-
1
-
-
0027912932
-
PGH synthase isoenzyme selectivity:the potential for safer nonsteroidal antiinflammatory drugs
-
DeWitt, D.L. , Meade, E.A., and Smith, W.L., 1993, PGH synthase isoenzyme selectivity:the potential for safer nonsteroidal antiinflammatory drugs, Amer. J. Medicine 95 (suppl. 12A):40S.
-
(1993)
Amer. J. Medicine
, vol.95
, Issue.SUPPL. 12A
-
-
DeWitt, D.L.1
Meade, E.A.2
Smith, W.L.3
-
2
-
-
0028818913
-
Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
-
Dinchuk, J.E., Car, B.C., Focht, R.J., Johnston, J.J., Jaffee, B.D., Covington, M.B., Contel, N.R., Eng, V.M., Collins, R.J., Czernak, P.M., Gorry, S.A., and Trzaskos, J.M., 1995, Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II, Nature 378:406.
-
(1995)
Nature
, vol.378
, pp. 406
-
-
Dinchuk, J.E.1
Car, B.C.2
Focht, R.J.3
Johnston, J.J.4
Jaffee, B.D.5
Covington, M.B.6
Contel, N.R.7
Eng, V.M.8
Collins, R.J.9
Czernak, P.M.10
Gorry, S.A.11
Trzaskos, J.M.12
-
3
-
-
0025909387
-
Human platelet/erythroleukemia cell prostaglandin G/H synthase:cDNA cloning, expression, and gene chromosomal assignment
-
Funk, C.D., Funk, L.B., Kennedy, M.E., Pong, A.S., and Fitzgerald, G.A., 1991, Human platelet/erythroleukemia cell prostaglandin G/H synthase:cDNA cloning, expression, and gene chromosomal assignment, FASEB J. 5:2304.
-
(1991)
FASEB J.
, vol.5
, pp. 2304
-
-
Funk, C.D.1
Funk, L.B.2
Kennedy, M.E.3
Pong, A.S.4
Fitzgerald, G.A.5
-
4
-
-
0027993458
-
Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
-
Eberhart, C.E., Coffey, R.J., Radhika, A., Giardiello, F.M., Ferrenbach, S., and DuBois, R.N., 1994, Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas, Gastroenterology 107:1183.
-
(1994)
Gastroenterology
, vol.107
, pp. 1183
-
-
Eberhart, C.E.1
Coffey, R.J.2
Radhika, A.3
Giardiello, F.M.4
Ferrenbach, S.5
DuBois, R.N.6
-
5
-
-
0022608686
-
Development and validation of an alternative dermal sensitization test:the mouse ear swelling test (MEST)
-
Gad, S.C., Dunn, B.J., Dobbs, D.W., Reilly, C., and Walsh, R.D., 1986, Development and validation of an alternative dermal sensitization test:the mouse ear swelling test (MEST), Toxicol. Appl. Pharmacol. 84:93.
-
(1986)
Toxicol. Appl. Pharmacol.
, vol.84
, pp. 93
-
-
Gad, S.C.1
Dunn, B.J.2
Dobbs, D.W.3
Reilly, C.4
Walsh, R.D.5
-
6
-
-
0028923919
-
Breast cancer and NSAID use:heterogeneity of effect in a case-control study
-
Harris, R.E., Namboodiri, K. Stellman, S.D., and Wynder, E.L., 1995, Breast cancer and NSAID use:heterogeneity of effect in a case-control study, Preventive Medicine 24:119.
-
(1995)
Preventive Medicine
, vol.24
, pp. 119
-
-
Harris, R.E.1
Namboodiri, K.2
Stellman, S.D.3
Wynder, E.L.4
-
7
-
-
0029008617
-
Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer
-
Kargman, S.L., Oneill, G.P., Vickers, P.J., Evans, J.F., Mancini, J.A., and Jothy, S., 1995, Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer, Cancer Res. 55:2556.
-
(1995)
Cancer Res.
, vol.55
, pp. 2556
-
-
Kargman, S.L.1
Oneill, G.P.2
Vickers, P.J.3
Evans, J.F.4
Mancini, J.A.5
Jothy, S.6
-
8
-
-
0028172885
-
Pregnancy maintainance and parturition:the role of prostaglandin in manipulating the immune and inflammatory response
-
Kelly, R.W., 1994, Pregnancy maintainance and parturition:the role of prostaglandin in manipulating the immune and inflammatory response, Endocrine Rev. 15:684.
-
(1994)
Endocrine Rev.
, vol.15
, pp. 684
-
-
Kelly, R.W.1
-
9
-
-
0025871150
-
TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
-
Kujubu, D.A., Fletcher, B.S., Varnum, B.C., Lim, R.W., and Herschman, H.R., 1991, TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue, J. Biol. Chem., 266:12866.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 12866
-
-
Kujubu, D.A.1
Fletcher, B.S.2
Varnum, B.C.3
Lim, R.W.4
Herschman, H.R.5
-
10
-
-
0028843881
-
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
-
Langenbach, R., Morham, S.G., Tiano, H.F., Loftin, C.D., Ghanayem, B.I., Chulada, P.C., Mahler, J.F., Lee, C.A., Goulding, E.H., Kluckman, K.D., Kim, H.S. and Smithies, O., 1995, Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration, Cell 83:483.
-
(1995)
Cell
, vol.83
, pp. 483
-
-
Langenbach, R.1
Morham, S.G.2
Tiano, H.F.3
Loftin, C.D.4
Ghanayem, B.I.5
Chulada, P.C.6
Mahler, J.F.7
Lee, C.A.8
Goulding, E.H.9
Kluckman, K.D.10
Kim, H.S.11
Smithies, O.12
-
11
-
-
0026761738
-
Aspirin and the potential role of prostaglandins in colon cancer
-
Marnett, L.J., 1992, Aspirin and the potential role of prostaglandins in colon cancer, Cancer Res. 52:5575.
-
(1992)
Cancer Res.
, vol.52
, pp. 5575
-
-
Marnett, L.J.1
-
12
-
-
0028322893
-
Selective inhibition of inducible cyclooxygenase-2 in vivo is antiinflammatory and nonulcerogenic
-
Masferrer, J.L., Zweifel, B.S., Manning, P.T., Hauser, S.D., Leahy, K.M., Smith, W.G., Isakson, P.C., and Seibert, K., 1994, Selective inhibition of inducible cyclooxygenase-2 in vivo is antiinflammatory and nonulcerogenic, Proc. Natl. Acad. Sci. USA 91:3228.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3228
-
-
Masferrer, J.L.1
Zweifel, B.S.2
Manning, P.T.3
Hauser, S.D.4
Leahy, K.M.5
Smith, W.G.6
Isakson, P.C.7
Seibert, K.8
-
13
-
-
0027237456
-
Chemoprevention of OH-BBN-induced bladder cancer in mice by piroxicam
-
Moon, R.C., Kelloff, G.J., Detrisac, C.J., Steele, V.E., Thomas, C.F., and Sigman, C.C., 1993, Chemoprevention of OH-BBN-induced bladder cancer in mice by piroxicam, Carcinogenesis 14:1487.
-
(1993)
Carcinogenesis
, vol.14
, pp. 1487
-
-
Moon, R.C.1
Kelloff, G.J.2
Detrisac, C.J.3
Steele, V.E.4
Thomas, C.F.5
Sigman, C.C.6
-
14
-
-
0028807498
-
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
-
Morham, S.G., Langenbach, R., Loftin, C.D., Tiano, H.F., Vouloumanos, N., Jennette, J.C., Mahler, J.F., Kluckman, K.D., Ledford, A., Lee, C.A., and Smithies, O., 1995, Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse, Cell 83:472.
-
(1995)
Cell
, vol.83
, pp. 472
-
-
Morham, S.G.1
Langenbach, R.2
Loftin, C.D.3
Tiano, H.F.4
Vouloumanos, N.5
Jennette, J.C.6
Mahler, J.F.7
Kluckman, K.D.8
Ledford, A.9
Lee, C.A.10
Smithies, O.11
-
15
-
-
0025015168
-
A dominant mutation that predisposes to intestional neoplasia in the mouse
-
Moser, A.R., Pitít, H.C. and Dove, W.F., 1990, A dominant mutation that predisposes to intestional neoplasia in the mouse, Science 247:322.
-
(1990)
Science
, vol.247
, pp. 322
-
-
Moser, A.R.1
Pitít, H.C.2
Dove, W.F.3
-
16
-
-
0028946520
-
Differential expression of prostaglandin H synthase isozymes during multistage carcinogenesis in mouse epidermis
-
Muller-Decker, K., Scholz, K., Marks, F., and Furstenberger, G., 1995, Differential expression of prostaglandin H synthase isozymes during multistage carcinogenesis in mouse epidermis, Mol. Carcinogen. 12:31.
-
(1995)
Mol. Carcinogen.
, vol.12
, pp. 31
-
-
Muller-Decker, K.1
Scholz, K.2
Marks, F.3
Furstenberger, G.4
-
17
-
-
0021957329
-
Prostaglandin and leukotriene synthesis in mouse ears inflamed by arachidonic acid
-
Opas, E.E., Bonney, R.J., and Humes, J.L., 1985, Prostaglandin and leukotriene synthesis in mouse ears inflamed by arachidonic acid, J. Invest. Dermatol. 84: 253.
-
(1985)
J. Invest. Dermatol.
, vol.84
, pp. 253
-
-
Opas, E.E.1
Bonney, R.J.2
Humes, J.L.3
-
18
-
-
0029088472
-
The effects of sulindac on colorectal proliferation and apoptosis in familial adenomatous polyposis
-
Pasricha, P.J., Bedi, A., O'Connor, K., Rashid, A., Aktar, A.J., Zahurak, M.L., Piantadosi, S., Hamilton, S.R. and Giardello, F.M., 1995, The effects of sulindac on colorectal proliferation and apoptosis in familial adenomatous polyposis, Gastroenterology 109:994.
-
(1995)
Gastroenterology
, vol.109
, pp. 994
-
-
Pasricha, P.J.1
Bedi, A.2
O'Connor, K.3
Rashid, A.4
Aktar, A.J.5
Zahurak, M.L.6
Piantadosi, S.7
Hamilton, S.R.8
Giardello, F.M.9
-
19
-
-
0028904461
-
Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent
-
Rao, C.V., Rivenson, A., Simi, B., Zang, E., Kelloff, G., Steele, V., and Reddy, B.S., 1995, Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent, Cancer Res. 55:1464.
-
(1995)
Cancer Res.
, vol.55
, pp. 1464
-
-
Rao, C.V.1
Rivenson, A.2
Simi, B.3
Zang, E.4
Kelloff, G.5
Steele, V.6
Reddy, B.S.7
-
20
-
-
0016774453
-
An intestinal disease produced experimentally by a prostaglandin deficiency
-
Robert, A., 1975, An intestinal disease produced experimentally by a prostaglandin deficiency, Gastroenterology 69: 1045.
-
(1975)
Gastroenterology
, vol.69
, pp. 1045
-
-
Robert, A.1
-
21
-
-
0027944075
-
Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain
-
Seibert, K., Zhang, Y., Leahy, K., Hauser, S., Masferrer, J., Perkins, W., Lee, L., and Isakson, P., 1994, Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain, Proc. Natl. Acad. Sci. USA 91:12013.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12013
-
-
Seibert, K.1
Zhang, Y.2
Leahy, K.3
Hauser, S.4
Masferrer, J.5
Perkins, W.6
Lee, L.7
Isakson, P.8
-
22
-
-
0026774117
-
Hormonal regulation of messenger ribonucleic acid encoding a novel isoform of prostaglandin endoperoxide H synthase in rat preovulatory follicles. Induction in vivo and in vitro
-
Sirois, J., Simmons, D.L., and Richards, J.S., 1992, Hormonal regulation of messenger ribonucleic acid encoding a novel isoform of prostaglandin endoperoxide H synthase in rat preovulatory follicles. Induction in vivo and in vitro, J. Biol. Chem. 267:11586.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 11586
-
-
Sirois, J.1
Simmons, D.L.2
Richards, J.S.3
-
23
-
-
0028892461
-
Identifying chemical carcinogens and assessing potential risk in short-term bioassays using transgenic mouse models
-
Tennant, R.W., French, J.E., and Spalding, J.W. , 1995, Identifying chemical carcinogens and assessing potential risk in short-term bioassays using transgenic mouse models, Envir. Health Pers. 103:942.
-
(1995)
Envir. Health Pers.
, vol.103
, pp. 942
-
-
Tennant, R.W.1
French, J.E.2
Spalding, J.W.3
-
24
-
-
84971043131
-
The placenta, prostaglandins and parturition:a review
-
Thorburn, G.D., 1991, The placenta, prostaglandins and parturition:a review, Reprod. Fertil. Dev. 3:277.
-
(1991)
Reprod. Fertil. Dev.
, vol.3
, pp. 277
-
-
Thorburn, G.D.1
-
25
-
-
0027512524
-
Aspirin use and risk of fatal cancer
-
Thun, M.J., Namboodiri, M.M., Calle, E.E., Flanders, W.D., and Heath, C.W.J., 1993, Aspirin use and risk of fatal cancer, Cancer Res. 53:1322.
-
(1993)
Cancer Res.
, vol.53
, pp. 1322
-
-
Thun, M.J.1
Namboodiri, M.M.2
Calle, E.E.3
Flanders, W.D.4
Heath, C.W.J.5
-
26
-
-
0028803728
-
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
-
Tsujii, M. and DuBois, R.N., 1995, Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2, Cell 83:493.
-
(1995)
Cell
, vol.83
, pp. 493
-
-
Tsujii, M.1
DuBois, R.N.2
-
27
-
-
0028044609
-
Pharmacology - Towards a better aspirin
-
Vane, J., 1994, Pharmacology - towards a better aspirin, Nature 367, 215.
-
(1994)
Nature
, vol.367
, pp. 215
-
-
Vane, J.1
-
28
-
-
0028323295
-
Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation
-
Vane, J.R., Mitchell, J.A., Appleton, I., Tomlinson, A., Bishop-Bailey, D., Croxtall, J., and Willoughby, D.A., 1994, Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation, Proc. Natl. Acad. Sci. USA 91:2046.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2046
-
-
Vane, J.R.1
Mitchell, J.A.2
Appleton, I.3
Tomlinson, A.4
Bishop-Bailey, D.5
Croxtall, J.6
Willoughby, D.A.7
|