Clinicopathologic spectrum of massive and submassive hepatic necrosis in infants and children

Human Pathology

Volumn 40, Issue 4, 2009, Pages 516-526

  Kirsch, Richard ^a   Yap, Jason ^b   Roberts, Eve A ^b   Cutz, Ernest ^a  

^a MOUNT SINAI HOSPITAL   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Children; Failure; Liver; Necrosis; Pathology

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN GLUCURONIDE;

ADENOVIRUS INFECTION; ADOLESCENT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; APLASTIC ANEMIA; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AUTOIMMUNE HEPATITIS; BILIRUBIN BLOOD LEVEL; CELL TRANSFORMATION; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ELECTRON MICROSCOPY; FATTY LIVER; FEMALE; GALLBLADDER EPITHELIUM; GIANT CELL; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HISTOCHEMISTRY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOTENSION; IMMUNOHISTOCHEMISTRY; INFANT; ISCHEMIA; LEUKOCYTE COUNT; LIVER BIOPSY; LIVER FAILURE; LIVER NECROSIS; LYMPHOCYTIC INFILTRATION; MALE; MUSHROOM POISONING; PERCUTANEOUS BIOPSY; RETROSPECTIVE STUDY; SCHOOL CHILD; VIRUS HEPATITIS;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; MALE; MASSIVE HEPATIC NECROSIS; MICROSCOPY, ELECTRON, TRANSMISSION; RETROSPECTIVE STUDIES;

EID: 62049083946     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2008.07.018     Document Type: Article

References (36)

1. Cochran J.B., and Losek J.D. Acute liver failure in children. Pediatr Emerg Care 23 (2007) 129-135
2. Dhawan A., Cheeseman P., and Mieli-Vergani G. Approaches to acute liver failure in children. Pediatr Transplant 8 (2004) 584-588
3. Treem W.R. Fulminant hepatic failure in children. J Pediatr Gastroenterol Nutr 35 Suppl 1 (2002) S33-S38
4. Devictor D., Desplanques L., Debray D., et al. Emergency liver transplantation for fulminant liver failure in infants and children. Hepatology 16 (1992) 1156-1162
5. Psacharopoulos H.T., Mowat A.P., Davies M., Portmann B., Silk D.B., and Williams R. Fulminant hepatic failure in childhood: an analysis of 31 cases. Arch Dis Child 55 (1980) 252-258
6. Rivera-Penera T., Moreno J., Skaff C., McDiarmid S., Vargas J., and Ament M.E. Delayed encephalopathy in fulminant hepatic failure in the pediatric population and the role of liver transplantation. J Pediatr Gastroenterol Nutr 24 (1997) 128-134
7. Bendre S.V., Bavdekar A.R., Bhave S.A., Pandit A.N., Chitambar S.D., and Arankalle V.A. Fulminant hepatic failure: etiology, viral markers and outcome. Indian Pediatr 36 (1999) 1107-1112
8. Ciocca M., Moreira-Silva S.F., Alegria S., et al. Hepatitis A as an etiologic agent of acute liver failure in Latin America. Pediatr Infect Dis J 26 (2007) 711-715
9. Ciocca M.E., Ramonet M.D., Cuarterolo M.L., Lopez S.I., Cernadas C., and Alvarez F. Prognostic factors in pediatric acute liver failure. Arch Dis Child 93 (2008) 48-51
10. Hanna J.N., Warnock T.H., Shepherd R.W., and Selvey L.A. Fulminant hepatitis A in indigenous children in north Queensland. Med J Aust 172 (2000) 19-21
11. Moreira-Silva S.F., Frauches D.O., Almeida A.L., Mendonca H.F., and Pereira F.E. Acute liver failure in children: observations in Vitoria, Espirito Santo State, Brazil. Rev Soc Bras Med Trop 35 (2002) 483-486
12. Poddar U., Thapa B.R., Prasad A., Sharma A.K., and Singh K. Natural history and risk factors in fulminant hepatic failure. Arch Dis Child 87 (2002) 54-56
13. Shah U., Habib Z., and Kleinman R.E. Liver failure attributable to hepatitis A virus infection in a developing country. Pediatrics 105 (2000) 436-438
14. Zacarias J., Brinck P., Cordero J., and Velasco M. Etiologies of fulminant hepatitis in pediatric patients in Santiago, Chile. Pediatr Infect Dis J 6 (1987) 686-687
15. Khuroo M.S., and Kamili S. Aetiology and prognostic factors in acute liver failure in India. J Viral Hepat 10 (2003) 224-231
16. Aydogdu S., Ozgenc F., Yurtsever S., Akman S.A., Tokat Y., and Yagci R.V. Our experience with fulminant hepatic failure in Turkish children: etiology and outcome. J Trop Pediatr 49 (2003) 367-370
17. Lee W.S., McKiernan P., and Kelly D.A. Etiology, outcome and prognostic indicators of childhood fulminant hepatic failure in the United kingdom. J Pediatr Gastroenterol Nutr 40 (2005) 575-581
18. Squires Jr. R.H., Shneider B.L., Bucuvalas J., et al. Acute liver failure in children: the first 348 patients in the pediatric acute liver failure study group. J Pediatr 148 (2006) 652-658
19. Ferrell L.C.P., Wright T., et al. Predictive value of pretransplant liver biopsy in patients with fulminant/subfulminant hepatitis. Mod Pathol 6 (1993) 109A
20. Hanau C., Munoz S.J., and Rubin R. Histopathological heterogeneity in fulminant hepatic failure. Hepatology 21 (1995) 345-351
21. Chan P.C., Chen H.L., Ni Y.H., et al. Outcome predictors of fulminant hepatic failure in children. J Formos Med Assoc 103 (2004) 432-436
22. Ferrell L.D.T.N., and Scheuer P.J. Acute and chronic viral hepatitis. In: Mac Sween R.N.M., Burt A.D., Portmann B.C., Ishak K.G., Scheuer P.J., and Anthony P.P. (Eds). Pathology of the Liver. 4th ed. (2000), Churchill Livingstone, London, United Kingdom
23. Horney J.T., and Galambos J.T. The liver during and after fulminant hepatitis. Gastroenterology 73 (1977) 639-645
24. Phillips M.J., and Poucell S. Modern aspects of the morphology of viral hepatitis. Hum Pathol 12 (1981) 1060-1084
25. Hadzic N., Height S., Ball S., et al. Evolution in the management of acute liver failure-associated aplastic anemia in children: a single centre experience. J Hepatol 48 (2008) 68-73
26. Fimmel C.J., Guo L., Compans R.W., et al. A case of syncytial giant cell hepatitis with features of a paramyxoviral infection. Am J Gastroenterol 93 (1998) 1931-1937
27. Hicks J., Barrish J., and Zhu S.H. Neonatal syncytial giant cell hepatitis with paramyxoviral-like inclusions. Ultrastruct Pathol 25 (2001) 65-71
28. Phillips M.J., Blendis L.M., Poucell S., et al. Syncytial giant-cell hepatitis. Sporadic hepatitis with distinctive pathological features, a severe clinical course, and paramyxoviral features. N Engl J Med 324 (1991) 455-460
29. Ben-Ari Z., Broida E., Monselise Y., et al. Syncytial giant-cell hepatitis due to autoimmune hepatitis type II (LKM1+) presenting as subfulminant hepatitis. Am J Gastroenterol 95 (2000) 799-801
30. Fraquelli M., Colli A., Cocciolo M., and Conte D. Adult syncytial giant cell chronic hepatitis due to herbal remedy. J Hepatol 33 (2000) 505-508
31. Kryczka W., Walewska-Zielecka B., and Dutkiewicz E. Acute seronegative hepatitis C manifesting itself as adult giant cell hepatitis-a case report and review of literature. Med Sci Monit 9 Suppl 3 (2003) 29-31
32. Moreno A., Moreno A., Perez-Elias M.J., et al. Syncytial giant cell hepatitis in human immunodeficiency virus-infected patients with chronic hepatitis C: 2 cases and review of the literature. Hum Pathol 37 (2006) 1344-1349
33. Demetris A.J. Central venulitis in liver allografts: considerations of differential diagnosis. Hepatology 33 (2001) 1329-1330
34. Krasinskas A.M., Ruchelli E.D., Rand E.B., Chittams J.L., and Furth E.E. Central venulitis in pediatric liver allografts. Hepatology 33 (2001) 1141-1147
35. Lory J., and Zimmermann A. Endotheliitis-like changes in chronic hepatitis C. Histol Histopathol 12 (1997) 359-366
36. Donaldson B.W., Gopinath R., Wanless I.R., et al. The role of transjugular liver biopsy in fulminant liver failure: relation to other prognostic indicators. Hepatology 18 (1993) 1370-1376