-
1
-
-
50549123220
-
On the treatment of inoperable cases of carcinoma of the mammary: Suggestions for a new method of treatment, with illustrative cases
-
Beatson G: On the treatment of inoperable cases of carcinoma of the mammary: Suggestions for a new method of treatment, with illustrative cases. Lancet 2:104-107, 1896.
-
(1896)
Lancet
, vol.2
, pp. 104-107
-
-
Beatson, G.1
-
2
-
-
0032569831
-
Tamoxifen in the treatment of breast cancer
-
Osborne CK: Tamoxifen in the treatment of breast cancer. N Engl J Med 339:1609-1618, 1998.
-
(1998)
N Engl J Med
, vol.339
, pp. 1609-1618
-
-
Osborne, C.K.1
-
3
-
-
19344364880
-
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
-
Early Breast Cancer Trialists Collaborative Group
-
Early Breast Cancer Trialists Collaborative Group: Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials. Lancet 365:1687-1717, 2005.
-
(2005)
Lancet
, vol.365
, pp. 1687-1717
-
-
-
4
-
-
0032537990
-
Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study
-
Fisher B, Costantino JP, Wickerham DL, et al: Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst 90:1371-1388, 1998.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1371-1388
-
-
Fisher, B.1
Costantino, J.P.2
Wickerham, D.L.3
-
5
-
-
0033549344
-
Tamoxifen in treatment of intraductal breast cancer: National Surgical Adjuvant Breast and Bowel Project B-24 randomised controlled trial
-
Fisher B, Dignam J, Wolmark N, et al: Tamoxifen in treatment of intraductal breast cancer: National Surgical Adjuvant Breast and Bowel Project B-24 randomised controlled trial. Lancet 353:1993-2000, 1999.
-
(1999)
Lancet
, vol.353
, pp. 1993-2000
-
-
Fisher, B.1
Dignam, J.2
Wolmark, N.3
-
6
-
-
0026500848
-
Adjuvant tamoxifen for male breast cancer (MBC)
-
Ribeiro G, Swindell R: Adjuvant tamoxifen for male breast cancer (MBC). Br J Cancer 65:252-254, 1992.
-
(1992)
Br J Cancer
, vol.65
, pp. 252-254
-
-
Ribeiro, G.1
Swindell, R.2
-
7
-
-
19944422061
-
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
-
Paik S, Shak S, Tang G, et al: A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med 351:2817-2826, 2004.
-
(2004)
N Engl J Med
, vol.351
, pp. 2817-2826
-
-
Paik, S.1
Shak, S.2
Tang, G.3
-
8
-
-
67649364451
-
Aromatase inhibitors versus tamoxifen as adjuvant therapy for postmenopausal women with estrogen receptor positive breast cancer: Meta-analyses of randomized trials of monotherapy and switching strategies (abstract 12)
-
66s
-
Ingle JN, Dowsett M, Cuzick J, et al: Aromatase inhibitors versus tamoxifen as adjuvant therapy for postmenopausal women with estrogen receptor positive breast cancer: Meta-analyses of randomized trials of monotherapy and switching strategies (abstract 12). Cancer Res 69(suppl 2):66s, 2009.
-
(2009)
Cancer Res
, vol.69
, Issue.SUPPL. 2
-
-
Ingle, J.N.1
Dowsett, M.2
Cuzick, J.3
-
9
-
-
11444251764
-
Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years adjuvant treatment for breast cancer
-
Howell A, Cuzick J, Baum M, et al: Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years adjuvant treatment for breast cancer. Lancet 365:60-62, 2005.
-
(2005)
Lancet
, vol.365
, pp. 60-62
-
-
Howell, A.1
Cuzick, J.2
Baum, M.3
-
10
-
-
37449028688
-
Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial
-
Forbes JF, Cuzick J, Buzdar A, et al: Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial. Lancet Oncol 9:45-53, 2008.
-
(2008)
Lancet Oncol
, vol.9
, pp. 45-53
-
-
Forbes, J.F.1
Cuzick, J.2
Buzdar, A.3
-
11
-
-
29544433211
-
A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer
-
Thurlimann B, Keshaviah A, Coates AS, et al: A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer. N Engl J Med 353:2747-2757, 2005.
-
(2005)
N Engl J Med
, vol.353
, pp. 2747-2757
-
-
Thurlimann, B.1
Keshaviah, A.2
Coates, A.S.3
-
12
-
-
0017665570
-
A monohydroxylated metabolite of tamoxifen with potent antioestrogenic activity
-
Jordan VC, Collins MM, Rowsby L, et al: A monohydroxylated metabolite of tamoxifen with potent antioestrogenic activity. J Endocrinol 75:305-316, 1977.
-
(1977)
J Endocrinol
, vol.75
, pp. 305-316
-
-
Jordan, V.C.1
Collins, M.M.2
Rowsby, L.3
-
13
-
-
0017695082
-
Polymorphic hydroxylation of Debrisoquine in man
-
Mahgoub A, Idle JR, Dring LG, et al: Polymorphic hydroxylation of Debrisoquine in man. Lancet 2:584-586, 1977.
-
(1977)
Lancet
, vol.2
, pp. 584-586
-
-
Mahgoub, A.1
Idle, J.R.2
Dring, L.G.3
-
14
-
-
34548650021
-
CYP2D6 polymorphisms and the impact on tamoxifen therapy
-
Beverage JN, Sissung TM, Sion AM, et al: CYP2D6 polymorphisms and the impact on tamoxifen therapy. J Pharm Sci 96:2224-2231, 2007.
-
(2007)
J Pharm Sci
, vol.96
, pp. 2224-2231
-
-
Beverage, J.N.1
Sissung, T.M.2
Sion, A.M.3
-
15
-
-
0031949132
-
-
Dalen P, Dahl ML, Bernal Ruiz ML, et al: 10-Hydroxylation of nortriptyline in white persons with 0, 1, 2, 3, and 13 functional CYP2D6 genes. Clin Pharmacol Ther 63:444-452, 1998.
-
Dalen P, Dahl ML, Bernal Ruiz ML, et al: 10-Hydroxylation of nortriptyline in white persons with 0, 1, 2, 3, and 13 functional CYP2D6 genes. Clin Pharmacol Ther 63:444-452, 1998.
-
-
-
-
16
-
-
0036124107
-
CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
-
Bradford LD: CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics 3:229-243, 2002.
-
(2002)
Pharmacogenomics
, vol.3
, pp. 229-243
-
-
Bradford, L.D.1
-
17
-
-
33644639136
-
Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes
-
Goetz MP, Rae JM, Suman VJ, et al: Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes. J Clin Oncol 23:9312-9318, 2005.
-
(2005)
J Clin Oncol
, vol.23
, pp. 9312-9318
-
-
Goetz, M.P.1
Rae, J.M.2
Suman, V.J.3
-
18
-
-
0037087582
-
Phase III evaluation of fluoxetine for treatment of hot flashes
-
Loprinzi CL, Sloan JA, Perez EA, et al: Phase III evaluation of fluoxetine for treatment of hot flashes. J Clin Oncol 20:1578-1583, 2002.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1578-1583
-
-
Loprinzi, C.L.1
Sloan, J.A.2
Perez, E.A.3
-
19
-
-
0037976797
-
Paroxetine controlled release in the treatment of menopausal hot flashes: A randomized controlled trial
-
Stearns V, Beebe KL, Iyengar M, et al: Paroxetine controlled release in the treatment of menopausal hot flashes: A randomized controlled trial. JAMA 289:2827-2834, 2003.
-
(2003)
JAMA
, vol.289
, pp. 2827-2834
-
-
Stearns, V.1
Beebe, K.L.2
Iyengar, M.3
-
20
-
-
34250687523
-
Clinical update: New treatments for hot flushes
-
Stearns V: Clinical update: New treatments for hot flushes. Lancet 369:2062-2064, 2007.
-
(2007)
Lancet
, vol.369
, pp. 2062-2064
-
-
Stearns, V.1
-
21
-
-
74249122766
-
Patterns of Care in Medical
-
Love N: Patterns of Care in Medical Oncology 2(3), 2005.
-
(2005)
Oncology
, vol.2
, Issue.3
-
-
Love, N.1
-
22
-
-
0346602691
-
Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine
-
Stearns V, Johnson MD, Rae JM, et al: Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine. J Natl Cancer Inst 95:1758-1764, 2003.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 1758-1764
-
-
Stearns, V.1
Johnson, M.D.2
Rae, J.M.3
-
23
-
-
19944434201
-
CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment
-
Jin Y, Desta Z, Stearns V, et al: CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment. J Natl Cancer Inst 97:30-39, 2005.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 30-39
-
-
Jin, Y.1
Desta, Z.2
Stearns, V.3
-
24
-
-
0025251643
-
Tamoxifen metabolites in patients on long-term adjuvant therapy for breast cancer
-
Langan-Fahey SM, Tormey DC, Jordan VC: Tamoxifen metabolites in patients on long-term adjuvant therapy for breast cancer. Eur J Cancer 26:883-888, 1990.
-
(1990)
Eur J Cancer
, vol.26
, pp. 883-888
-
-
Langan-Fahey, S.M.1
Tormey, D.C.2
Jordan, V.C.3
-
25
-
-
67651177578
-
Genotype-guided tamoxifen therapy: Time to pause for reflection?
-
Lash TL, Lien EA, Sorensen HT, et al: Genotype-guided tamoxifen therapy: Time to pause for reflection? Lancet Oncol 10:825-833, 2009.
-
(2009)
Lancet Oncol
, vol.10
, pp. 825-833
-
-
Lash, T.L.1
Lien, E.A.2
Sorensen, H.T.3
-
26
-
-
33745926220
-
Randomized trial of tamoxifen alone or combined with fluoxymesterone as adjuvant therapy in postmenopausal women with resected estrogen receptor positive breast cancer. North Central Cancer Treatment Group Trial 89-30-52
-
Ingle JN, Suman VJ, Mailliard JA, et al: Randomized trial of tamoxifen alone or combined with fluoxymesterone as adjuvant therapy in postmenopausal women with resected estrogen receptor positive breast cancer. North Central Cancer Treatment Group Trial 89-30-52. Breast Cancer Res Treat 98:217-222, 2006.
-
(2006)
Breast Cancer Res Treat
, vol.98
, pp. 217-222
-
-
Ingle, J.N.1
Suman, V.J.2
Mailliard, J.A.3
-
27
-
-
33847034287
-
The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen
-
Goetz MP, Knox SK, Suman VJ, et al: The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen. Breast Cancer Res Treat 101:113-121, 2007.
-
(2007)
Breast Cancer Res Treat
, vol.101
, pp. 113-121
-
-
Goetz, M.P.1
Knox, S.K.2
Suman, V.J.3
-
28
-
-
74249086681
-
Tamoxifen pharmacogenetics of CYP2D6, CYP2C19, and SULT1A1: Long term follow-up of the North Central Cancer Treatment Group 89-30-52 adjuvant trial (abstract 6037)
-
Goetz MP, Suman V, Ames M, et al: Tamoxifen pharmacogenetics of CYP2D6, CYP2C19, and SULT1A1: Long term follow-up of the North Central Cancer Treatment Group 89-30-52 adjuvant trial (abstract 6037). Cancer Res 69(suppl), 2009.
-
(2009)
Cancer Res
, vol.69
, Issue.SUPPL.
-
-
Goetz, M.P.1
Suman, V.2
Ames, M.3
-
29
-
-
36349024762
-
Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypes
-
Schroth W, Antoniadou L, Fritz P, et al: Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypes. J Clin Oncol 25:5187-5193, 2007.
-
(2007)
J Clin Oncol
, vol.25
, pp. 5187-5193
-
-
Schroth, W.1
Antoniadou, L.2
Fritz, P.3
-
30
-
-
43649090742
-
Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy
-
Kiyotani K, Mushiroda T, Sasa M, et al: Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy. Cancer Sci 99:995-999, 2008.
-
(2008)
Cancer Sci
, vol.99
, pp. 995-999
-
-
Kiyotani, K.1
Mushiroda, T.2
Sasa, M.3
-
31
-
-
47749105202
-
Association between CYP2D6 *10 genotype and survival of breast cancer patients receiving tamoxifen treatment
-
Xu Y, Sun Y, Yao L, et al: Association between CYP2D6 *10 genotype and survival of breast cancer patients receiving tamoxifen treatment. Ann Oncol 19:1423-1429, 2008.
-
(2008)
Ann Oncol
, vol.19
, pp. 1423-1429
-
-
Xu, Y.1
Sun, Y.2
Yao, L.3
-
32
-
-
74249090424
-
Pharmacogenetic (CYP2D6) and gene expression profiles (HOXB13/IL17BR and molecular grade index) for prediction of adjuvant endocrine therapy benefit in the ABCSG 8 trial (abstract 57)
-
Goetz MP, Ames M, Gnant M, et al: Pharmacogenetic (CYP2D6) and gene expression profiles (HOXB13/IL17BR and molecular grade index) for prediction of adjuvant endocrine therapy benefit in the ABCSG 8 trial (abstract 57). Cancer Res 69(suppl), 2009.
-
(2009)
Cancer Res
, vol.69
, Issue.SUPPL.
-
-
Goetz, M.P.1
Ames, M.2
Gnant, M.3
-
33
-
-
74249095324
-
-
Ramon y Cahal T, Altes A, Pare L, et al: Impact of CYP2D6 polymorphisms in tamoxifen adjuvant breast cancer treatment. Breast Cancer Res Treat (epub February 3, 2009).
-
Ramon y Cahal T, Altes A, Pare L, et al: Impact of CYP2D6 polymorphisms in tamoxifen adjuvant breast cancer treatment. Breast Cancer Res Treat (epub February 3, 2009).
-
-
-
-
34
-
-
34548532227
-
Clinical implications of CYP2D6 genotypes predictive of tamoxifen pharmacokinetics in metastatic breast cancer
-
Lim HS, Ju Lee H, Seok Lee K, et al: Clinical implications of CYP2D6 genotypes predictive of tamoxifen pharmacokinetics in metastatic breast cancer. J Clin Oncol 25:3837-3845, 2007.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3837-3845
-
-
Lim, H.S.1
Ju Lee, H.2
Seok Lee, K.3
-
35
-
-
33747045564
-
-
Bonanni B, Macis D, Maisonneuve P, et al: Polymorphism in the CYP2D6 tamoxifen-metabolizing gene influences clinical effect but not hot flashes: Data from the Italian Tamoxifen Trial. J Clin Oncol 24:3708-3709; author reply 3709, 2006.
-
Bonanni B, Macis D, Maisonneuve P, et al: Polymorphism in the CYP2D6 tamoxifen-metabolizing gene influences clinical effect but not hot flashes: Data from the Italian Tamoxifen Trial. J Clin Oncol 24:3708-3709; author reply 3709, 2006.
-
-
-
-
36
-
-
29144491089
-
Genotype of metabolic enzymes and the benefit of tamoxifen in postmenopausal breast cancer patients
-
Wegman P, Vainikka L, Stal O, et al: Genotype of metabolic enzymes and the benefit of tamoxifen in postmenopausal breast cancer patients. Breast Cancer Res 7:R284-R290, 2005.
-
(2005)
Breast Cancer Res
, vol.7
-
-
Wegman, P.1
Vainikka, L.2
Stal, O.3
-
37
-
-
21344467511
-
Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients
-
Nowell SA, Ahn J, Rae JM, et al: Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients. Breast Cancer Res Treat 91:249-258, 2005.
-
(2005)
Breast Cancer Res Treat
, vol.91
, pp. 249-258
-
-
Nowell, S.A.1
Ahn, J.2
Rae, J.M.3
-
38
-
-
61449171134
-
Genetic polymorphisms of CYP2D6 10 and CYP2C19 2, 3 are not associated with prognosis, endometrial thickness, or bone mineral density in Japanese breast cancer patients treated with adjuvant tamoxifen
-
Okishiro M, Taguchi T, Jin Kim S, et al: Genetic polymorphisms of CYP2D6 10 and CYP2C19 2, 3 are not associated with prognosis, endometrial thickness, or bone mineral density in Japanese breast cancer patients treated with adjuvant tamoxifen. Cancer 115:952-961, 2009.
-
(2009)
Cancer
, vol.115
, pp. 952-961
-
-
Okishiro, M.1
Taguchi, T.2
Jin Kim, S.3
-
39
-
-
74549184178
-
Risk of breast cancer recurrence in women initiating tamoxifen with CYP2D6 inhibitors (abstract CRA508)
-
Aubert RE, Stanek EJ, Yao J, et al: Risk of breast cancer recurrence in women initiating tamoxifen with CYP2D6 inhibitors (abstract CRA508). J Clin Oncol 27(18S), 2009.
-
(2009)
J Clin Oncol
, vol.27
, Issue.18 S
-
-
Aubert, R.E.1
Stanek, E.J.2
Yao, J.3
-
40
-
-
74249111710
-
Concomitant CYP2D6 inhibitor use and tamoxifen adherence in early stage breast cancer: A pharmaco-epidemiological study (CRA509)
-
Dezentjé V, Van Blijderveen NJ, Gelderblom H, et al: Concomitant CYP2D6 inhibitor use and tamoxifen adherence in early stage breast cancer: A pharmaco-epidemiological study (CRA509). J Clin Oncol 27(18S), 2009.
-
(2009)
J Clin Oncol
, vol.27
, Issue.18 S
-
-
Dezentjé, V.1
Van Blijderveen, N.J.2
Gelderblom, H.3
-
41
-
-
33745347897
-
Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: Implication for optimization of breast cancer treatment
-
Borges S, Desta Z, Li L, et al: Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: Implication for optimization of breast cancer treatment. Clin Pharmacol Ther 80:61-74, 2006.
-
(2006)
Clin Pharmacol Ther
, vol.80
, pp. 61-74
-
-
Borges, S.1
Desta, Z.2
Li, L.3
-
42
-
-
70349575970
-
Association between CYP2D6 genotype and tamoxifen-induced hot flashes in a prospective cohort
-
Lynn Henry N, Rae JM, Li L, et al: Association between CYP2D6 genotype and tamoxifen-induced hot flashes in a prospective cohort. Breast Cancer Res Treat 117:571-575, 2009.
-
(2009)
Breast Cancer Res Treat
, vol.117
, pp. 571-575
-
-
Lynn Henry, N.1
Rae, J.M.2
Li, L.3
-
43
-
-
52449134044
-
Cytochrome P450 2D6 activity predicts adherence to tamoxifen therapy (abstract)
-
Rae J, Sikora MJ, Henry NL. Cytochrome P450 2D6 activity predicts adherence to tamoxifen therapy (abstract). Breast Cancer Res Treat 106(suppl 1):S21, 2007.
-
(2007)
Breast Cancer Res Treat
, vol.106
, Issue.SUPPL. 1
-
-
Rae, J.1
Sikora, M.J.2
Henry, N.L.3
-
44
-
-
44049098379
-
Pharmacogenomic variation of CYP2D6 and the choice of optimal adjuvant endocrine therapy for postmenopausal breast cancer: A modeling analysis
-
Punglia RS, Burstein HJ, Winer EP, et al: Pharmacogenomic variation of CYP2D6 and the choice of optimal adjuvant endocrine therapy for postmenopausal breast cancer: A modeling analysis. J Natl Cancer Inst 100:642-648, 2008.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 642-648
-
-
Punglia, R.S.1
Burstein, H.J.2
Winer, E.P.3
-
45
-
-
34248208754
-
Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer
-
Wegman P, Elingarami S, Carstensen J, et al: Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer. Breast Cancer Res 9(1):R7, 2007.
-
(2007)
Breast Cancer Res
, vol.9
, Issue.1
-
-
Wegman, P.1
Elingarami, S.2
Carstensen, J.3
-
46
-
-
53249086540
-
Impaired tamoxifen metabolism reduces survival in familial breast cancer patients
-
Newman WG, Hadfield KD, Latif A, et al: Impaired tamoxifen metabolism reduces survival in familial breast cancer patients. Clin Cancer Res 14:5913-5918, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5913-5918
-
-
Newman, W.G.1
Hadfield, K.D.2
Latif, A.3
-
47
-
-
4243063941
-
Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: Prominent roles for CYP3A and CYP2D6
-
Desta Z, Ward BA, Soukhova NV, et al: Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6. J Pharmacol Exp Ther 310:1062-1075, 2004.
-
(2004)
J Pharmacol Exp Ther
, vol.310
, pp. 1062-1075
-
-
Desta, Z.1
Ward, B.A.2
Soukhova, N.V.3
|