Effects of lipophilic components on the compatibility of lipid-based formulations with hard gelatin capsules

Journal of Pharmaceutical Sciences

Volumn 99, Issue 1, 2010, Pages 128-141

  Chen, Feng Jing ^a   Etzler, Frank M ^a   Ubben, Johanna ^a   Birch, Amy ^a   Zhong, Li ^a   Schwabe, Robert ^a   Dudhedia, Mayur S ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

Activity; Capsule fill compatibility; Differential scanning calorimetry (DSC); Elastic modulus; Hard gelatin capsule (HGC); Headspace gas chromatography; Henry's law; Lipid based drug delivery system (LBDDS); Liquid filled capsule; Raoult's law; Tensile force; Texture analysis

Indexed keywords

CREMOPHOR; GELATIN; OCTANOIN; PROPYLENE GLYCOL;

ARTICLE; CAPSULE FILLING; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG STABILITY; GAS CHROMATOGRAPHY; GLASS TRANSITION TEMPERATURE; HYDROGEN BOND; LIPOPHILICITY; PHYSICAL CHEMISTRY; TENSILE STRENGTH;

EID: 73949105869     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21805     Document Type: Article

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