TSC-22D1 isoforms have opposing roles in mammary epithelial cell survival

Cell Death and Differentiation

Volumn 17, Issue 2, 2010, Pages 304-315

  Huser, C A ^a   Pringle, M A ^a   Heath, V J ^a,b   Bell, A K ^a   Kendrick, H ^c   Smalley, M J ^c   Crighton, D ^d   Ryan, K M ^d   Gusterson, B A ^a   Stein, T ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b Nature Publishing Group Palgrave Macmillan   (United Kingdom)

^c INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^d BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

Apoptosis; Involution; Mammary gland; Proliferation; TSC 22 isoforms

Indexed keywords

ISOPROTEIN; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA STIMULATED CLONE 22 DOMAIN FAMILY MEMBER 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST EPITHELIUM; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DEVELOPMENT; EPITHELIUM CELL; GENE EXPRESSION; INVOLUTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION; WEANING;

ANIMALS; APOPTOSIS; CELL DIVISION; CELL SURVIVAL; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION; ISOMERISM; MAMMARY GLANDS, ANIMAL; MICE; MICE, INBRED STRAINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REPRESSOR PROTEINS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA3;

MAMMALIA;

EID: 74249118618     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2009.126     Document Type: Article

References (39)

1. Richert MM, Schwertfeger KL, Ryder JW, Anderson SM. An atlas of mouse mammary gland development. J Mammary Gland Biol Neoplasia 2000; 5: 227-241.
2. Lund LR, Romer J, Thomasset N, Solberg H, Pyke C, Bissell MJ et al. Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and-dependent pathways. Development 1996; 122: 181-193.
3. Stein T, Salomonis N, Gusterson BA. Mammary gland involution as a multi-step process. J Mammary Gland Biol Neoplasia 2007; 12: 25-35.
4. Li M, Hu J, Heermeier K, Hennighausen L, Furth PA. Apoptosis and remodeling of mammary gland tissue during involution proceeds through p53-independent pathways. Cell Growth Differ 1996; 7: 13-20.
5. Li M, Liu X, Robinson G, Bar-Peled U, Wagner KU, Young WS et al. Mammary-derived signals activate programmed cell death during the first stage of mammary gland involution. Proc Natl Acad Sci USA 1997; 94: 3425-3430.
6. Monks J, Geske FJ, Lehman L, Fadok VA. Do inflammatory cells participate in mammary gland involution? J Mammary Gland Biol Neoplasia 2002; 7: 163-176.
7. Stein T, Morris JS, Davies CR, Weber-Hall SJ, Duffy MA, Heath VJ et al. Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3. Breast Cancer Res 2004; 6: R75-R91.
8. Humphreys RC, Bierie B, Zhao L, Raz R, Levy D, Hennighausen L. Deletion of Stat3 blocks mammary gland involution and extends functional competence of the secretory epithelium in the absence of lactogenic stimuli. Endocrinology 2002; 143: 3641-3650.
9. Thangaraju M, Rudelius M, Bierie B, Raffeld M, Sharan S, Hennighausen L et al. C/EBPdelta is a crucial regulator of pro-apoptotic gene expression during mammary gland involution. Development 2005; 132: 4675-4685.
10. Merto GR, Cella N, Hynes NE. Apoptosis is accompanied by changes in Bcl-2 and Bax expression, induced by loss of attachment, and inhibited by specific extracellular matrix proteins in mammary epithelial cells. Cell Growth Differ 1997; 8: 251-260.
11. Nguyen AV, Pollard JW. Transforming growth factor beta3 induces cell death during the first stage of mammary gland involution. Development 2000; 127: 3107-3118.
12. Shibanuma M, Kuroki T, Nose K. Isolation of a gene encoding a putative leucine zipper structure that is induced by transforming growth factor beta 1 and other growth factors. J Biol Chem 1992; 267: 10219-10224.
13. Ghedin E, Wang S, Spiro D, Caler E, Zhao Q, Crabtree J et al. Draft genome of the filarial nematode parasite Brugia malayi. Science 2007; 317: 1756-1760.
14. Dobens LL, Peterson JS, Treisman J, Raftery LA. Drosophila bunched integrates opposing DPP and EGF signals to set the operculum boundary. Development 2000; 127: 745-754.
15. Dohrmann CE, Noramly S, Raftery LA, Morgan BA. Opposing effects on TSC-22 expression by BMP and receptor tyrosine kinase signals in the developing feather tract. Dev Dyn 2002; 223: 85-95.
16. Fiol DF, Kultz D. Rapid hyperosmotic coinduction of two tilapia (Oreochromis mossambicus) transcription factors in gill cells. Proc Natl Acad Sci USA 2005; 102: 927-932.
17. Hashiguchi A, Okabayashi K, Asashima M. Role of TSC-22 during early embryogenesis in Xenopus laevis. Dev Growth Differ 2004; 46: 535-544.
18. Uchida D, Kawamata H, Omotehara F, Miwa Y, Hino S, Begum NM et al. Over-expression of TSC-22 (TGF-beta stimulated clone-22) markedly enhances 5-fluorouracil-induced apoptosis in a human salivary gland cancer cell line. Lab Invest 2000; 80: 955-963.
19. Dohrmann CE, Belaoussoff M, Raftery LA. Dynamic expression of TSC-22 at sites of epithelial-mesenchymal interactions during mouse development. Mech Dev 1999; 84: 147-151.
20. Choi SJ, Moon JH, Ahn YW, Ahn JH, Kim DU, Han TH. Tsc-22 enhances TGF-beta signaling by associating with Smad4 and induces erythroid cell differentiation. Mol Cell Biochem 2005; 271: 23-28.
21. Kawamata H, Nakashiro K, Uchida D, Hino S, Omotehara F, Yoshida H et al. Induction of TSC-22 by treatment with a new anti-cancer drug, vesnarinone, in a human salivary gland cancer cell. Br J Cancer 1998; 77: 71-78.
22. Gupta RA, Sarraf P, Mueller E, Brockman JA, Prusakiewicz JJ, Eng C et al. Peroxisome proliferator-activated receptor gamma-mediated differentiation: a mutation in colon cancer cells reveals divergent and cell type-specific mechanisms. J Biol Chem 2003; 278: 22669-22677.
23. Hino S, Kawamata H, Uchida D, Omotehara F, Miwa Y, Begum NM et al. Nuclear translocation of TSC-22 (TGF-beta-stimulated clone-22) concomitant with apoptosis: TSC-22 as a putative transcriptional regulator. Biochem Biophys Res Commun 2000; 278: 659-664.
24. Dobens LL, Hsu T, Twombly V, Gelbart WM, Raftery LA, Kafatos FC. The Drosophila bunched gene is a homologue of the growth factor stimulated mammalian TSC-22 sequence and is required during oogenesis. Mech Dev 1997; 65: 197-208.
25. Treisman JE, Lai ZC, Rubin GM. Shortsighted acts in the decapentaplegic pathway in Drosophila eye development and has homology to a mouse TGF-beta-responsive gene. Development 1995; 121: 2835-2845.
26. Jay P, Ji JW, Marsollier C, Taviaux S, Berge-Lefranc JL, Berta P. Cloning of the human homologue of the TGF beta-stimulated clone 22 gene. Biochem Biophys Res Commun 1996; 222: 821-826.
27. Kester HA, Ward-van Oostwaard TM, Goumans MJ, van Rooijen MA, van Der Saag PT, van Der Burg B et al. Expression of TGF-beta stimulated clone-22 (TSC-22) in mouse development and TGF-beta signalling. Dev Dyn 2000; 218: 563-572.
28. Ohta S, Shimekake Y, Nagata K. Molecular cloning and characterization of a transcription factor for the C-type natriuretic peptide gene promoter. Eur J Biochem 1996; 242: 460-466.
29. Kester HA, Blanchetot C, den Hertog J, van der Saag PT, van der Burg B. Transforming growth factor-beta-stimulated clone-22 is a member of a family of leucine zipper proteins that can homo-and heterodimerize and has transcriptional repressor activity. J Biol Chem 1999; 274: 27439-27447.
30. Gordon KE, Binas B, Chapman RS, Kurian KM, Clarkson RW, Clark AJ et al. A novel cell culture model for studying differentiation and apoptosis in the mouse mammary gland. Breast Cancer Res 2000; 2: 222-235.
31. Sleeman KE, Kendrick H, Ashworth A, Isacke CM, Smalley MJ. CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells. Breast Cancer Res 2006; 8: R7.
32. Sleeman KE, Kendrick H, Robertson D, Isacke CM, Ashworth A, Smalley MJ. Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland. J Cell Biol 2007; 176: 19-26.
33. Nakashiro K, Kawamata H, Hino S, Uchida D, Miwa Y, Hamano H et al. Down-regulation of TSC-22 (transforming growth factor beta-stimulated clone 22) markedly enhances the growth of a human salivary gland cancer cell line in vitro and in vivo. Cancer Res 1998; 58: 549-555.
34. Yu J, Ershler M, Yu L, Wei M, Hackanson B, Yokohama A et al. TSC-22 contributes to hematopoietic precursor cell proliferation and repopulation and is epigenetically silenced in large granular lymphocyte leukemia. Blood 2009; 113: 5558-5567.
35. Gluderer S, Oldham S, Rintelen F, Sulzer A, Schutt C, Wu X et al. Bunched, the Drosophila homolog of the mammalian tumor suppressor TSC-22, promotes cellular growth. BMC Dev Biol 2008; 8: 10.
36. Wu X, Yamada-Mabuchi M, Morris EJ, Tanwar PS, Dobens L, Gluderer S et al. The Drosophila homolog of human tumor suppressor TSC-22 promotes cellular growth, proliferation, and survival. Proc Natl Acad Sci USA 2008; 105: 5414-5419. (Pubitemid 351753877)
37. Daniel CW, Robinson S, Silberstein GB. The transforming growth factors beta in development and functional differentiation of the mouse mammary gland. Adv Exp Med Biol 2001; 501: 61-70.
38. Robinson SD, Silberstein GB, Roberts AB, Flanders KC, Daniel CW. Regulated expression and growth inhibitory effects of transforming growth factor-beta isoforms in mouse mammary gland development. Development 1991; 113: 867-878.
39. Ryan KM, Ernst MK, Rice NR, Vousden KH. Role of NF-kappaB in p53-mediated programmed cell death. Nature 2000; 404: 892-897.