The continuing challenge of "indeterminate" acute liver failure in children

Journal of Pediatrics

Volumn 155, Issue 6, 2009, Pages 769-770

  Black, Dennis D ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHILD; HUMAN; LIVER FAILURE; NOTE; REPRODUCIBILITY;

CHILD; HUMANS; LIVER FAILURE, ACUTE; REPRODUCIBILITY OF RESULTS;

EID: 73949112044     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2009.07.060     Document Type: Editorial

References (12)

1. Kalambokis G, Manousou P, Vibhakorn S, Marelli L, Cholongitas E, Senzolo M, et al. Transjugular liver biopsy-indications, adequacy, quality of specimens, and complications-a systematic review. J Hepatol 2007;47:284-94. (Pubitemid 47021258)
2. Kirsch R, Yap J, Roberts EA, Cutz E. Clinicopathologic spectrum of massive and submassive hepatic necrosis in infants and children. Hum Pathol 2009;40:516-26.
3. Squires RH Jr, Shneider BL, Bucuvalas J, Alonso E, Sokol RJ, Narkewicz MR, et al. Acute liver failure in children: The first 348 patients in the pediatric acute liver failure study group. J Pediatr 2006;148:652-8.
4. Narkewicz MR, Olio DD, Karpen SJ, Murray KF, Schwarz K, Yazigi N, et al. Pattern of diagnostic evaluation for the causes of pediatric acute liver failure (PALF): an opportunity for quality improvement. J Pediatr 2009;155:801-6.
5. Murray KF, Hadzic N, Wirth S, Bassett M, Kelly D. Drug-related hepatotoxicity and acute liver failure. J Pediatr Gastroenterol Nutr 2008;47: 395-405.
6. Korman JD, Volenberg I, Balko J, Webster J, Schiodt FV, Squires RH Jr, et al. Screening for Wilson disease in acute liver failure: a comparison of currently available diagnostic tests. Hepatology 2008;48:1167-74.
7. James LP, Capparelli EV, Simpson PM, Letzig L, Roberts D, Hinson JA, et al. Acetaminophen-associated hepatic injury: Evaluation of acetaminophen protein adducts in children and adolescents with acetaminophen overdose. Clin Pharmacol Ther 2008;84:684-90.
8. Bond GR. Acetaminophen protein adducts: A review. Clin Toxicol (Phila) 2009;47:2-7.
9. James LP, Alonso EM, Hynan LS, Hinson JA, Davern TJ, Lee WM, et al. Detection of acetaminophen protein adducts in children with acute liver failure of indeterminate cause. Pediatrics 2006;118:e676-81. (Pubitemid 46089993)
10. Alonso EM. Acute liver failure in children: the role of defects in fatty acid oxidation. Hepatology 2005;41:696-9. (Pubitemid 40462928)
11. Shneider BL, Rinaldo P, Emre S, Bucuvalas J, Squires R, Narkewicz M, et al. Abnormal concentrations of esterified carnitine in bile: a feature of pediatric acute liver failure with poor prognosis. Hepatology 2005; 41:717-21. (Pubitemid 40462932)
12. Bernal W, Ma Y, Smith HM, Portmann B, Wendon J, Vergani D. The significance of autoantibodies and immunoglobulins in acute liver failure: a cohort study. J Hepatol 2007;47:664-70. (Pubitemid 47503423)