Human-in-mouse modeling of primary head and neck squamous cell carcinoma

Laryngoscope

Volumn 119, Issue 12, 2009, Pages 2315-2323

  Law, Jonathan H ^a   Whigham, Amy S ^a   Wirth, Pamela S ^a   Liu, Dan ^a   Pham, Michelle Q ^a   Vadivelu, Sangeetha ^a   Kirkbride, Kellye C ^a   Brown, Brandee T ^a   Burkey, Brian B ^a   Sinard, Robert J ^a   Netterville, James L ^a   Yarbrough, Wendell G ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT INGRAM CANCER CENTER   (United States)

Author keywords

Cancer; Human in mouse modeling; Larynx; Oral cavity; Oropharynx; Pharynx; Sinus; Xenograft head and neck squamous cell carcinoma

Indexed keywords

KI 67 ANTIGEN; LUCIFERASE;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; CANCER TISSUE; CARCINOGENESIS; CARCINOMA; CELL PROLIFERATION; CELL SURVIVAL; CLINICAL ARTICLE; CULTURE TECHNIQUE; EPITHELIUM TUMOR; EXPERIMENTAL MODEL; HEAD AND NECK CARCINOMA; HEAD AND NECK SURGERY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SQUAMOUS CELL CARCINOMA; TISSUE CULTURE; TUMOR BIOPSY; TUMOR CELL; TUMOR GROWTH; XENOGRAFT; ANIMAL; BIOPSY; CANCER TRANSPLANTATION; COMPARATIVE STUDY; CYTOLOGY; EXPERIMENTAL NEOPLASM; FEMALE; HEAD AND NECK TUMOR; MALE; MIDDLE AGED; NUDE MOUSE; PATHOLOGY; TRACHEA; TRANSPLANTATION; TUMOR CELL CULTURE;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BIOPSY; CARCINOMA, SQUAMOUS CELL; CELL PROLIFERATION; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MICE; MICE, NUDE; MIDDLE AGED; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; RATS; TRACHEA; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 73949112906     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1002/lary.20607     Document Type: Article

References (9)

1. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer J Clin 2008;58:71-96.
2. Davies L, Welch HG. Epidemiology of head and neck cancer in the United States. Otolaryngol Head Neck Surg 2006;135:451-457.
3. Chung CH, Parker JS, Karaca G, et al. Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression. Cancer Cell 2004;5:489-500.
4. Roberts TG, Goulart BH, Squitieri L, et al. Trends in the risks and benefits to patients with cancer participating in phase 1 clinical trials. JAMA 2004;292:2130-2140.
5. Sharpless N, Depinho R. The mighty mouse: genetically engineered mouse models in cancer drug development. Nat Rev Drug Discov 2006;5:741-754.
6. Di Maio M, Gridelli C, Normanno N, Perrone F, Ciardiello F. Trying to compose the puzzle with all the pieces: epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer. J Cell Physiol 2005;205:355-363.
7. Mellinghoff IK, Wang MY, Vivanco I, et al. Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. N Engl J Med 2005;353:2012-2024.
8. Fulcher ML, Gabriel S, Burns KA, Yankaskas JR, Randell SH. Well-differentiated human airway epithelial cell cultures. Methods Mol Med 2005;107:183-206.
9. Shores CG, Yarbrough WG. Three-dimensional xenograft model of dysplastic human laryngeal mucosa. Laryngoscope 1998;108:1358-1362.