Cyclooxygenase-1 mediates the immediate corticosterone response to peripheral immune challenge induced by lipopolysaccharide

Neuroscience Letters

Volumn 470, Issue 1, 2010, Pages 10-12

  Elander, Louise ^a   Ruud, Johan ^a   Korotkova, Marina ^b   Jakobsson, Per Johan ^b   Blomqvist, Anders ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Corticosterone; Cyclooxygenase; Hypothalamus pituitary adrenal axis; Lipopolysaccharide; Mouse

Indexed keywords

5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; BACTERIUM LIPOPOLYSACCHARIDE; CORTICOSTERONE; CYCLOOXYGENASE 1; ISOPROTEIN; STRESS HORMONE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; GENE DELETION; GENETIC CODE; GENOTYPE; HORMONE INHIBITION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; WILD TYPE;

ADMINISTRATION, ORAL; ANIMALS; CORTICOSTERONE; CYCLOOXYGENASE 1; CYCLOOXYGENASE INHIBITORS; INFLAMMATION; LIPOPOLYSACCHARIDES; MICE; MICE, KNOCKOUT; PYRAZOLES; TIME FACTORS;

EID: 74149087004     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.12.036     Document Type: Article

References (19)

1. Besedovsky H., del Rey A., Sorkin E., and Dinarello C.A. Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science 233 (1986) 652-654
2. Ek M., Engblom D., Saha S., Blomqvist A., Jakobsson P.J., and Ericsson-Dahlstrand A. Inflammatory response: pathway across the blood-brain barrier. Nature 410 (2001) 430-431
3. Elander L., Engstrom L., Ruud J., Mackerlova L., Jakobsson P.J., Engblom D., Nilsberth C., and Blomqvist A. Inducible prostaglandin E2 synthesis interacts in a temporally supplementary sequence with constitutive prostaglandin-synthesizing enzymes in creating the hypothalamic-pituitary-adrenal axis response to immune challenge. J. Neurosci. 29 (2009) 1404-1413
4. Gao W., Schmidtko A., Wobst I., Lu R., Angioni C., and Geisslinger G. Prostaglandin D2 produced by hematopoietic prostaglandin D synthase contributes to LPS-induced fever. J. Physiol. Pharmacol. 60 (2009) 145-150
5. Garcia-Bueno B., Serrats J., and Sawchenko P.E. Cerebrovascular cyclooxygenase-1 expression, regulation, and role in hypothalamic-pituitary-adrenal axis activation by inflammatory stimuli. J. Neurosci. 29 (2009) 12970-12981
6. Jakobsson P.J., Thoren S., Morgenstern R., and Samuelsson B. Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 7220-7225
7. Lacroix S., and Rivest S. Effect of acute systemic inflammatory response and cytokines on the transcription of the genes encoding cyclooxygenase enzymes (COX-1 and COX-2) in the rat brain. J. Neurochem. 70 (1998) 452-466
8. Langenbach R., Morham S.G., Tiano H.F., Loftin C.D., Ghanayem B.I., Chulada P.C., Mahler J.F., Davis B.J., and Lee C.A. Disruption of the mouse cyclooxygenase 1 gene. Characteristics of the mutant and areas of future study. Adv. Exp. Med. Biol. 407 (1997) 87-92
9. Langenbach R., Morham S.G., Tiano H.F., Loftin C.D., Ghanayem B.I., Chulada P.C., Mahler J.F., Lee C.A., Goulding E.H., Kluckman K.D., Kim H.S., and Smithies O. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell 83 (1995) 483-492
10. Matsuoka Y., Furuyashiki T., Bito H., Ushikubi F., Tanaka Y., Kobayashi T., Muro S., Satoh N., Kayahara T., Higashi M., Mizoguchi A., Shichi H., Fukuda Y., Nakao K., and Narumiya S. Impaired adrenocorticotropic hormone response to bacterial endotoxin in mice deficient in prostaglandin E receptor EP1 and EP3 subtypes. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 4132-4137
11. McCoy J.G., Matta S.G., and Sharp B.M. Prostaglandins mediate the ACTH response to interleukin-1-beta instilled into the hypothalamic median eminence. Neuroendocrinology 60 (1994) 426-435
12. Murakami M., Nakashima K., Kamei D., Masuda S., Ishikawa Y., Ishii T., Ohmiya Y., Watanabe K., and Kudo I. Cellular prostaglandin E2 production by membrane-bound prostaglandin E synthase-2 via both cyclooxygenases-1 and -2. J. Biol. Chem. 278 (2003) 37937-37947
13. Ogorochi T., Ujihara M., and Narumiya S. Purification and properties of prostaglandin H-E isomerase from the cytosol of human brain: identification as anionic forms of glutathione S-transferase. J. Neurochem. 48 (1987) 900-909
14. Smith C.J., Zhang Y., Koboldt C.M., Muhammad J., Zweifel B.S., Shaffer A., Talley J.J., Masferrer J.L., Seibert K., and Isakson P.C. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 13313-13318
15. Ueno R., Narumiya S., Ogorochi T., Nakayama T., Ishikawa Y., and Hayaishi O. Role of prostaglandin D2 in the hypothermia of rats caused by bacterial lipopolysaccharide. Proc. Natl. Acad. Sci. U.S.A. 79 (1982) 6093-6097
16. Watanabe K., Kurihara K., Tokunaga Y., and Hayaishi O. Two types of microsomal prostaglandin E synthase: glutathione-dependent and -independent prostaglandin E synthases. Biochem. Biophys. Res. Commun. 235 (1997) 148-152
17. Watts A.G. Glucocorticoid regulation of peptide genes in neuroendocrine CRH neurons: a complexity beyond negative feedback. Front. Neuroendocrinol. 26 (2005) 109-130
18. Zhang J., Fujii S., Wu Z., Hashioka S., Tanaka Y., Shiratsuchi A., Nakanishi Y., and Nakanishi H. Involvement of COX-1 and up-regulated prostaglandin E synthases in phosphatidylserine liposome-induced prostaglandin E2 production by microglia. J. Neuroimmunol. 172 (2006) 112-120
19. Zhang Y.H., Lu J., Elmquist J.K., and Saper C.B. Specific roles of cyclooxygenase-1 and cyclooxygenase-2 in lipopolysaccharide-induced fever and Fos expression in rat brain. J. Comp. Neurol. 463 (2003) 3-12