P-Selectin and P-Selectin glycoprotein ligand 1 mediate rolling of activated cd8+ t cells in inflamed colonic venules

Journal of Investigative Medicine

Volumn 57, Issue 7, 2009, Pages 765-768

  Asaduzzaman, Muhammad ^a   Mihaescu, Andrada ^a   Wang, Yusheng ^a   Sato, Tohru ^b   Thorlacius, Henrik ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adhesion; Colon; Inflammation; Lymphocyte; Rolling

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; P SELECTIN GLYCOPROTEIN LIGAND 1; PADGEM PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CELL ADHESION; CELL INTERACTION; COLITIS; CONTROLLED STUDY; ENDOTHELIUM; FLUORESCENCE MICROSCOPY; GRAFT VERSUS HOST REACTION; LARGE INTESTINE; MALE; MOUSE; NONHUMAN; SPLEEN CELL; T LYMPHOCYTE ACTIVATION; VENULE;

MUS;

EID: 74249115104     PISSN: 17088267     EISSN: None     Source Type: Journal    
DOI: 10.2310/JIM.0b013e3181b918fb     Document Type: Article

References (9)

1. Butcher EC, Picker LJ. Lymphocyte homing and homeostasis. Science. 1996;272:60-66.
2. Vestweber D, Blanks JE. Mechanisms that regulate the function of the selectins and their ligands. Physiol Rev. 1999;79:181-213.
3. Hirata T, Merrill-Skoloff G, Aab M, et al. P-selectin glycoprotein ligand 1 (PSGL-1) is a physiological ligand for E-selectin in mediating T helper 1 lymphocyte migration. J Exp Med. 2005;192:1669-1676.
4. + lymphocytes to inflamed liver. J Immunol. 2005;174:277-283.
5. Knibbs RN, Craig RA, Mály P. Alpha(1,3)-fucosyltransferase VIIYdependent synthesis of P- and E-selectin ligands on cultured T lymphoblasts. J Immunol. 1998;161:6305-6315.
6. Riaz AA, Wan MX, Schaefer T. Fundamental and distinct roles of P-selectin and LFA-1 in ischemia/reperfusionYinduced leukocyte-endothelium interactions in the mouse colon. Ann Surg. 2002;236:777-874.
7. Kunkel EJ, Jung U, Bullard DC, et al. Absence of trauma-induced leukocyte rolling in mice deficient in both P-selectin and intercellular adhesion molecule 1. J Exp Med. 1996;183:57-65.
8. H2 lymphocyte rolling in the intestinal microvasculature. Am J Pathol. 2005;167:1647-1660.
9. Rivera-Nieves J, Burcin TL, Olson TS. Critical role of endothelial P-selectin glycoprotein ligand 1 in chronic murine ileitis. J Exp Med. 2006;203:907-917.