Rapid, sensitive and selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of topically applied azithromycin in rabbit conjunctiva tissues

Journal of Pharmaceutical and Biomedical Analysis

Volumn 52, Issue 1, 2010, Pages 99-104

  Shen, Yan ^a   Yin, Chun ^a   Su, Mengxiang ^a   Tu, Jiasheng ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Azithromycin; Conjunctiva; Liquid chromatography tandem mass spectrometry; Pharmacokinetic

Indexed keywords

ACETIC ACID; AMMONIUM ACETATE; AZITHROMYCIN; METHANOL; ROXITHROMYCIN;

ACCURACY; ANIMAL TISSUE; ARTICLE; CONJUNCTIVA; CONTROLLED STUDY; DRUG DETERMINATION; ELUTION; LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROCESS DEVELOPMENT; QUADRUPOLE MASS SPECTROMETRY; QUANTITATIVE ANALYSIS; RABBIT; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-BACTERIAL AGENTS; AZITHROMYCIN; BUFFERS; CALIBRATION; CHROMATOGRAPHY, LIQUID; CONJUNCTIVA; DRUG STABILITY; OBSERVATION; RABBITS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 74249111361     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.12.001     Document Type: Article

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