Increasing M2 epitope density enhances systemic and mucosal immune responses to influenza A virus

Biotechnology Letters

Volumn 31, Issue 12, 2009, Pages 1851-1856

  Pei, Shaobo ^a,b   Xiong, Ning ^a,b   Zhang, Yong ^a,b   Chen, Shiyun ^a  

^a WUHAN INSTITUTE OF VIROLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Influenza; M2 protein; Mucosal immunity; Repeating epitopes; Systemic immunity

Indexed keywords

HUMORAL IMMUNE RESPONSE; INFLUENZA A VIRUS; INFLUENZA VIRUS; M2 PROTEIN; MDCK CELLS; MORPHOLOGICAL CHANGES; MUCOSAL IMMUNE RESPONSE; MUCOSAL IMMUNITY; MUCOSAL IMMUNIZATION; RECOMBINANT PROTEIN;

ESCHERICHIA COLI; IMMUNIZATION; IMMUNOLOGY; VIRUSES;

PROTEINS;

ESCHERICHIA COLI; INFLUENZA A VIRUS; INFLUENZAVIRUS A; MUS; ORTHOMYXOVIRIDAE;

EPITOPE; IMMUNOGLOBULIN G; INFLUENZA VACCINE; M2 PROTEIN, INFLUENZA A VIRUS; MATRIX PROTEIN; RECOMBINANT PROTEIN; RECOMBINANT VACCINE; SECRETORY IMMUNOGLOBULIN; SUBUNIT VACCINE; VIRUS ANTIBODY;

ANIMAL; ARTICLE; BLOOD; CELL LINE; DOG; ESCHERICHIA COLI; GENE EXPRESSION; GENETICS; IMMUNOLOGY; INFLUENZA VIRUS A H1N1; MOUSE; MUCOSAL IMMUNITY;

ANIMALS; ANTIBODIES, VIRAL; CELL LINE; DOGS; EPITOPES; ESCHERICHIA COLI; GENE EXPRESSION; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A, SECRETORY; IMMUNOGLOBULIN G; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA VACCINES; MICE; RECOMBINANT PROTEINS; VACCINES, SUBUNIT; VACCINES, SYNTHETIC; VIRAL MATRIX PROTEINS;

EID: 73949132540     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-009-0102-6     Document Type: Article

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