메뉴 건너뛰기




Volumn 5, Issue , 2009, Pages 873-882

Comparison of prasugrel and clopidogrel in patients with acute coronary syndrome undergoing percutaneous coronary intervention

Author keywords

Acute coronary syndrome; Clopidogrel; Percutaneous coronary intervention; Prasugrel

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; HYPERICUM PERFORATUM EXTRACT; KETOCONAZOLE; PRASUGREL; PROTON PUMP INHIBITOR; RIFAMPICIN; VASODILATOR STIMULATED PHOSPHOPROTEIN;

EID: 74049104107     PISSN: 11766344     EISSN: 11782048     Source Type: Journal    
DOI: 10.2147/vhrm.s5699     Document Type: Review
Times cited : (39)

References (80)
  • 1
    • 37249068049 scopus 로고    scopus 로고
    • Platelet activation and atherothrombosis
    • Davi G, Patrono C. Platelet activation and atherothrombosis. N Engl J Med. 2007;357(24):2482-2494.
    • (2007) N Engl J Med , vol.357 , Issue.24 , pp. 2482-2494
    • Davi, G.1    Patrono, C.2
  • 2
    • 38049169354 scopus 로고    scopus 로고
    • Focused Update of the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: 2007 Writing Group to Review New Evidence and Update the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention, Writing on Behalf of the 2005 Writing Committee
    • King SB 3rd, Smith SC Jr, Hirshfeld JW Jr, et al. 2007 Focused Update of the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: 2007 Writing Group to Review New Evidence and Update the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention, Writing on Behalf of the 2005 Writing Committee. Circulation. 2008;117(2):261-295.
    • (2007) Circulation , vol.117 , Issue.2 , pp. 261-295
    • King 3rd, S.B.1    Smith Jr, S.C.2    Hirshfeld Jr, J.W.3
  • 3
    • 0028120906 scopus 로고
    • Collaborative overview of randomised trials of antiplatelet therapy - I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Antiplatelet Trialists' Collaboration
    • Collaborative overview of randomised trials of antiplatelet therapy - I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Antiplatelet Trialists' Collaboration. BMJ. 1994;308(6921):81-106.
    • (1994) BMJ , vol.308 , Issue.6921 , pp. 81-106
  • 4
    • 33747088257 scopus 로고    scopus 로고
    • Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: A 700-patient study of aspirin resistance
    • Frelinger AL 3rd, Furman MI, Linden MD, et al. Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance. Circulation. 2006;113(25):2888-2896.
    • (2006) Circulation , vol.113 , Issue.25 , pp. 2888-2896
    • Frelinger 3rd, A.L.1    Furman, M.I.2    Linden, M.D.3
  • 5
    • 33646761285 scopus 로고    scopus 로고
    • Aspirin resistance detected with aggregometry cannot be explained by cyclooxygenase activity: Involvement of other signaling pathway(s) in cardiovascular events of aspirin-treated patients
    • Ohmori T, Yatomi Y, Nonaka T, et al. Aspirin resistance detected with aggregometry cannot be explained by cyclooxygenase activity: involvement of other signaling pathway(s) in cardiovascular events of aspirin-treated patients. J Thromb Haemost. 2006;4(6):1271-1278.
    • (2006) J Thromb Haemost , vol.4 , Issue.6 , pp. 1271-1278
    • Ohmori, T.1    Yatomi, Y.2    Nonaka, T.3
  • 6
    • 33144479358 scopus 로고    scopus 로고
    • Regulation of platelet functions by P2 receptors
    • Gachet C. Regulation of platelet functions by P2 receptors. Annu Rev Pharmacol Toxicol. 2006;46:277-300.
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 277-300
    • Gachet, C.1
  • 7
    • 42249102617 scopus 로고    scopus 로고
    • P2 receptors, platelet function and pharmacological implications
    • Gachet C. P2 receptors, platelet function and pharmacological implications. Thromb Haemost. 2008;99(3):466-472.
    • (2008) Thromb Haemost , vol.99 , Issue.3 , pp. 466-472
    • Gachet, C.1
  • 8
    • 0034911702 scopus 로고    scopus 로고
    • ADP receptors of platelets and their inhibition
    • Gachet C. ADP receptors of platelets and their inhibition. Thromb Haemost. 2001;86(1):222-232.
    • (2001) Thromb Haemost , vol.86 , Issue.1 , pp. 222-232
    • Gachet, C.1
  • 9
    • 33645282277 scopus 로고    scopus 로고
    • The platelet P2 receptors in arterial thrombosis
    • Gachet C, Léon C, Hechler B. The platelet P2 receptors in arterial thrombosis. Blood Cells Mol Dis. 2006;36(2):223-227.
    • (2006) Blood Cells Mol Dis , vol.36 , Issue.2 , pp. 223-227
    • Gachet, C.1    Léon, C.2    Hechler, B.3
  • 11
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med. 2001;345(7):494-502.
    • (2001) N Engl J Med , vol.345 , Issue.7 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3    Chrolavicius, S.4    Tognoni, G.5    Fox, K.K.6
  • 13
    • 40749094082 scopus 로고    scopus 로고
    • Effects of the proton pump inhibitor lansoprazole on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel
    • Small DS, Farid NA, Payne CD, et al. Effects of the proton pump inhibitor lansoprazole on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel. J Clin Pharmacol. 2008;48(4):475-484.
    • (2008) J Clin Pharmacol , vol.48 , Issue.4 , pp. 475-484
    • Small, D.S.1    Farid, N.A.2    Payne, C.D.3
  • 14
    • 50249184573 scopus 로고    scopus 로고
    • Effect of ranitidine on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel
    • Small DS, Farid NA, Li YG, et al. Effect of ranitidine on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel. Curr Med Res Opin. 2008;24(8):2251-2257.
    • (2008) Curr Med Res Opin , vol.24 , Issue.8 , pp. 2251-2257
    • Small, D.S.1    Farid, N.A.2    Li, Y.G.3
  • 15
    • 0033678468 scopus 로고    scopus 로고
    • Identification and biological activity of the active metabolite of clopidogrel
    • Savi P, Pereillo JM, Uzabiaga MF, et al. Identification and biological activity of the active metabolite of clopidogrel. Thromb Haemost. 2000;84(5):891-896.
    • (2000) Thromb Haemost , vol.84 , Issue.5 , pp. 891-896
    • Savi, P.1    Pereillo, J.M.2    Uzabiaga, M.F.3
  • 16
    • 0028083293 scopus 로고
    • The antiaggregating activity of clopidogrel is due to a metabolic activation by the hepatic cytochrome P450-1 A
    • Savi P, Combalbert J, Gaich C, et al. The antiaggregating activity of clopidogrel is due to a metabolic activation by the hepatic cytochrome P450-1 A. Thromb Haemost. 1994;72(2):313-317.
    • (1994) Thromb Haemost , vol.72 , Issue.2 , pp. 313-317
    • Savi, P.1    Combalbert, J.2    Gaich, C.3
  • 18
    • 34247181997 scopus 로고    scopus 로고
    • In vitro metabolism of antiplatelet agent clopidogrel: Cytochrome P450 isoforms responsible for two oxidation steps involved in active metabolite formation
    • Kurihara A HK, Kazui M, Ishizuka T, Farid NA, Ikeda T. In vitro metabolism of antiplatelet agent clopidogrel: cytochrome P450 isoforms responsible for two oxidation steps involved in active metabolite formation. Drug Metab Rev. 2005;37(Suppl 2):99.
    • (2005) Drug Metab Rev , vol.37 , Issue.SUPPL. 2 , pp. 99
    • Kurihara, A.H.1    Kazui, M.2    Ishizuka, T.3    Farid, N.A.4    Ikeda, T.5
  • 19
    • 33645105318 scopus 로고    scopus 로고
    • Interactions of two major metabolites of prasugrel, a thienopyridine antiplatelet agent, with the cytochromes P450
    • Rehmel JL, Eckstein JA, Farid NA, et al. Interactions of two major metabolites of prasugrel, a thienopyridine antiplatelet agent, with the cytochromes P450. Drug Metab Dispos. 2006;34(4):600-607.
    • (2006) Drug Metab Dispos , vol.34 , Issue.4 , pp. 600-607
    • Rehmel, J.L.1    Eckstein, J.A.2    Farid, N.A.3
  • 20
    • 33845451677 scopus 로고    scopus 로고
    • Brandt JT, Payne CD, Wiviott SD, et al. A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation. Am Heart J. 2007;153(1):66.e9-e16.
    • Brandt JT, Payne CD, Wiviott SD, et al. A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation. Am Heart J. 2007;153(1):66.e9-e16.
  • 21
    • 34247256797 scopus 로고    scopus 로고
    • Cytochrome P450 3 A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently
    • Farid NA, Payne CD, Small DS, et al. Cytochrome P450 3 A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently. Clin Pharmacol Ther. 2007;81(5):735-741.
    • (2007) Clin Pharmacol Ther , vol.81 , Issue.5 , pp. 735-741
    • Farid, N.A.1    Payne, C.D.2    Small, D.S.3
  • 22
    • 34249053105 scopus 로고    scopus 로고
    • The disposition of prasugrel, a novel thienopyridine, in humans
    • Farid NA, Smith RL, Gillespie TA, et al. The disposition of prasugrel, a novel thienopyridine, in humans. Drug Metab Dispos. 2007;35(7):1096-1104.
    • (2007) Drug Metab Dispos , vol.35 , Issue.7 , pp. 1096-1104
    • Farid, N.A.1    Smith, R.L.2    Gillespie, T.A.3
  • 23
    • 38349065084 scopus 로고    scopus 로고
    • Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: The randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) study
    • Gilard M, Arnaud B, Cornily JC, et al. Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) study. J Am Coll Cardiol. 2008;51(3):256-260.
    • (2008) J Am Coll Cardiol , vol.51 , Issue.3 , pp. 256-260
    • Gilard, M.1    Arnaud, B.2    Cornily, J.C.3
  • 24
    • 1642453779 scopus 로고    scopus 로고
    • Lau WC, Gurbel PA, Watkins PB, et al. Contribution of hepatic cytochrome P450 3 A4 metabolic activity to the phenomenon of clopidogrel resistance. Circulation. 2004;109(2):166-171.
    • Lau WC, Gurbel PA, Watkins PB, et al. Contribution of hepatic cytochrome P450 3 A4 metabolic activity to the phenomenon of clopidogrel resistance. Circulation. 2004;109(2):166-171.
  • 25
    • 38349032257 scopus 로고    scopus 로고
    • Saint Johns wort enhances clopidogrel responsiveness in clopidogrel resistant volunteers and patients by induction of CYP3A4 isoenzyme (abstr)
    • Lau W, Gurbel P, Carville D, et al. Saint Johns wort enhances clopidogrel responsiveness in clopidogrel resistant volunteers and patients by induction of CYP3A4 isoenzyme (abstr). J Am Coll Cardiol. 2007;49(Suppl A):343A.
    • (2007) J Am Coll Cardiol , vol.49 , Issue.SUPPL. A
    • Lau, W.1    Gurbel, P.2    Carville, D.3
  • 26
    • 67650844202 scopus 로고    scopus 로고
    • Effect of rifampin on the pharmacokinetics and pharmacodynamics of prasugrel in healthy male subjects
    • Farid NA, Jakubowski J, Payne CD, et al. Effect of rifampin on the pharmacokinetics and pharmacodynamics of prasugrel in healthy male subjects. Curr Med Res Opin. 2009;25(8):1821-1829.
    • (2009) Curr Med Res Opin , vol.25 , Issue.8 , pp. 1821-1829
    • Farid, N.A.1    Jakubowski, J.2    Payne, C.D.3
  • 27
    • 58749090547 scopus 로고    scopus 로고
    • Genetic determinants of response to clopidogrel and cardiovascular events
    • Simon T, Verstuyft C, Mary-Krause M, et al. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med. 2009;360(4):363-375.
    • (2009) N Engl J Med , vol.360 , Issue.4 , pp. 363-375
    • Simon, T.1    Verstuyft, C.2    Mary-Krause, M.3
  • 28
    • 58749094444 scopus 로고    scopus 로고
    • Cytochrome p-450 polymorphisms and response to clopidogrel
    • Mega JL, Close SL, Wiviott SD, et al. Cytochrome p-450 polymorphisms and response to clopidogrel. N Engl J Med. 2009;360(4):354-362.
    • (2009) N Engl J Med , vol.360 , Issue.4 , pp. 354-362
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 29
    • 66349133650 scopus 로고    scopus 로고
    • Cytochrome P450 genetic polymorphisms and the response to prasugrel: Relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes
    • Mega JL, Close SL, Wiviott SD, et al. Cytochrome P450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes. Circulation. 2009;119(19):2553- 2560.
    • (2009) Circulation , vol.119 , Issue.19 , pp. 2553-2560
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 30
    • 67649645191 scopus 로고    scopus 로고
    • Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease
    • Varenhorst C, James S, Erlinge D, et al. Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease. Eur Heart J. 2009;30(14):1744-1752.
    • (2009) Eur Heart J , vol.30 , Issue.14 , pp. 1744-1752
    • Varenhorst, C.1    James, S.2    Erlinge, D.3
  • 31
    • 36348943475 scopus 로고    scopus 로고
    • Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel
    • Brandt JT, Close SL, Iturria SJ, et al. Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel. J Thromb Haemost. 2007;5(12):2429-2436.
    • (2007) J Thromb Haemost , vol.5 , Issue.12 , pp. 2429-2436
    • Brandt, J.T.1    Close, S.L.2    Iturria, S.J.3
  • 32
    • 35048856897 scopus 로고    scopus 로고
    • ADP-induced platelet aggregation and platelet reactivity index VASP are good predictive markers for clinical outcomes in non-ST elevation acute coronary syndrome
    • Frere C, Cuisset T, Quilici J, et al. ADP-induced platelet aggregation and platelet reactivity index VASP are good predictive markers for clinical outcomes in non-ST elevation acute coronary syndrome. Thromb Haemost. 2007;98(4):838-843.
    • (2007) Thromb Haemost , vol.98 , Issue.4 , pp. 838-843
    • Frere, C.1    Cuisset, T.2    Quilici, J.3
  • 33
    • 33749503499 scopus 로고    scopus 로고
    • Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation
    • Geisler T, Langer H, Wydymus M, et al. Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation. Eur Heart J. 2006;27(20):2420-2425.
    • (2006) Eur Heart J , vol.27 , Issue.20 , pp. 2420-2425
    • Geisler, T.1    Langer, H.2    Wydymus, M.3
  • 34
    • 33750479499 scopus 로고    scopus 로고
    • Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement
    • Hochholzer W, Trenk D, Bestehorn HP, et al. Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement. J Am Coll Cardiol. 2006;48(9):1742-1750.
    • (2006) J Am Coll Cardiol , vol.48 , Issue.9 , pp. 1742-1750
    • Hochholzer, W.1    Trenk, D.2    Bestehorn, H.P.3
  • 35
    • 34250020766 scopus 로고    scopus 로고
    • Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis
    • Buonamici P, Marcucci R, Migliorini A, et al. Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis. J Am Coll Cardiol. 2007;49(24):2312-2317.
    • (2007) J Am Coll Cardiol , vol.49 , Issue.24 , pp. 2312-2317
    • Buonamici, P.1    Marcucci, R.2    Migliorini, A.3
  • 36
    • 33845474736 scopus 로고    scopus 로고
    • 12(R) rapid analyzer: The VERIfy Thrombosis risk ASsessment (VERITAS) study
    • 12(R) rapid analyzer: the VERIfy Thrombosis risk ASsessment (VERITAS) study. Thromb Res. 2007;119(3):277-284.
    • (2007) Thromb Res , vol.119 , Issue.3 , pp. 277-284
    • Malinin, A.1    Pokov, A.2    Spergling, M.3
  • 37
    • 33750083316 scopus 로고    scopus 로고
    • 12 assay and light transmittance aggregometry for monitoring the individual platelet response to clopidogrel in patients undergoing elective percutaneous coronary intervention
    • 12 assay and light transmittance aggregometry for monitoring the individual platelet response to clopidogrel in patients undergoing elective percutaneous coronary intervention. J Thromb Haemost. 2006;4(11):2516-2518.
    • (2006) J Thromb Haemost , vol.4 , Issue.11 , pp. 2516-2518
    • van Werkum, J.W.1    van der Stelt, C.A.2    Seesing, T.H.3    Hackeng, C.M.4    ten Berg, J.M.5
  • 38
    • 33646441600 scopus 로고    scopus 로고
    • Correlation of a new point-of-care test with conventional optical aggregometry for the assessment of clopidogrel responsiveness
    • von Beckerath N, Pogatsa-Murray G, Wieczorek A, Sibbing D, Schomig A, Kastrati A. Correlation of a new point-of-care test with conventional optical aggregometry for the assessment of clopidogrel responsiveness. Thromb Haemost. 2006;95(5):910-911.
    • (2006) Thromb Haemost , vol.95 , Issue.5 , pp. 910-911
    • von Beckerath, N.1    Pogatsa-Murray, G.2    Wieczorek, A.3    Sibbing, D.4    Schomig, A.5    Kastrati, A.6
  • 39
    • 15944383861 scopus 로고    scopus 로고
    • Flow cytometric analysis of intraplatelet VASP phosphorylation for the detection of clopidogrel resistance in patients with ischemic cardiovascular diseases
    • Aleil B, Ravanat C, Cazenave JP, Rochoux G, Heitz A, Gachet C. Flow cytometric analysis of intraplatelet VASP phosphorylation for the detection of clopidogrel resistance in patients with ischemic cardiovascular diseases. J Thromb Haemost. 2005;3(1):85-92.
    • (2005) J Thromb Haemost , vol.3 , Issue.1 , pp. 85-92
    • Aleil, B.1    Ravanat, C.2    Cazenave, J.P.3    Rochoux, G.4    Heitz, A.5    Gachet, C.6
  • 40
    • 60749105720 scopus 로고    scopus 로고
    • 12 in patients treated with prasugrel or clopidogrel coadministered with aspirin. Am Heart J. 2009;157(3):562.e1-e9.
    • 12 in patients treated with prasugrel or clopidogrel coadministered with aspirin. Am Heart J. 2009;157(3):562.e1-e9.
  • 41
    • 38949094987 scopus 로고    scopus 로고
    • 12 inhibition levels following prasugrel and clopidogrel administration
    • 12 inhibition levels following prasugrel and clopidogrel administration. Thromb Haemost. 2008;99(2):409-415.
    • (2008) Thromb Haemost , vol.99 , Issue.2 , pp. 409-415
    • Jakubowski, J.A.1    Payne, C.D.2    Li, Y.G.3
  • 42
    • 19644366172 scopus 로고    scopus 로고
    • Monitoring of clopidogrel action: Comparison of methods
    • Geiger J, Teichmann L, Grossmann R, et al. Monitoring of clopidogrel action: comparison of methods. Clin Chem. 2005;51(6):957-965.
    • (2005) Clin Chem , vol.51 , Issue.6 , pp. 957-965
    • Geiger, J.1    Teichmann, L.2    Grossmann, R.3
  • 43
    • 0038354521 scopus 로고    scopus 로고
    • Resistance to thienopyridines: Clinical detection of coronary stent thrombosis by monitoring of vasodilator-stimulated phosphoprotein phosphorylation
    • Barragan P, Bouvier JL, Roquebert PO, et al. Resistance to thienopyridines: clinical detection of coronary stent thrombosis by monitoring of vasodilator-stimulated phosphoprotein phosphorylation. Catheter Cardiovasc Interv. 2003;59(3):295-302.
    • (2003) Catheter Cardiovasc Interv , vol.59 , Issue.3 , pp. 295-302
    • Barragan, P.1    Bouvier, J.L.2    Roquebert, P.O.3
  • 44
    • 34447636769 scopus 로고    scopus 로고
    • Vasodilator-stimulated phosphoprotein phosphorylation analysis prior to percutaneous coronary intervention for exclusion of postprocedural major adverse cardiovascular events
    • Bonello L, Paganelli F, Arpin-Bornet M, et al. Vasodilator-stimulated phosphoprotein phosphorylation analysis prior to percutaneous coronary intervention for exclusion of postprocedural major adverse cardiovascular events. J Thromb Haemost. 2007;5(8):1630-1636.
    • (2007) J Thromb Haemost , vol.5 , Issue.8 , pp. 1630-1636
    • Bonello, L.1    Paganelli, F.2    Arpin-Bornet, M.3
  • 45
    • 36949000480 scopus 로고    scopus 로고
    • The significance of vasodilator-stimulated phosphoprotein for risk stratification of stent thrombosis
    • Blindt R, Stellbrink K, de Taeye A, et al. The significance of vasodilator-stimulated phosphoprotein for risk stratification of stent thrombosis. Thromb Haemost. 2007;98(6):1329-1334.
    • (2007) Thromb Haemost , vol.98 , Issue.6 , pp. 1329-1334
    • Blindt, R.1    Stellbrink, K.2    de Taeye, A.3
  • 46
    • 0038649988 scopus 로고    scopus 로고
    • Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity
    • Gurbel PA, Bliden KP, Hiatt BL, O'Connor CM. Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity. Circulation. 2003;107(23):2908-2913.
    • (2003) Circulation , vol.107 , Issue.23 , pp. 2908-2913
    • Gurbel, P.A.1    Bliden, K.P.2    Hiatt, B.L.3    O'Connor, C.M.4
  • 47
    • 8344221349 scopus 로고    scopus 로고
    • Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction
    • Matetzky S, Shenkman B, Guetta V, et al. Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction. Circulation. 2004;109(25):3171-3175.
    • (2004) Circulation , vol.109 , Issue.25 , pp. 3171-3175
    • Matetzky, S.1    Shenkman, B.2    Guetta, V.3
  • 48
    • 34447576539 scopus 로고    scopus 로고
    • Clopidogrel nonresponsiveness in patients undergoing percutaneous coronary intervention with stenting: A systematic review and meta-analysis
    • Snoep JD, Hovens MM, Eikenboom JC, van der Bom JG, Jukema JW, Huisman MV. Clopidogrel nonresponsiveness in patients undergoing percutaneous coronary intervention with stenting: a systematic review and meta-analysis. Am Heart J. 2007;154(2):221-231.
    • (2007) Am Heart J , vol.154 , Issue.2 , pp. 221-231
    • Snoep, J.D.1    Hovens, M.M.2    Eikenboom, J.C.3    van der Bom, J.G.4    Jukema, J.W.5    Huisman, M.V.6
  • 49
    • 33747874088 scopus 로고    scopus 로고
    • A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: The ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial
    • Montalescot G, Sideris G, Meuleman C, et al. A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: the ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial. J Am Coll Cardiol. 2006;48(5):931-938.
    • (2006) J Am Coll Cardiol , vol.48 , Issue.5 , pp. 931-938
    • Montalescot, G.1    Sideris, G.2    Meuleman, C.3
  • 50
    • 27744516843 scopus 로고    scopus 로고
    • Absorption, metabolization, and antiplatelet effects of 300-, 600-, and 900-mg loading doses of clopidogrel: Results of the ISAR-CHOICE (Intracoronary Stenting and Antithrombotic Regimen: Choose Between 3 High Oral Doses for Immediate Clopidogrel Effect) Trial
    • von Beckerath N, Taubert D, Pogatsa-Murray G, Schömig E, Kastrati A, Schömig A. Absorption, metabolization, and antiplatelet effects of 300-, 600-, and 900-mg loading doses of clopidogrel: results of the ISAR-CHOICE (Intracoronary Stenting and Antithrombotic Regimen: Choose Between 3 High Oral Doses for Immediate Clopidogrel Effect) Trial. Circulation. 2005;112(19):2946-2950.
    • (2005) Circulation , vol.112 , Issue.19 , pp. 2946-2950
    • von Beckerath, N.1    Taubert, D.2    Pogatsa-Murray, G.3    Schömig, E.4    Kastrati, A.5    Schömig, A.6
  • 51
    • 58649095289 scopus 로고    scopus 로고
    • Impact of high loading and maintenance dose of clopidogrel within the first 15 days after percutaneous coronary intervention on patient outcome
    • Lemesle G, Delhaye C, Sudre A, et al. Impact of high loading and maintenance dose of clopidogrel within the first 15 days after percutaneous coronary intervention on patient outcome. Am Heart J. 2009;157(2):375-382.
    • (2009) Am Heart J , vol.157 , Issue.2 , pp. 375-382
    • Lemesle, G.1    Delhaye, C.2    Sudre, A.3
  • 52
    • 40649120730 scopus 로고    scopus 로고
    • Clopidogrel 600-mg double loading dose achieves stronger platelet inhibition than conventional regimens: Results from the PREPAIR randomized study
    • L'Allier PL, Ducrocq G, Pranno N, et al. Clopidogrel 600-mg double loading dose achieves stronger platelet inhibition than conventional regimens: results from the PREPAIR randomized study. J Am Coll Cardiol. 2008;51(11):1066-1172.
    • (2008) J Am Coll Cardiol , vol.51 , Issue.11 , pp. 1066-1172
    • L'Allier, P.L.1    Ducrocq, G.2    Pranno, N.3
  • 53
    • 33748948717 scopus 로고    scopus 로고
    • Benefit of a 600-mg loading dose of clopidogrel on platelet reactivity and clinical outcomes in patients with non-ST-segment elevation acute coronary syndrome undergoing coronary stenting
    • Cuisset T, Frere C, Quilici J, et al. Benefit of a 600-mg loading dose of clopidogrel on platelet reactivity and clinical outcomes in patients with non-ST-segment elevation acute coronary syndrome undergoing coronary stenting. J Am Coll Cardiol. 2006;48(7):1339-1345.
    • (2006) J Am Coll Cardiol , vol.48 , Issue.7 , pp. 1339-1345
    • Cuisset, T.1    Frere, C.2    Quilici, J.3
  • 54
    • 7544239072 scopus 로고    scopus 로고
    • High clopidogrel loading dose during coronary stenting: Effects on drug response and interindividual variability
    • Angiolillo D, Fernández-Ortiz A, Bernardo E, et al. High clopidogrel loading dose during coronary stenting: effects on drug response and interindividual variability. Eur Heart J. 2004;25(21):1903-1910.
    • (2004) Eur Heart J , vol.25 , Issue.21 , pp. 1903-1910
    • Angiolillo, D.1    Fernández-Ortiz, A.2    Bernardo, E.3
  • 55
    • 38349137324 scopus 로고    scopus 로고
    • Functional impact of high clopidogrel maintenance dosing in patients undergoing elective percutaneous coronary interventions. Results of a randomized study
    • Angiolillo DJ, Bernardo E, Palazuelos J, et al. Functional impact of high clopidogrel maintenance dosing in patients undergoing elective percutaneous coronary interventions. Results of a randomized study. Thromb Haemost. 2008;99(1):161-168.
    • (2008) Thromb Haemost , vol.99 , Issue.1 , pp. 161-168
    • Angiolillo, D.J.1    Bernardo, E.2    Palazuelos, J.3
  • 56
    • 38349121677 scopus 로고    scopus 로고
    • Functional effects of high clopidogrel maintenance dosing in patients with inadequate platelet inhibition on standard dose treatment
    • Angiolillo DJ, Costa MA, Shoemaker SB, et al. Functional effects of high clopidogrel maintenance dosing in patients with inadequate platelet inhibition on standard dose treatment. Am J Cardiol. 2008;101(4):440-445.
    • (2008) Am J Cardiol , vol.101 , Issue.4 , pp. 440-445
    • Angiolillo, D.J.1    Costa, M.A.2    Shoemaker, S.B.3
  • 57
    • 33745172121 scopus 로고    scopus 로고
    • Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y12 inhibitor: A single ascending dose study in healthy humans
    • Asai F, Jakubowski JA, Naganuma H, et al. Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y12 inhibitor: a single ascending dose study in healthy humans. Platelets. 2006;17(4):209-217.
    • (2006) Platelets , vol.17 , Issue.4 , pp. 209-217
    • Asai, F.1    Jakubowski, J.A.2    Naganuma, H.3
  • 58
    • 33745699564 scopus 로고    scopus 로고
    • The platelet inhibitory effects and pharmacokinetics of prasugrel after administration of loading and maintenance doses in healthy subjects
    • Jakubowski JA, Payne CD, Brandt JT, et al. The platelet inhibitory effects and pharmacokinetics of prasugrel after administration of loading and maintenance doses in healthy subjects. J Cardiovasc Pharmacol. 2006;47(3):377-384.
    • (2006) J Cardiovasc Pharmacol , vol.47 , Issue.3 , pp. 377-384
    • Jakubowski, J.A.1    Payne, C.D.2    Brandt, J.T.3
  • 59
    • 33745152319 scopus 로고    scopus 로고
    • Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y12 inhibitor: A multiple-dose study in healthy humans
    • Matsushima N, Jakubowski JA, Asai F, et al. Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y12 inhibitor: a multiple-dose study in healthy humans. Platelets. 2006;17(4):218-226.
    • (2006) Platelets , vol.17 , Issue.4 , pp. 218-226
    • Matsushima, N.1    Jakubowski, J.A.2    Asai, F.3
  • 60
    • 34447271701 scopus 로고    scopus 로고
    • Comparison of speed of onset of platelet inhibition after loading doses of clopidogrel versus prasugrel in healthy volunteers and correlation with responder status
    • Weerakkody GJ, Jakubowski JA, Brandt JT, et al. Comparison of speed of onset of platelet inhibition after loading doses of clopidogrel versus prasugrel in healthy volunteers and correlation with responder status. Am J Cardiol. 2007;100(2):331-336.
    • (2007) Am J Cardiol , vol.100 , Issue.2 , pp. 331-336
    • Weerakkody, G.J.1    Jakubowski, J.A.2    Brandt, J.T.3
  • 61
    • 34548151179 scopus 로고    scopus 로고
    • Greater inhibition of platelet aggregation and reduced response variability with prasugrel versus clopidogrel: An integrated analysis
    • Weerakkody GJ, Jakubowski JA, Brandt JT, Payne CD, Naganuma H, Winters KJ. Greater inhibition of platelet aggregation and reduced response variability with prasugrel versus clopidogrel: an integrated analysis. J Cardiovasr Pharmacol Ther. 2007;12(3):205-212.
    • (2007) J Cardiovasr Pharmacol Ther , vol.12 , Issue.3 , pp. 205-212
    • Weerakkody, G.J.1    Jakubowski, J.A.2    Brandt, J.T.3    Payne, C.D.4    Naganuma, H.5    Winters, K.J.6
  • 62
    • 36849074168 scopus 로고    scopus 로고
    • Prasugrel: A novel thienopyridine antiplatelet agent. A review of preclinical and clinical studies and the mechanistic basis for its distinct antiplatelet profile
    • Jakubowski JA, Winters KJ, Naganuma H, Wallentin L. Prasugrel: a novel thienopyridine antiplatelet agent. A review of preclinical and clinical studies and the mechanistic basis for its distinct antiplatelet profile. Cardiovasc Drug Rev. 2007;25(4):357-374.
    • (2007) Cardiovasc Drug Rev , vol.25 , Issue.4 , pp. 357-374
    • Jakubowski, J.A.1    Winters, K.J.2    Naganuma, H.3    Wallentin, L.4
  • 63
    • 33646732608 scopus 로고    scopus 로고
    • Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease
    • Jernberg T, Payne CD, Winters KJ, et al. Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease. Eur Heart J. 2006;27(10):1166-1173.
    • (2006) Eur Heart J , vol.27 , Issue.10 , pp. 1166-1173
    • Jernberg, T.1    Payne, C.D.2    Winters, K.J.3
  • 64
    • 37349111065 scopus 로고    scopus 로고
    • Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: The Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial
    • Wiviott SD, Trenk D, Frelinger AL, et al. Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial. Circulation. 2007;116(25):2923-2932.
    • (2007) Circulation , vol.116 , Issue.25 , pp. 2923-2932
    • Wiviott, S.D.1    Trenk, D.2    Frelinger, A.L.3
  • 65
    • 36348977461 scopus 로고    scopus 로고
    • Increased active metabolite formation explains the greater platelet inhibition with prasugrel compared to high-dose clopidogrel
    • Payne CD, Li YG, Small DS, et al. Increased active metabolite formation explains the greater platelet inhibition with prasugrel compared to high-dose clopidogrel. J Cardiovasc Pharmacol. 2007;50(5):555-562.
    • (2007) J Cardiovasc Pharmacol , vol.50 , Issue.5 , pp. 555-562
    • Payne, C.D.1    Li, Y.G.2    Small, D.S.3
  • 66
    • 37849002889 scopus 로고    scopus 로고
    • 12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease
    • 12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease. Eur Heart J. 2008;29(1):21-30.
    • (2008) Eur Heart J , vol.29 , Issue.1 , pp. 21-30
    • Wallentin, L.1    Varenhorst, C.2    James, S.3
  • 67
    • 38949144302 scopus 로고    scopus 로고
    • Switching directly to prasugrel from clopidogrel results in greater inhibition of platelet aggregation in aspirin-treated subjects
    • Payne CD, Li YG, Brandt JT, et al. Switching directly to prasugrel from clopidogrel results in greater inhibition of platelet aggregation in aspirin-treated subjects. Platelets. 2008;19(4):275-281.
    • (2008) Platelets , vol.19 , Issue.4 , pp. 275-281
    • Payne, C.D.1    Li, Y.G.2    Brandt, J.T.3
  • 68
    • 34250714831 scopus 로고    scopus 로고
    • The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite
    • Sugidachi A, Ogawa T, Kurihara A, et al. The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite. J Thromb Haemost. 2007;5(7):1545-1551.
    • (2007) J Thromb Haemost , vol.5 , Issue.7 , pp. 1545-1551
    • Sugidachi, A.1    Ogawa, T.2    Kurihara, A.3
  • 69
    • 56849130022 scopus 로고    scopus 로고
    • Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo
    • Erlinge D, Varenhorst C, Braun OO, et al. Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo. J Am Coll Cardiol. 2008;52(24):1968-1977.
    • (2008) J Am Coll Cardiol , vol.52 , Issue.24 , pp. 1968-1977
    • Erlinge, D.1    Varenhorst, C.2    Braun, O.O.3
  • 70
    • 21644448736 scopus 로고    scopus 로고
    • 12 antagonist, with clopidogrel in percutaneous coronary intervention: Results of the Joint Utilization of Medications to Block Platelets Optimally (JUMBO)-TIMI 26 trial
    • 12 antagonist, with clopidogrel in percutaneous coronary intervention: results of the Joint Utilization of Medications to Block Platelets Optimally (JUMBO)-TIMI 26 trial. Circulation. 2005;111(25):3366-3373.
    • (2005) Circulation , vol.111 , Issue.25 , pp. 3366-3373
    • Wiviott, S.D.1    Antman, E.M.2    Winters, K.J.3
  • 71
    • 36148983750 scopus 로고    scopus 로고
    • Prasugrel versus clopidogrel in patients with acute coronary syndromes
    • Wiviott SD, Braunwald E, McCabe CH, et al. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med. 2007;357(20):2001-2015.
    • (2007) N Engl J Med , vol.357 , Issue.20 , pp. 2001-2015
    • Wiviott, S.D.1    Braunwald, E.2    McCabe, C.H.3
  • 72
    • 43749117048 scopus 로고    scopus 로고
    • Early and late benefits of prasugrel in patients with acute coronary syndromes undergoing percutaneous coronary intervention: A TRITON-TIMI 38 (TRial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet InhibitioN with Prasugrel- Thrombolysis In Myocardial Infarction) analysis
    • Antman EM, Wiviott SD, Murphy SA, et al. Early and late benefits of prasugrel in patients with acute coronary syndromes undergoing percutaneous coronary intervention: a TRITON-TIMI 38 (TRial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet InhibitioN with Prasugrel- Thrombolysis In Myocardial Infarction) analysis. J Am Coll Cardiol. 2008;51(21):2028-2033.
    • (2008) J Am Coll Cardiol , vol.51 , Issue.21 , pp. 2028-2033
    • Antman, E.M.1    Wiviott, S.D.2    Murphy, S.A.3
  • 73
    • 60649112469 scopus 로고    scopus 로고
    • Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): Double-blind, randomised controlled trial
    • Montalescot G, Wiviott SD, Braunwald E, et al. Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): double-blind, randomised controlled trial. Lancet. 2009;373(9665):723-731.
    • (2009) Lancet , vol.373 , Issue.9665 , pp. 723-731
    • Montalescot, G.1    Wiviott, S.D.2    Braunwald, E.3
  • 74
    • 66449131840 scopus 로고    scopus 로고
    • The FDA Prasugrel Review: Adjudication of Myocardial Infarction Controversy
    • Serebruany VL. The FDA Prasugrel Review: Adjudication of Myocardial Infarction Controversy. Cardiology. 2009;114(2):126-129.
    • (2009) Cardiology , vol.114 , Issue.2 , pp. 126-129
    • Serebruany, V.L.1
  • 75
    • 68249144596 scopus 로고    scopus 로고
    • The efficacy and safety of prasugrel with and without a glycoprotein IIb/IIIa inhibitor in patients with acute coronary syndromes undergoing percutaneous intervention: A TRITON-TIMI 38 (Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel-Thrombolysis In Myocardial Infarction 38) Analysis
    • O'Donoghue M, Antman EM, Braunwald E, et al. The efficacy and safety of prasugrel with and without a glycoprotein IIb/IIIa inhibitor in patients with acute coronary syndromes undergoing percutaneous intervention: a TRITON-TIMI 38 (Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel-Thrombolysis In Myocardial Infarction 38) Analysis. J Am Coll Cardiol. 2009;54(8):678-685.
    • (2009) J Am Coll Cardiol , vol.54 , Issue.8 , pp. 678-685
    • O'Donoghue, M.1    Antman, E.M.2    Braunwald, E.3
  • 76
    • 55949103494 scopus 로고    scopus 로고
    • Greater clinical benefit of more intensive oral antiplatelet therapy with prasugrel in patients with diabetes mellitus in the trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel-Thrombolysis in Myocardial Infarction 38
    • Wiviott SD, Braunwald E, Angiolillo DJ, et al. Greater clinical benefit of more intensive oral antiplatelet therapy with prasugrel in patients with diabetes mellitus in the trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel-Thrombolysis in Myocardial Infarction 38. Circulation. 2008;118(16):1626-1636.
    • (2008) Circulation , vol.118 , Issue.16 , pp. 1626-1636
    • Wiviott, S.D.1    Braunwald, E.2    Angiolillo, D.J.3
  • 77
    • 42149119040 scopus 로고    scopus 로고
    • Intensive oral antiplatelet therapy for reduction of ischaemic events including stent thrombosis in patients with acute coronary syndromes treated with percutaneous coronary intervention and stenting in the TRITON-TIMI 38 trial: A subanalysis of a randomised trial
    • Wiviott SD, Braunwald E, McCabe CH, et al. Intensive oral antiplatelet therapy for reduction of ischaemic events including stent thrombosis in patients with acute coronary syndromes treated with percutaneous coronary intervention and stenting in the TRITON-TIMI 38 trial: a subanalysis of a randomised trial. Lancet. 2008;371(9621): 1353-1363.
    • (2008) Lancet , vol.371 , Issue.9621 , pp. 1353-1363
    • Wiviott, S.D.1    Braunwald, E.2    McCabe, C.H.3
  • 78
    • 54149097794 scopus 로고    scopus 로고
    • Reduction in recurrent cardiovascular events with prasugrel compared with clopidogrel in patients with acute coronary syndromes from the TRITON-TIMI 38 trial
    • Murphy SA, Antman EM, Wiviott SD, et al. Reduction in recurrent cardiovascular events with prasugrel compared with clopidogrel in patients with acute coronary syndromes from the TRITON-TIMI 38 trial. Eur Heart J. 2008;29(20):2473-2479.
    • (2008) Eur Heart J , vol.29 , Issue.20 , pp. 2473-2479
    • Murphy, S.A.1    Antman, E.M.2    Wiviott, S.D.3
  • 79
    • 0035908781 scopus 로고    scopus 로고
    • Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: The PCI-CURE study
    • Mehta SR, Yusuf S, Peters RJ, et al. Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study. Lancet. 2001;358(9281):527-533.
    • (2001) Lancet , vol.358 , Issue.9281 , pp. 527-533
    • Mehta, S.R.1    Yusuf, S.2    Peters, R.J.3
  • 80
    • 0037465436 scopus 로고    scopus 로고
    • Early and late effects of clopidogrel in patients with acute coronary syndromes
    • Yusuf S, Mehta S, Zhao F, et al. Early and late effects of clopidogrel in patients with acute coronary syndromes. Circulation. 2003;107(7):966-972.
    • (2003) Circulation , vol.107 , Issue.7 , pp. 966-972
    • Yusuf, S.1    Mehta, S.2    Zhao, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.