the macaque oviduct. Biol Reprod 58:794-800.
17. Naz RK. 1999. Vaccine for contraception targeting sperm. Immunol Rev 171:193-202.
18. Naz RK. 2008. Immunocontraceptive effect of Izumo and enhancement by combination vaccination. Mol Reprod Dev 75:336-344.
19. Naz RK, Gupta SK, Gupta JC, Vyas HK, Talwar AG. 2005. Recent advances in contraceptive vaccine development: a mini-review. Hum Reprod 20:3271-3283.
20. Naz RK, Zhu X. 1998. Recombinant fertilization antigen-1 causes a contraceptive effect in actively immunized mice. Biol Reprod 59:1095-1100.
21. Ohta T. 1991. Initial stages of sperm-egg fusion in the freshwater teleost, Rhodeus ocellatus ocellatus. Anat Rec 229:195-202.
22. Primakoff P, Woolman-Gamer L, Tung KS, Myles DG. 1997. Reversible contraceptive effect of PH-20 immunization in male guinea pigs. Biol Reprod 56:1142-1146.
23. Shi JL, Yang ZM, Wang M, Cheng GY, Li D, Wang Y, Zhou Y, Liu X, Xu C. 2007. Screening of an antigen target for immunocontraceptives from cross-reactive antigens between human sperm and ureaplasma urealyticum. Infect Immun 75:2004-2011.
24. Wolkowicz MJ, Digilio L, Klotz K, Shetty J, Flickinger CJ, Herr JC. 2008. Equatorial segment protein (ESP) is a human alloantigen involved in sperm-egg binding and fusion. J Androl 29:272-282.
25. Wolkowicz MJ, Shetty J, Westbrook A, Klotz K, Jayes F, Mandal A, Flickinger CJ, Herr JC. 2003. Equatorial segment protein defines a discrete acrosomal subcompartment sersisting throughout acrosomal biogenesis. Biol Reprod 69:735-745.
26. Zhou D, Srivastava R, Nessler S, Grummel V, Sommer N, Brück W, Hartung HP, Stadelmann C, Hemmer B. 2006. Identification of a pathogenic antibody response to native myelin oligodendrocyte glycoprotein in multiple sclerosis. Proc Natl Acad Sci USA 103:19057-19062.