IKK inhibitor bay 11-7082 induces necroptotic cell death in precursor-B acute lymphoblastic leukaemic blasts

British Journal of Haematology

Volumn 148, Issue 3, 2010, Pages 487-490

  Meng, Xiangbing ^a,b   Martinez, Marina A ^a   Raymond Stintz, Mary A ^a   Winter, Stuart S ^a,b   Wilson, Bridget S ^a,b  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

Acute lymphoblastic leukaemia; IKK; Necroptosis

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; 4 (2 AMINOETHYLAMINO) 1,8 DIMETHYLIMIDAZO[1,2 A]QUINOXALINE; 6 CHLORO 8 NICOTINAMIDO BETA CARBOLINE; PARTHENOLIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; B LYMPHOCYTE; BLAST CELL; CELL DEATH; CELL VIABILITY; ENZYME INHIBITION; HUMAN; LETTER; LYMPHOBLAST; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TREATMENT RESPONSE;

ANTINEOPLASTIC AGENTS; CELL DEATH; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; NF-KAPPA B; NITRILES; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; SULFONES; TUMOR CELLS, CULTURED;

EID: 74049142002     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2009.07988.x     Document Type: Letter

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