Novel antitumor effect of carboplatin delivered by intracerebral microinfusion in a rat malignant glioma model

Neurologia Medico-Chirurgica

Volumn 49, Issue 12, 2009, Pages 572-579

  Tange, Yuichi ^a,b   Miyazaki, Masahiro ^a   Iwata, Junko ^a   Aiko, Yasuhisa ^a   Sakamoto, Shinichi ^a   Mori, Kentaro ^a  

^a JUNTENDO UNIVERSITY   (Japan)

^b JUNTENDO UNIVERSITY NERIMA HOSPITAL   (Japan)

Author keywords

Brain tumor; Carboplatin; Chemotherapy; Intracerebral microinfusion; Rat model

Indexed keywords

CARBOPLATIN; EVANS BLUE; GADOLINIUM; GLUCOSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD VESSEL PERMEABILITY; CANCER SURVIVAL; CANCER TISSUE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG INFUSION; DRUG MEGADOSE; GLIOBLASTOMA; HISTOPATHOLOGY; LOW DRUG DOSE; MALE; MICROINFUSION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OSMOTIC MINI PUMP; RAT; TUMOR NECROSIS; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS; BRAIN EDEMA; BRAIN NEOPLASMS; CARBOPLATIN; CELL LINE, TUMOR; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EVANS BLUE; GLIOMA; INFUSION PUMPS, IMPLANTABLE; INJECTIONS, INTRAVENOUS; MAGNETIC RESONANCE IMAGING; MALE; MICROINJECTIONS; NEOPLASM INVASIVENESS; RATS; RATS, INBRED F344; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 74049112925     PISSN: 04708105     EISSN: 13498029     Source Type: Journal    
DOI: 10.2176/nmc.49.572     Document Type: Article

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