Up-regulation of ferritin ubiquitination in skeletal muscle of transgenic rats bearing the G93A hmSOD1 gene mutation

Neuromuscular Disorders

Volumn 20, Issue 1, 2010, Pages 29-33

  Halon, Malgorzata ^a   Sielicka Dudzin, Alicja ^a   Wozniak, Michal ^a   Ziolkowski, Wiesław ^c   Nyka, Walenty ^a   Herbik, Magdalena ^b   Grieb, Pawel ^b   Figarski, Adam ^a   Antosiewicz, Jedrzej ^d  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

^b POLISH ACADEMY OF SCIENCES   (Poland)

^c GDANSK UNIVERSITY OF PHYSICAL EDUCATION AND SPORT   (Poland)

^d SWPS UNIVERSITY OF SOCIAL SCIENCES AND HUMANITIES   (Poland)

Author keywords

Iron; Oxidative stress; Ubiquitin

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; FERRITIN;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE MUTATION; IMMUNOPRECIPITATION; LEG MUSCLE; MALE; MUSCLE LEVEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN STRUCTURE; RAT; SKELETAL MUSCLE; TRANSGENIC RAT; UBIQUITINATION; UPREGULATION;

ANIMALS; COLORIMETRY; ELECTROPHORESIS; FERRITINS; HINDLIMB; IMMUNOPRECIPITATION; MALE; MUSCLE, SKELETAL; ORGAN SIZE; PROTEIN CARBONYLATION; RATS; RATS, SPRAGUE-DAWLEY; RATS, TRANSGENIC; SUPEROXIDE DISMUTASE; UBIQUITINATION; UP-REGULATION;

EID: 74149084491     PISSN: 09608966     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nmd.2009.08.014     Document Type: Article

References (26)

1. Turner B.J., and Talbot K. Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS. Prog Neurobiol 85 (2008) 94-134
2. Lino M.M., Schneider C., and Caroni P. Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease. J Neurosci 22 (2002) 4825-4832
3. Yamanaka K., Boillee S., Roberts E.A., Garcia M.L., McAlonis-Downes M., Mikse O.R., et al. Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice. Proc Natl Acad Sci USA 105 (2008) 7594-7599
4. Pramatarova A., Laganiere J., Roussel J., Brisebois K., and Rouleau G.A. Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment. J Neurosci 21 (2001) 3369-3374
5. Yamanaka K., Chun S.J., Boillee S., Fujimori-Tonou N., Yamashita H., Gutmann D.H., et al. Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis. Nat Neurosci 11 (2008) 251-253
6. Goodall E.F., Haque M.S., and Morrison K.E. Increased serum ferritin levels in amyotrophic lateral sclerosis (ALS) patients. J Neurol 255 (2008) 1652-1656
7. Mahoney D.J., Kaczor J.J., Bourgeois J., Yasuda N., and Tarnopolsky M.A. Oxidative stress and antioxidant enzyme upregulation in SOD1-G93A mouse skeletal muscle. Muscle Nerve 33 (2006) 809-816
8. Dobrowolny G., Aucello M., Rizzuto E., Beccafico S., Mammucari C., Bonconpagni S., et al. Skeletal muscle is a primary target of SOD1G93A-mediated toxicity. Cell Metab 8 (2008) 425-436
9. Qian S.Y., and Buettner G.R. Iron and dioxygen chemistry is an important route to initiation of biological free radical oxidations: an electron paramagnetic resonance spin trapping study. Free Radic Biol Med 26 (1999) 1447-1456
10. Sammarco M.C., Ditch S., Banerjee A., and Grabczyk E. Ferritin L and H subunits are differentially regulated on a post-transcriptional level. J Biol Chem 283 (2008) 4578-4587
11. Kasarskis E.J., Tandon L., Lovell M.A., and Ehmann W.D. Aluminum, calcium, and iron in the spinal cord of patients with sporadic amyotrophic lateral sclerosis using laser microprobe mass spectroscopy: a preliminary study. J Neurol Sci 130 (1995) 203-208
12. Jeong S.Y., Rathore K.I., Schulz K., Ponka P., Arosio P., and David S. Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis. J Neurosci 29 (2009) 610-619
13. Danzeisen R., Achsel T., Bederke U., Cozzolino M., Crosio C., Ferri A., et al. Superoxide dismutase 1 modulates expression of transferrin receptor. J Biol Inorg Chem 11 (2006) 489-498
14. Olsen M.K., Roberds S.L., Ellerbrock B.R., Fleck T.J., McKinley D.K., and Gurney M.E. Disease mechanisms revealed by transcription profiling in SOD1-G93A transgenic mouse spinal cord. Ann Neurol 50 (2001) 730-740
15. Howland D.S., Liu J., She Y., Goad B., Maragakis N.J., Kim B., et al. Focal loss of the glutamate transporter EAAT 2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). Proc Natl Acad Sci USA 99 (2002) 1604-1609
16. Herbik M.A., Chrapusta S.J., Kowalczyk A., and Grieb P. Maintenance of the rat transgenic model of familial amyotrophic lateral sclerosis expressing human SOD1G93A mutation. Folia Neuropathol 44 (2006) 149-153
17. Levine R.L., Garland D., Oliver C.N., Amici A., Climent I., Lenz A.G., et al. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 186 (1990) 464-478
18. David G., Nguyen K., and Barrett E.F. Early vulnerability to ischemia/reperfusion injury in motor terminals innervating fast muscles of SOD1-G93A mice. Exp Neurol 204 (2007) 411-420
19. Lexell J., Jarvis J.C., Currie J., Downham D.Y., and Salmons S. Fibre type composition of rabbit tibialis anterior and extensor digitorum longus muscles. J Anat 185 Pt 1 (1994) 95-101
20. Lexell J., Jarvis J., Downham D., and Salmons S. Quantitative morphology of stimulation-induced damage in rabbit fast-twitch skeletal muscles. Cell Tissue Res 269 (1992) 195-204
21. Kruszewski M. Labile iron pool: the main determinant of cellular response to oxidative stress. Mutat Res 531 (2003) 81-92
22. Carri M.T., Ferri A., Cozzolino M., Calabrese L., and Rotilio G. Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals. Brain Res Bull 61 (2003) 365-374
23. De Domenico I., Vaughn M.B., Li L., Bagley D., Musci G., Ward D.M., et al. Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome. EMBO J 25 (2006) 5396-5404
24. Miller L.L., Miller S.C., Torti S.V., Tsuji Y., and Torti F.M. Iron-independent induction of ferritin H chain by tumor necrosis factor. Proc Natl Acad Sci USA 88 (1991) 4946-4950
25. Antosiewicz J., Ziolkowski W., Kaczor J.J., and Herman-Antosiewicz A. Tumor necrosis factor-alpha-induced reactive oxygen species formation is mediated by JNK1-dependent ferritin degradation and elevation of labile iron pool. Free Radic Biol Med 43 (2007) 265-270
26. Holasek S.S., Wengenack T.M., Kandimalla K.K., Montano C., Gregor D.M., Curran G.L., et al. Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice. Brain Res 1045 (2005) 185-198