Relationship between heterochromatic interstitial telomeric sequences and chromosome damage induced by the radiomimetic compound streptonigrin in Chinese hamster ovary cells

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 684, Issue 1-2, 2010, Pages 90-97

  Sánchez, Julieta ^a   Bianchi, Martha S ^a   Bolzán, Alejandro D ^a  

^a Instituto Multidisciplinario de Biologia Celular   (Argentina)

Author keywords

Chromosomal aberrations; Interstitial telomeric sequences; PNA FISH; Q FISH; Streptonigrin

Indexed keywords

PEPTIDE NUCLEIC ACID; RUFOCROMOMYCIN;

ANIMAL CELL; ARTICLE; CENTROMERE; CHO CELL; CHROMATID ABERRATION; CHROMATID EXCHANGE; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME BREAKAGE; CHROMOSOME DAMAGE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DICENTRIC CHROMOSOME; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HETEROCHROMATIN; MITOSIS; MOLECULAR PROBE; NONHUMAN; PRIORITY JOURNAL; TELOMERE;

ANIMALS; BASE SEQUENCE; CHO CELLS; CHROMOSOME ABERRATIONS; CRICETINAE; CRICETULUS; MUTAGENS; STREPTONIGRIN; TELOMERE;

CRICETULUS GRISEUS;

EID: 73949111230     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2009.12.005     Document Type: Article

References (21)

1. Lin K.W., and Yan J. Endings in the middle: current knowledge of interstitial telomeric sequences. Mutat. Res. 658 (2008) 95-110
2. Ruíz-Herrera A., Nergadze S.G., Santagostino M., and Giulotto E. Telomeric repeats far from the ends: mechanisms of origin and role in evolution. Cytogenet. Genome Res. 122 (2008) 219-228
3. Faravelli M., Moralli D., Bertoni L., Attolini C., Chernova O., Raimondi E., and Giulotto E. Two extended arrays of a satellite DNA sequence at the centromere and at the short-arm telomere of Chinese hamster chromosome 5. Cytogenet. Cell Genet. 83 (1998) 281-286
4. Bolzán A.D., and Bianchi M.S. Telomeres, interstitial telomeric repeat sequences, and chromosomal aberrations. Mutat. Res. 612 (2006) 189-214
5. Bertoni L., Attolini C., Tessera L., Mucciolo E., and Giulotto E. Telomeric and nontelomeric (TTAGGG)n sequences in gene amplification and chromosome stability. Genomics 24 (1994) 53-62
6. Balajee A.S., Oh H.J., and Natarajan A.T. Analysis of restriction enzyme-induced chromosome aberrations in the interstitial telomeric repeat sequences of CHO and CHE cells by FISH. Mutat. Res. 307 (1994) 307-313
7. Slijepcevic P., Xiao Y., Dominguez I., and Natarajan A.T. Spontaneous and radiation-induced chromosomal breakage at interstitial telomeric sites. Chromosoma 104 (1996) 596-604
8. Alvarez L., Evans J.W., Wilks R., Lucas J.N., Brown M., and Giacia A.J. Chromosomal radiosensitivity at intrachromosomal telomeric sites. Genes Chromosomes Cancer 8 (1993) 8-14
9. Fernández J.L., Gosálvez J., and Goyanes V. High frequency of mutagen-induced chromatid exchanges at interstitial telomere-like DNA séquense blocks of Chinese hamster cells. Chromosome Res. 3 (1995) 281-284
10. Slijepcevic P., and Bryant P.E. Chromosome healing, telomere capture and mechanisms of radiation-induced chromosome breakage. Int. J. Radiat. Biol. 73 (1998) 1-13
11. Bolzán A.D., Páez G.L., and Bianchi M.S. FISH analysis of telomeric repeat sequences and their involvement in chromosomal aberrations induced by radiomimetic compounds in hamster cells. Mutat. Res. 479 (2001) 187-196
12. Sánchez J., Bianchi M.S., and Bolzán A.D. Effect of bleomycin on interstitial telomeric sequences of immortalized Chinese hamster ovary cells. Mutat. Res. 669 (2009) 139-146
13. Slijepcevic P., Xiao Y., Natarajan A.T., and Bryant P.E. Instability of CHO chromosomes containing interstitial telomeric sequences originating from Chinese hamster chromosome 10. Cytogenet. Cell Genet. 76 (1997) 58-60
14. Slijepcevic P., Natarajan A.T., and Bryant P.E. Telomeres and radiation-induced chromosome breakage. Mutagenesis 13 (1998) 45-49
15. Desmaze C., Pirzio L.M., Blaise R., Mondello C., Giulotto E., Murname J.P., and Sabatier L. Interstitial telomeric repeats are not preferentially involved in radiation-induced chromosome aberrations in human cells. Cytogenet. Genome Res. 104 (2004) 123-130
16. Bolzán A.D., and Bianchi M.S. Genotoxicity of streptonigrin: a review. Mutat. Res. 488 (2001) 25-37
17. Bolzán A.D., and Bianchi M.S. Analysis of streptonigrin-induced incomplete chromosome elements and interstitial fragments in Chinese hamster cells using a telomeric PNA probe. Environ. Mol. Mutagen. 44 (2004) 277-282
18. Perry P.E., and Wolff P. New Giemsa method for differential staining of sister chromatids. Nature 251 (1974) 156-158
19. Poon S.S., and Lansdorp P.M. Measurements of telomere length on individual chromosomes by image cytometry. In: Darzynkiewicz Z., Crissman H.A., and Robinson J.P. (Eds). Methods in Cell Biology: Flow Cytometry. 64th ed. vol. 64 (2001), Academic Press, San Diego, CA 69-96 (Chapter 33)
20. Fisher R.A., and Yates F. Statistical Tables for Biological, Agricultural and Medical Research. 5th ed. (1957), Oliver & Boyd, London p. 61
21. Day P., Limoli C.L., and Morgan W.F. Recombination involving interstitial telomere repeat-like sequences promotes chromosomal instability in Chinese hamster cells. Carcinogenesis 19 (1998) 259-266