-
1
-
-
54149090275
-
-
World Health Organization Geneva: World Health Organization
-
World Health Organization. The Global Burden of Disease 2004 Update. Geneva: World Health Organization 2008.
-
(2008)
The Global Burden of Disease 2004 Update
-
-
-
2
-
-
47649121828
-
Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia
-
Zhang W, Otsuka T, Sugo N, Ardeshiri A, Alhadid YK, Iliff JJ, DeBarber AE, Koop DR, Alkayed NJ. Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia. Stroke. 2008;39: 2073-2078.
-
(2008)
Stroke
, vol.39
, pp. 2073-2078
-
-
Zhang, W.1
Otsuka, T.2
Sugo, N.3
Ardeshiri, A.4
Alhadid, Y.K.5
Iliff, J.J.6
Debarber, A.E.7
Koop, D.R.8
Alkayed, N.J.9
-
3
-
-
1642477082
-
Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia [Abstract]
-
Otsuka T, Sugo N, Koehler R, Hurn P, Traystman R, Alkayed NJ. Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia [Abstract]. Stroke. 2003;34:301.
-
(2003)
Stroke
, vol.34
, pp. 301
-
-
Otsuka, T.1
Sugo, N.2
Koehler, R.3
Hurn, P.4
Traystman, R.5
Alkayed, N.J.6
-
4
-
-
0030358016
-
Actions of epox-ygenase metabolites on the preglomerular vasculature
-
Imig JD, Navar LG, Roman RJ, Reddy KK, Falck JR. Actions of epox-ygenase metabolites on the preglomerular vasculature. J Am Soc Nephrol. 1996;7:2364-2370.
-
(1996)
J Am Soc Nephrol
, vol.7
, pp. 2364-2370
-
-
Imig, J.D.1
Navar, L.G.2
Roman, R.J.3
Reddy, K.K.4
Falck, J.R.5
-
5
-
-
38549145416
-
Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population
-
Zhang L, Ding H, Yan J, Hui R, Wang W, Kissling GE, Zeldin DC, Wang DW. Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population. Pharma-cogenet Genomics. 2008;18:45-51.
-
(2008)
Pharma-cogenet Genomics
, vol.18
, pp. 45-51
-
-
Zhang, L.1
Ding, H.2
Yan, J.3
Hui, R.4
Wang, W.5
Kissling, G.E.6
Zeldin, D.C.7
Wang, D.W.8
-
6
-
-
26444506849
-
The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke
-
Fornage M, Lee CR, Doris PA, Bray MS, Heiss G, Zeldin DC, Boer-winkle E. The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke. Hum Mol Genet. 2005;14:2829-2837.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2829-2837
-
-
Fornage, M.1
Lee, C.R.2
Doris, P.A.3
Bray, M.S.4
Heiss, G.5
Zeldin, D.C.6
Boer-Winkle, E.7
-
7
-
-
0035965327
-
Epoxygenase pathways of arachidonic acid metabolism
-
Zeldin DC. Epoxygenase pathways of arachidonic acid metabolism. J Biol Chem. 2001;276:36059-36062.
-
(2001)
J Biol Chem
, vol.276
, pp. 36059-36062
-
-
Zeldin, D.C.1
-
8
-
-
13844316739
-
Epoxide hydrolases: Mechanisms, inhibitor designs, and biological roles
-
Morisseau C, Hammock BD. Epoxide hydrolases: mechanisms, inhibitor designs, and biological roles. Annu Rev Pharmacol Toxicol. 2005;45: 311-333.
-
(2005)
Annu Rev Pharmacol Toxicol
, vol.45
, pp. 311-333
-
-
Morisseau, C.1
Hammock, B.D.2
-
9
-
-
0042343719
-
Polymorphisms in human soluble epoxide hydrolase
-
Przybyla-Zawislak BD, Srivastava PK, Vazquez-Matias J, Mohrenweiser HW, Maxwell JE, Hammock BD, Bradbury JA, Enayetallah AE, Zeldin DC, Grant DF. Polymorphisms in human soluble epoxide hydrolase. Mol Pharmacol. 2003;64:482-490.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 482-490
-
-
Przybyla-Zawislak, B.D.1
Srivastava, P.K.2
Vazquez-Matias, J.3
Mohrenweiser, H.W.4
Maxwell, J.E.5
Hammock, B.D.6
Bradbury, J.A.7
Enayetallah, A.E.8
Zeldin, D.C.9
Grant, D.F.10
-
10
-
-
0034666150
-
Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms
-
Sandberg M, Hassett C, Adman ET, Meijer J, Omiecinski CJ. Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms. J Biol Chem. 2000;275:28873-28881.
-
(2000)
J Biol Chem
, vol.275
, pp. 28873-28881
-
-
Sandberg, M.1
Hassett, C.2
Adman, E.T.3
Meijer, J.4
Omiecinski, C.J.5
-
11
-
-
2942579253
-
Polymorphisms in human soluble epoxide hydrolase: Effects on enzyme activity, enzyme stability, and quaternary structure
-
Srivastava PK, Sharma VK, Kalonia DS, Grant DF. Polymorphisms in human soluble epoxide hydrolase: effects on enzyme activity, enzyme stability, and quaternary structure. Arch Biochem Biophys. 2004;427: 164-169.
-
(2004)
Arch Biochem Biophys
, vol.427
, pp. 164-169
-
-
Srivastava, P.K.1
Sharma, V.K.2
Kalonia, D.S.3
Grant, D.F.4
-
12
-
-
10744225519
-
Soluble epoxide hydrolase variant (Glu287Arg) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterol-emia: Intrafamilial association study in an eight-generation hyperlipid-emic kindred
-
Sato K, Emi M, Ezura Y, Fujita Y, Takada D, Ishigami T, Umemura S, Xin Y, Wu LL, Larrinaga-Shum S, Stephenson SH, Hunt SC, Hopkins PN. Soluble epoxide hydrolase variant (Glu287Arg) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterol-emia: intrafamilial association study in an eight-generation hyperlipid-emic kindred. J Hum Genet. 2004;49:29-34.
-
(2004)
J Hum Genet
, vol.49
, pp. 29-34
-
-
Sato, K.1
Emi, M.2
Ezura, Y.3
Fujita, Y.4
Takada, D.5
Ishigami, T.6
Umemura, S.7
Xin, Y.8
Wu, L.L.9
Larrinaga-Shum, S.10
Stephenson, S.H.11
Hunt, S.C.12
Hopkins, P.N.13
-
13
-
-
14644429730
-
Epoxide hydrolases: Their roles and interactions with lipid metabolism
-
Newman JW, Morisseau C, Hammock BD. Epoxide hydrolases: their roles and interactions with lipid metabolism. Prog Lipid Res. 2005; 44:1-51.
-
(2005)
Prog Lipid Res
, vol.44
, pp. 1-51
-
-
Newman, J.W.1
Morisseau, C.2
Hammock, B.D.3
-
14
-
-
44449110695
-
Genetic variation in soluble epoxide hydrolase (EPHX2) is associated with an increased risk of is-chemic stroke in white Europeans
-
Gschwendtner A, Ripke S, Freilinger T, Lichtner P, Muller-Myhsok B, Wichmann HE, Meitinger T, Dichgans M. Genetic variation in soluble epoxide hydrolase (EPHX2) is associated with an increased risk of is-chemic stroke in white Europeans. Stroke. 2008;39:1593-1596.
-
(2008)
Stroke
, vol.39
, pp. 1593-1596
-
-
Gschwendtner, A.1
Ripke, S.2
Freilinger, T.3
Lichtner, P.4
Muller-Myhsok, B.5
Wichmann, H.E.6
Meitinger, T.7
Dichgans, M.8
-
15
-
-
34447511196
-
Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
-
Nordestgaard BG, Benn M, Schnohr P, Tybjaerg-Hansen A. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA. 2007;298:299-308.
-
(2007)
JAMA
, vol.298
, pp. 299-308
-
-
Nordestgaard, B.G.1
Benn, M.2
Schnohr, P.3
Tybjaerg-Hansen, A.4
-
16
-
-
0036554781
-
Coronary heart disease risk factors ranked by importance for the individual and community. A 21 year follow-up of 12 000 men and women from the Copenhagen City Heart Study
-
Schnohr P, Jensen JS, Scharling H, Nordestgaard BG. Coronary heart disease risk factors ranked by importance for the individual and community. A 21 year follow-up of 12 000 men and women from The Copenhagen City Heart Study. Eur Heart J. 2002;23:620-626.
-
(2002)
Eur Heart J
, vol.23
, pp. 620-626
-
-
Schnohr, P.1
Jensen, J.S.2
Scharling, H.3
Nordestgaard, B.G.4
-
17
-
-
44649140474
-
Association of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease
-
Frikke-Schmidt R, Nordestgaard BG, Stene MC, Sethi AA, Remaley AT, Schnohr P, Grande P, Tybjaerg-Hansen A. Association of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease. JAMA. 2008;299:2524-2532.
-
(2008)
JAMA
, vol.299
, pp. 2524-2532
-
-
Frikke-Schmidt, R.1
Nordestgaard, B.G.2
Stene, M.C.3
Sethi, A.A.4
Remaley, A.T.5
Schnohr, P.6
Grande, P.7
Tybjaerg-Hansen, A.8
-
18
-
-
0030803017
-
ACE gene polymorphism as a risk factor for ischemic cerebrovascular disease
-
Agerholm-Larsen B, Tybjaerg-Hansen A, Frikke-Schmidt R, Gronholdt ML, Jensen G, Nordestgaard BG. ACE gene polymorphism as a risk factor for ischemic cerebrovascular disease. Ann Intern Med. 1997;127: 346-355.
-
(1997)
Ann Intern Med
, vol.127
, pp. 346-355
-
-
Agerholm-Larsen, B.1
Tybjaerg-Hansen, A.2
Frikke-Schmidt, R.3
Gronholdt, M.L.4
Jensen, G.5
Nordestgaard, B.G.6
-
19
-
-
55249087635
-
Genetically elevated C-reactive protein and ischemic vascular disease
-
Zacho J, Tybjaerg-Hansen A, Jensen JS, Grande P, Sillesen H, Nor-destgaard BG. Genetically elevated C-reactive protein and ischemic vascular disease. N Engl J Med. 2008;359:1897-1908.
-
(2008)
N Engl J Med
, vol.359
, pp. 1897-1908
-
-
Zacho, J.1
Tybjaerg-Hansen, A.2
Jensen, J.S.3
Grande, P.4
Sillesen, H.5
Nor-Destgaard, B.G.6
-
20
-
-
56149115017
-
Nonfasting triglycerides and risk of ischemic stroke in the general population
-
Freiberg JJ, Tybjaerg-Hansen A, Jensen JS, Nordestgaard BG. Nonfasting triglycerides and risk of ischemic stroke in the general population. JAMA. 2008;300:2142-2152.
-
(2008)
JAMA
, vol.300
, pp. 2142-2152
-
-
Freiberg, J.J.1
Tybjaerg-Hansen, A.2
Jensen, J.S.3
Nordestgaard, B.G.4
-
21
-
-
55549111247
-
Superoxide dismutase 3 polymorphism associated with reduced lung function in two large populations
-
Dahl M, Bowler RP, Juul K, Crapo JD, Levy S, Nordestgaard BG. Superoxide dismutase 3 polymorphism associated with reduced lung function in two large populations. Am J Respir Crit Care Med. 2008;178: 906-912.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 906-912
-
-
Dahl, M.1
Bowler, R.P.2
Juul, K.3
Crapo, J.D.4
Levy, S.5
Nordestgaard, B.G.6
-
22
-
-
33745918021
-
Development of a high-throughput screen for soluble epoxide hydrolase inhibition
-
Wolf NM, Morisseau C, Jones PD, Hock B, Hammock BD. Development of a high-throughput screen for soluble epoxide hydrolase inhibition. Anal Biochem. 2006;355:71-80.
-
(2006)
Anal Biochem
, vol.355
, pp. 71-80
-
-
Wolf, N.M.1
Morisseau, C.2
Jones, P.D.3
Hock, B.4
Hammock, B.D.5
-
23
-
-
1642458135
-
Polymorphism of the Soluble Epoxide Hydrolase Is Associated with Coronary Artery Calcification in African-American Subjects: The Coronary Artery Risk Development in Young Adults (CARDIA) Study
-
DOI 10.1161/01.CIR.0000109487.46725.02
-
Fornage M, Boerwinkle E, Doris PA, Jacobs D, Liu K, Wong ND. Polymorphism of the soluble epoxide hydrolase is associated with coronary artery calcification in African-American subjects: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Circulation. 2004;109:335-339. (Pubitemid 38133900)
-
(2004)
Circulation
, vol.109
, Issue.3
, pp. 335-339
-
-
Fornage, M.1
Boerwinkle, E.2
Doris, P.A.3
Jacobs, D.4
Liu, K.5
Wong, N.D.6
-
24
-
-
45249124328
-
Genetic analysis of the soluble epoxide hydrolase gene, EPHX2, in subclinical cardiovascular disease in the Diabetes Heart Study
-
Burdon KP, Lehtinen AB, Langefeld CD, Carr JJ, Rich SS, Freedman BI, Herrington D, Bowden DW. Genetic analysis of the soluble epoxide hydrolase gene, EPHX2, in subclinical cardiovascular disease in the Diabetes Heart Study. Diab Vasc Dis Res. 2008;5:128-134.
-
(2008)
Diab Vasc Dis Res
, vol.5
, pp. 128-134
-
-
Burdon, K.P.1
Lehtinen, A.B.2
Langefeld, C.D.3
Carr, J.J.4
Rich, S.S.5
Freedman, B.I.6
Herrington, D.7
Bowden, D.W.8
-
25
-
-
33745222033
-
Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study
-
DOI 10.1093/hmg/ddl085
-
Lee CR, North KE, Bray MS, Fornage M, Seubert JM, Newman JW, Hammock BD, Couper DJ, Heiss G, Zeldin DC. Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study. Hum Mol Genet. 2006;15:1640-1649. (Pubitemid 43904830)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.10
, pp. 1640-1649
-
-
Lee, C.R.1
North, K.E.2
Bray, M.S.3
Fornage, M.4
Seubert, J.M.5
Newman, J.W.6
Hammock, B.D.7
Couper, D.J.8
Heiss, G.9
Zeldin, D.C.10
-
26
-
-
33845535114
-
Sequence variation in the soluble epoxide hydrolase gene and subclinical coronary atherosclerosis: Interaction with cigarette smoking
-
Wei Q, Doris PA, Pollizotto MV, Boerwinkle E, Jacobs DR Jr, Siscovick DS, Fornage M. Sequence variation in the soluble epoxide hydrolase gene and subclinical coronary atherosclerosis: interaction with cigarette smoking. Atherosclerosis. 2007;190:26-34.
-
(2007)
Atherosclerosis
, vol.190
, pp. 26-34
-
-
Wei, Q.1
Doris, P.A.2
Pollizotto, M.V.3
Boerwinkle, E.4
Jacobs Jr., D.R.5
Siscovick, D.S.6
Fornage, M.7
-
27
-
-
0034711488
-
Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids
-
Yu Z, Xu F, Huse LM, Morisseau C, Draper AJ, Newman JW, Parker C, Graham L, Engler MM, Hammock BD, Zeldin DC, Kroetz DL. Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circ Res. 2000;87:992-998. (Pubitemid 30949215)
-
(2000)
Circulation Research
, vol.87
, Issue.11
, pp. 992-998
-
-
Yu, Z.1
Xu, F.2
Huse, L.M.3
Morisseau, C.4
Draper, A.J.5
Newman, J.W.6
Parker, C.7
Graham, L.8
Engler, M.M.9
Hammock, B.D.10
Zeldin, D.C.11
Kroetz, D.L.12
-
28
-
-
25844438367
-
The prevalence of CYP2C8, 2C9, 2J2, and soluble epoxide hydrolase polymorphisms in African Americans with hypertension
-
Dreisbach AW, Japa S, Sigel A, Parenti MB, Hess AE, Srinouanprachanh SL, Rettie AE, Kim H, Farin FM, Hamm LL, Lertora JJ. The prevalence of CYP2C8, 2C9, 2J2, and soluble epoxide hydrolase polymorphisms in African Americans with hypertension. Am J Hypertens. 2005;18: 1276-1281.
-
(2005)
Am J Hypertens
, vol.18
, pp. 1276-1281
-
-
Dreisbach, A.W.1
Japa, S.2
Sigel, A.3
Parenti, M.B.4
Hess, A.E.5
Srinouanprachanh, S.L.6
Rettie, A.E.7
Kim, H.8
Farin, F.M.9
Hamm, L.L.10
Lertora, J.J.11
|