Mapping genetic influences on the corticospinal motor system in humans

Neuroscience

Volumn 164, Issue 1, 2009, Pages 156-163

  Cheeran, B J ^a   Ritter, C ^b   Rothwell, J C ^a   Siebner, H R ^c  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF KIEL   (Germany)

^c HVIDOVRE HOSPITAL   (Denmark)

Author keywords

Brain derived neurotrophic factor; Corticospinal system; Diffusion tensor imaging; Neurodegenerative disease; Synaptic plasticity; Transcranial magnetic stimulation

Indexed keywords

ANIMAL; GENETICS; HISTOLOGY; HUMAN; MOTOR ACTIVITY; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; NERVE CELL PLASTICITY; PATHOPHYSIOLOGY; PHYSIOLOGY; PYRAMIDAL TRACT; REVIEW;

ANIMALS; HUMANS; MOTOR ACTIVITY; MOTOR SKILLS; MOVEMENT DISORDERS; NEURONAL PLASTICITY; PYRAMIDAL TRACTS;

EID: 74049136566     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.01.054     Document Type: Review

References (57)

1. Andersen P.M., Borasio G.D., Dengler R., Hardiman O., Kollewe K., Leigh P.N., Pradat P.F., Silani V., Tomik B. Good practice in the management of amyotrophic lateral sclerosis: clinical guidelines. An evidence-based review with good practice points. EALSC Working Group. Amyotroph Lateral Scler 2007, 8:195-213.
2. Beaulieu C. The basis of anisotropic water diffusion in the nervous system-a technical review. NMR Biomed 2002, 15:435-455.
3. Bressman S.B. Dystonia update. Clin Neuropharmacol 2000, 23:239-251.
4. Brown C.E., Li P., Boyd J.D., Delaney K.R., Murphy T.H. Extensive turnover of dendritic spines and vascular remodeling in cortical tissues recovering from stroke. J Neurosci 2007, 27:4101-4109.
5. Brugman F., Scheffer H., Wokke J.H., Nillesen W.M., de Visser M., Aronica E., Veldink J.H., van den Berg L.H. Paraplegin mutations in sporadic adult-onset upper motor neuron syndromes. Neurology 2008, 71(19):1500-1505.
6. Cheeran B., Talelli P., Mori F., Koch G., Suppa A., Edwards M., Houlden H., Bhatia K., Greenwood R., Rothwell J.C. A common polymorphism in the brain derived neurotrophic factor gene (BDNF) modulates human cortical plasticity and the response to rTMS. J Physiol 2008, 586(Pt 23):5717-5725.
7. Chen Q., Lui S., Wang J.G., Ou-Yang L., Zhou D., Burgunder J.M., Gong Q.Y., Shang H.F. Diffusion tensor imaging of two unrelated Chinese men with hereditary spastic paraplegia associated with thin corpus callosum. Neurosci Lett 2008, 441:21-24.
8. Dalla Torre di Sanguinetto S.A., Dasen J.S., Arber S. Transcriptional mechanisms controlling motor neuron diversity and connectivity. Curr Opin Neurobiol 2008, 18:36-43.
9. Dasen J.S., De Camilli A., Wang B., Tucker P.W., Jessell T.M. Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1. Cell 2008, 134:304-316.
10. Dasen J.S., Tice B.C., Brenner-Morton S., Jessell T.M. A Hox regulatory network establishes motor neuron pool identity and target-muscle connectivity. Cell 2005, 123:477-491.
11. Dengler R., von Neuhoff N., Bufler J., Krampfl K., Peschel T., Grosskreutz J. Amyotrophic lateral sclerosis: new developments in diagnostic markers. Neurodegener Dis 2005, 2:177-184.
12. Depienne C., Stevanin G., Brice A., Durr A. Hereditary spastic paraplegias: an update. Curr Opin Neurol 2007, 20:674-680.
13. Dreha-Kulaczewski S., Dechent P., Helms G., Frahm J., Gartner J., Brockmann K. Cerebral metabolic and structural alterations in hereditary spastic paraplegia with thin corpus callosum assessed by MRS and DTI. Neuroradiology 2006, 48:893-898.
14. Edwards M.J., Huang Y.Z., Mir P., Rothwell J.C., Bhatia K.P. Abnormalities in motor cortical plasticity differentiate manifesting and nonmanifesting DYT1 carriers. Mov Disord 2006, 21:2181-2186.
15. Egan M.F., Kojima M., Callicott J.H., Goldberg T.E., Kolachana B.S., Bertolino A., Zaitsev E., Gold B., Goldman D., Dean M., Lu B., Weinberger D.R. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 2003, 112:257-269.
16. Ellis C.M., Simmons A., Jones D.K., Bland J., Dawson J.M., Horsfield M.A., Williams S.C., Leigh P.N. Diffusion tensor MRI assesses corticospinal tract damage in ALS. Neurology 1999, 53:1051-1058.
17. Foltynie T., Cheeran B., Williams-Gray C.H., Edwards M.J., Schneider S., Weinberger D.R., Rothwell J., Barker R.A., Bhatia K.P. BDNF val66met influences time to onset of levodopa-induced dyskinesia in Parkinson's disease. J Neurol Neurosurg Psychiatry 2009, 80(2):141-144.
18. Fritsch B., Reis J., Martinowich K., Cohen L.G., Lu B. Effects of direct currents on long term potentiation in the mouse primary motor cortex in vitro, a possible role of brain derived neurotrophic factor (BDNF). Soc Neurosci Abstr 2008, 39:5.
19. Graham J.M., Papadakis N., Evans J., Widjaja E., Romanowski C.A., Paley M.N., Wallis L.I., Wilkinson I.D., Shaw P.J., Griffiths P.D. Diffusion tensor imaging for the assessment of upper motor neuron integrity in ALS. Neurology 2004, 63:2111-2119.
20. Hariri A.R., Goldberg T.E., Mattay V.S., Kolachana B.S., Callicott J.H., Egan M.F., Weinberger D.R. Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance. J Neurosci 2003, 23:6690-6694.
21. Hong Y.H., Lee K.W., Sung J.J., Chang K.H., Song I.C. Diffusion tensor MRI as a diagnostic tool of upper motor neuron involvement in amyotrophic lateral sclerosis. J Neurol Sci 2004, 227:73-78.
22. Huang Y.Z., Edwards M.J., Rounis E., Bhatia K.P., Rothwell J.C. Theta burst stimulation of the human motor cortex. Neuron 2005, 45:201-206.
23. Iwata N.K., Aoki S., Okabe S., Arai N., Terao Y., Kwak S., Abe O., Kanazawa I., Tsuji S., Ugawa Y. Evaluation of corticospinal tracts in ALS with diffusion tensor MRI and brainstem stimulation. Neurology 2008, 70:528-532.
24. Jacob S., Finsterbusch J., Weishaupt J.H., Khorram-Sefat D., Frahm J., Ehrenreich H. Diffusion tensor imaging for long-term follow-up of corticospinal tract degeneration in amyotrophic lateral sclerosis. Neuroradiology 2003, 45:598-600.
25. James P.A., Talbot K. The molecular genetics of non-ALS motor neuron diseases. Biochim Biophys Acta 2006, 1762:986-1000.
26. Jankovic J. Can peripheral trauma induce dystonia and other movement disorders?. Yes! Mov Disord 2001, 16:7-12.
27. Johansen-Berg H., Behrens T.E. Just pretty pictures?. What diffusion tractography can add in clinical neuroscience. Curr Opin Neurol 2006, 19:379-385.
28. Kleim J.A., Chan S., Pringle E., Schallert K., Procaccio V., Jimenez R., Cramer S.C. BDNF val66met polymorphism is associated with modified experience-dependent plasticity in human motor cortex. Nat Neurosci 2006, 9:735-737.
29. Klein T.A., Neumann J., Reuter M., Hennig J., von Cramon D.Y., Ullsperger M. Genetically determined differences in learning from errors. Science 2007, 318:1642-1645.
30. Kramer E.R., Knott L., Su F., Dessaud E., Krull C.E., Helmbacher F., Klein R. Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb. Neuron 2006, 50:35-47.
31. Liebetanz D., Nitsche M.A., Tergau F., Paulus W. Pharmacological approach to the mechanisms of transcranial DC-stimulation-induced after-effects of human motor cortex excitability. Brain 2002, 125:2238-2247.
32. Liepert J., Bauder H., Wolfgang H.R., Miltner W.H., Taub E., Weiller C. Treatment-induced cortical reorganization after stroke in humans. Stroke 2000, 31:1210-1216.
33. Linazasoro G. New ideas on the origin of L-DOPA-induced dyskinesias: age, genes and neural plasticity. Trends Pharmacol Sci 2005, 26:391-397.
34. Lu B. Pro-region of neurotrophins: role in synaptic modulation. Neuron 2003, 39:735-738.
35. Marsden C.D., Sheehy M.P. Writer's cramp. Trends Neurosci 1990, 13:148-153.
36. Martin J.H., Friel K.M., Salimi I., Chakrabarty S. Activity- and use-dependent plasticity of the developing corticospinal system. Neurosci Biobehav Rev 2007, 31:1125-1135.
37. Ng M.C., Ho J.T., Ho S.L., Lee R., Li G., Cheng T.S., Song Y.Q., Ho P.W., Fong G.C., Mak W., Chan K.H., Li L.S., Luk K.D., Hu Y., Ramsden D.B., Leong L.L. Abnormal diffusion tensor in nonsymptomatic familial amyotrophic lateral sclerosis with a causative superoxide dismutase 1 mutation. J Magn Reson Imaging 2008, 27:8-13.
38. Nudo R.J. Mechanisms for recovery of motor function following cortical damage. Curr Opin Neurobiol 2006, 16:638-644.
39. Nudo R.J., Milliken G.W., Jenkins W.M., Merzenich M.M. Use-dependent alterations of movement representations in primary motor cortex of adult squirrel monkeys. J Neurosci 1996, 16:785-807.
40. Pagani E., Agosta F., Rocca M.A., Caputo D., Filippi M. Voxel-based analysis derived from fractional anisotropy images of white matter volume changes with aging. Neuroimage 2008, 41:657-667.
41. Pezawas L., Verchinski B.A., Mattay V.S., Callicott J.H., Kolachana B.S., Straub R.E., Egan M.F., Meyer-Lindenberg A., Weinberger D.R. The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology. J Neurosci 2004, 24:10099-10102.
42. Picconi B., Centonze D., Hakansson K., Bernardi G., Greengard P., Fisone G., Cenci M.A., Calabresi P. Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia. Nat Neurosci 2003, 6:501-506.
43. Quartarone A., Siebner H.R., Rothwell J.C. Task-specific hand dystonia: can too much plasticity be bad for you?. Trends Neurosci 2006, 29:192-199.
44. Rascol O., Brooks D.J., Korczyn A.D., De Deyn P.P., Clarke C.E., Lang A.E. A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa. 056 Study Group. N Engl J Med 2000, 342:1484-1491.
45. Rosen D.R., Siddique T., Patterson D., Figlewicz D.A., Sapp P., Hentati A., Donaldson D., Goto J., O'Regan J.P., Deng H.X., et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993, 362:59-62.
46. Sach M., Winkler G., Glauche V., Liepert J., Heimbach B., Koch M.A., Buchel C., Weiller C. Diffusion tensor MRI of early upper motor neuron involvement in amyotrophic lateral sclerosis. Brain 2004, 127:340-350.
47. Sanes J.R., Lichtman J.W. Can molecules explain long-term potentiation?. Nat Neurosci 1999, 2:597-604.
48. Sendtner M., Carroll P., Holtmann B., Hughes R.A., Thoenen H. Ciliary neurotrophic factor. J Neurobiol 1994, 25:1436-1453.
49. Siebner H.R., Lang N., Rizzo V., Nitsche M.A., Paulus W., Lemon R.N., Rothwell J.C. Preconditioning of low-frequency repetitive transcranial magnetic stimulation with transcranial direct current stimulation: evidence for homeostatic plasticity in the human motor cortex. J Neurosci 2004, 24:3379-3385.
50. Siebner H.R., Rothwell J. Transcranial magnetic stimulation: new insights into representational cortical plasticity. Exp Brain Res 2003, 148:1-16.
51. Stefan K., Kunesch E., Cohen L.G., Benecke R., Classen J. Induction of plasticity in the human motor cortex by paired associative stimulation. Brain 2000, 123(Pt 3):572-584.
52. Svenson I.K., Ashley-Koch A.E., Gaskell P.C., Riney T.J., Cumming W.J., Kingston H.M., Hogan E.L., Boustany R.M., Vance J.M., Nance M.A., Pericak-Vance M.A., Marchuk D.A. Identification and expression analysis of spastin gene mutations in hereditary spastic paraplegia. Am J Hum Genet 2001, 68:1077-1085.
53. Thickbroom G.W. Transcranial magnetic stimulation and synaptic plasticity: experimental framework and human models. Exp Brain Res 2007, 180:583-593.
54. Warnecke T., Duning T., Schwan A., Lohmann H., Epplen J.T., Young P. A novel form of autosomal recessive hereditary spastic paraplegia caused by a new SPG7 mutation. Neurology 2007, 69:368-375.
55. Wolters A., Sandbrink F., Schlottmann A., Kunesch E., Stefan K., Cohen L.G., Benecke R., Classen J. A temporally asymmetric Hebbian rule governing plasticity in the human motor cortex. J Neurophysiol 2003, 89:2339-2345.
56. Woo N.H., Teng H.K., Siao C.J., Chiaruttini C., Pang P.T., Milner T.A., Hempstead B.L., Lu B. Activation of p75NTR by proBDNF facilitates hippocampal long-term depression. Nat Neurosci 2005, 8:1069-1077.
57. Ziemann U., Paulus W., Nitsche M.A., Pascual-Leone A., Byblow W.D., Berardelli A., Siebner H.R., Classen J., Cohen L.G., Rothwell J.C. Consensus: motor cortex plasticity protocols. Brain Stimulation 2008, 1:164-182.