Gene and stem cell therapy in ischemic stroke

Cell Transplantation

Volumn 18, Issue 9, 2009, Pages 999-1002

  Yamashita, Toru ^a   Deguchi, Kentaro ^a   Nagotani, Shoko ^a   Kamiya, Tatsushi ^a   Abe, Koji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Adenoviral vector; Cerebral ischemia; Free radical; Neural stem cells; Scaffold

Indexed keywords

ADENOVIRUS VECTOR; AZELNIDIPINE; BILIVERDIN; CALCIUM CHANNEL BLOCKING AGENT; DISUFENTON SODIUM; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NORPHENAZONE;

ANTIOXIDANT ACTIVITY; BRAIN DAMAGE; BRAIN EDEMA; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELL PROTECTION; CEREBROVASCULAR ACCIDENT; CONFERENCE PAPER; DEGRADATION; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; HUMAN; HYPERTENSION; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; STROKE; SUBVENTRICULAR ZONE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ANIMALS; ANTIOXIDANTS; AZETIDINECARBOXYLIC ACID; BILIVERDINE; BRAIN ISCHEMIA; DIHYDROPYRIDINES; DISEASE MODELS, ANIMAL; GENE THERAPY; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HUMANS; MODELS, BIOLOGICAL; NEUROPROTECTIVE AGENTS; STEM CELL TRANSPLANTATION;

ANIMALIA;

EID: 74049151610     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368909X471233     Document Type: Conference Paper

References (27)

1. Abe, K. Therapeutic potential of neurotrophic factors and neural stem cells against ischemic brain injury. J. Cereb. Blood Flow Metab. 20(10):1393-1408; 2000.
2. Abe, K.; Yuki, S.; Kogure, K. Strong attenuation of ischemic and postischemic brain edema in rats by a novel free radical scavenger. Stroke 19(4):480-485; 1988.
3. Altman, J. Autoradiographic and histological studies of postnatal neurogenesis. IV. Cell proliferation and migration in the anterior forebrain, with special reference to persisting neurogenesis in the olfactory bulb. J. Comp. Neurol. 137(4):433-457; 1969.
4. Chan, P. H. Reactive oxygen radicals in signaling and damage in the ischemic brain. J. Cereb. Blood Flow Metab. 21(1):2-14; 2001.
5. Deguchi, K.; Hayashi, T.; Nagotani, S.; Sehara, Y.; Zhang, H.; Tsuchiya, A.; Ohta, Y.; Tomiyama, K.; Morimoto, N.; Miyazaki, M.; Huh, N. H.; Nakao, A.; Kamiya, T.; Abe, K. Reduction of cerebral infarction in rats by biliverdin associated with amelioration of oxidative stress. Brain Res. 1188:1-8; 2008.
6. Deguchi, K.; Tsuru, K.; Hayashi, T.; Takaishi, M.; Nagahara, M.; Nagotani, S.; Sehara, Y.; Jin, G.; Zhang, H.; Hayakawa, S.; Shoji, M.; Miyazaki, M.; Osaka, A.; Huh, N. H.; Abe, K. Implantation of a new porous gelatin-silox ane hybrid into a brain lesion as a potential scaffold for tissue regeneration. J. Cereb. Blood Flow Metab. 26(10):1263-1273; 2006.
7. Doetsch, F.; Caille, I.; Lim, D. A.; Garcia-Verdugo, J. M.; Alvarez-Buylla, A. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97(6):703-716; 1999.
8. Hayashi, J.; Takagi, Y.; Fukuda, H.; Imazato, T.; Nishimura, M.; Fujimoto, M.; Takahashi, J.; Hashimoto, N.; Nozaki, K. Primate embryonic stem cell-derived neuronal progenitors transplanted into ischemic brain. J. Cereb. Blood Flow Metab. 26(7):906-914; 2006.
9. Hou, S.; Xu, Q.; Tian, W.; Cui, F.; Cai, Q.; Ma, J.; Lee, I. S. The repair of brain lesion by implantation of hyaluronic acid hydrogels modified with laminin. J. Neurosci. Methods 148(1):60-70; 2005.
10. Hsiao, G.; Lee, J. J.; Chen, Y. C.; Lin, J. H.; Shen, M. Y.; Lin, K. H.; Chou, D. S.; Sheu, J. R. Neuroprotective effects of PMC, a potent alpha-tocopherol derivative, in brain ischemia-reperfusion: Reduced neutrophil activation and anti-oxidant actions. Biochem. Pharmacol. 73(5):682-693; 2007.
11. Kataoka, K.; Suzuki, Y.; Kitada, M.; Ohnishi, K.; Suzuki, K.; Tanihara, M.; Ide, C.; Endo, K.; Nishimura, Y. Alginate, a bioresorbable material derived from brown seaweed, enhances elongation of amputated axons of spinal cord in infant rats. J. Biomed. Mater. Res. 54(3):373-384; 2001.
12. Kitagawa, H.; Hayashi, T.; Mitsumoto, Y.; Koga, N.; Itoyama, Y.; Abe, K. Reduction of ischemic brain injury by topical application of glial cell line-derived neurotrophic factor after permanent middle cerebral artery occlusion in rats. Stroke 29(7):1417-1422; 1998.
13. Kitagawa, H.; Sasaki, C.; Sakai, K.; Mori, A.; Mitsumoto, Y.; Mori, T.; Fukuchi, Y.; Setoguchi, Y.; Abe, K. Adenovirus-mediated gene transfer of glial cell line-derived neurotrophic factor prevents ischemic brain injury after transient middle cerebral artery occlusion in rats. J. Cereb. Blood Flow Metab. 19(12):1336-1344; 1999.
14. Kuroda, S.; Tsuchidate, R.; Smith, M. L.; Maples, K. R.; Siesjo, B. K. Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat. J. Cereb. Blood Flow Metab. 19(7):778-787; 1999.
15. Lees, K. R.; Zivin, J. A.; Ashwood, T.; Davalos, A.; Davis, S. M.; Diener, H. C.; Grotta, J.; Lyden, P.; Shuaib, A.; Hardemark, H. G.; Wasiewski, W. W. NXY-059 for acute ischemic stroke. N. Engl. J. Med. 354(6):588-600; 2006.
16. Li, L.; Wu, W.; Lin, L. F.; Lei, M.; Oppenheim, R. W.; Houenou, L. J. Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor. Proc. Natl. Acad. Sci. USA 92(21):9771-9775; 1995.
17. Lois, C.; Alvarez-Buylla, A. Long-distance neuronal migration in the adult mammalian brain. Science 264(5162):1145-1148; 1994.
18. Lukic-Panin, V.; Kamiya, T.; Zhang, H.; Hayashi, T.; Tsuchiya, A.; Sehara, Y.; Deguchi, K.; Yamashita, T.; Abe, K. Prevention of neuronal damage by calcium channel blockers with antioxidative effects after transient focal ischemia in rats. Brain Res. 1176:143-150; 2007.
19. Nakatomi, H.; Kuriu, T.; Okabe, S.; Yamamoto, S.; Hatano, O.; Kawahara, N.; Tamura, A.; Kirino, T.; Nakafuku, M. Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors. Cell 110(4):429-441; 2002.
20. Ren, L.; Tsuru, K.; Hayakawa, S.; Osaka, A. Novel approach to fabricate porous gelatin-siloxane hybrids for bone tissue engineering. Biomaterials 23(24):4765-4773; 2002.
21. Shuaib, A.; Lees, K. R.; Lyden, P.; Grotta, J.; Davalos, A.; Davis, S. M.; Diener, H. C.; Ashwood, T.; Wasiewski, W. W.; Emeribe, U. NXY-059 for the treatment of acute ischemic stroke. N. Engl. J. Med. 357(6):562-571; 2007.
22. Stocker, R. Antioxidant activities of bile pigments. Antioxid. Redox Signal 6(5):841-849; 2004.
23. Teramoto, T.; Qiu, J.; Plumier, J. C.; Moskowitz, M. A. EGF amplifies the replacement of parvalbumin-expressing striatal interneurons after ischemia. J. Clin. Invest. 111(8):1125-1132; 2003.
24. The Edaravone Acute Brain Infarction Study Group. Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters. Cerebrovasc. Dis. 15(3):222-229; 2003.
25. Tian, W. M.; Hou, S. P.; Ma, J.; Zhang, C. L.; Xu, Q. Y.; Lee, I. S.; Li, H. D.; Spector, M.; Cui, F. Z. Hyaluronic acid-poly-D-lysine-based three-dimensional hydrogel for traumatic brain injury. Tissue Eng. 11(3-4):513-525; 2005.
26. Yamashita, T.; Ninomiya, M.; Hernandez Acosta, P.; Garcia-Verdugo, J. M.; Sunabori, T.; Sakaguchi, M.; Adachi, K.; Kojima, T.; Hirota, Y.; Kawase, T.; Araki, N.; Abe, K.; Okano, H.; Sawamoto, K. Subventricular zone-derived neuroblasts migrate and differentiate into mature neurons in the post-stroke adult striatum. J. Neurosci. 26(24):6627-6636; 2006.
27. Yao, K.; Ina, Y.; Nagashima, K.; Ohmori, K.; Ohno, T. Antioxidant effects of calcium antagonists in rat brain homogenates. Biol. Pharm. Bull. 23(6):766-769; 2000.