Polymorphisms of cytotoxic T lymphocyte-associated antigen-4 and cytokine genes in Taiwanese patients with ankylosing spondylitis

Tissue Antigens

Volumn 75, Issue 2, 2010, Pages 119-126

  Lee, W Y ^a   Chang, Y H ^b,c   Lo, M K ^d   Chang, C P ^d   Yang, S C ^b   Yang, T P ^b   Ho, K T ^e   Juan, C W ^a,f   Shiau, M Y ^g  

^a Lee's Medical Corporation   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d SHOW CHWAN MEMORIAL HOSPITAL   (Taiwan)

^e NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^f NATIONAL CHI NAN UNIVERSITY   (Taiwan)

^g HUNGKUANG UNIVERSITY   (Taiwan)

Author keywords

Ankylosing spondylitis; Cytotoxic T lymphocyte associated antigen 4; Genetic polymorphisms; Interleukin 10; Interleukin 4; Interleukin 6

Indexed keywords

C REACTIVE PROTEIN; CYTOKINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GENOMIC DNA;

ADULT; ANKYLOSING SPONDYLITIS; ARTICLE; CHINESE; CONTROLLED STUDY; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; IMMUNOGENETICS; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TAIWAN;

ANTIGENS, CD; ASIAN CONTINENTAL ANCESTRY GROUP; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; GENES; GENOTYPE; HUMANS; IMMUNOCONJUGATES; INTERLEUKIN-10; INTERLEUKIN-4; INTERLEUKIN-6; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; SPONDYLITIS, ANKYLOSING; TAIWAN;

EID: 73949102296     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/j.1399-0039.2009.01411.x     Document Type: Article

References (43)

1. Brewerton DA, Hart FD, Nichols A, Caffrey M, James DCO, Sturrock RD. Ankylosing spondylitis and HL-A27. Lancet 1973 : 1 : 904 907.
2. Gonzalez-Roces S, Alvarez MC, Gonzalez S et al. HLA-B27 polymorphism and worldwide susceptibility to ankylosing spondylitis. Tissue Antigens 1997 : 49 : 116 123.
3. Chou CT, Pai L, Chang DM, Lee CF, Liang MH, Schumacher HR. Prevalence of rheumatic disease in Taiwan: a population-based study of urban, suburban, rural difference. J Rheumatol 1994 : 21 : 302 336.
4. Beasley RP, Bennett PH. Low prevalence of rheumatoid arthritis in Chinese. J Rheumatol 1983 : 10 (Suppl) : 11 5.
5. Robinson WP, van der Linden SM, Khan MA, Rentsch HU, Cats A, Russell A. HLA-Bw60 increases susceptibility to ankylosing spondylitis in HLA-B27+ patients. Arthritis Rheum 1989 : 32 : 1135 1141.
6. Hohler T, Schaper T, Schneider PM, Meyer zum Buschenfelde KH, Marker-Hermann E. Association of different tumor necrosis factor alpha promoter allele frequencies with ankylosing spondylitis in HLA-B27 positive individuals. Arthritis Rheum 1998 : 41 : 1489 1492.
7. Brown MA, Pile KD, Kennedy LG et al. HLA class I associations of ankylosing spondylitis in the white population in the United Kingdom. Ann Rheum Dis 1996 : 55 : 268 270.
8. Canete JD, Martinez SE, Farres J et al. Differential Th1/Th2 cytokine patterns in chronic arthritis: interferon gamma is highly expressed in synovium of rheumatoid arthritis compared with seronegative spondyloarthropathies. J Rheumatol 2000 : 59 : 263 268.
9. Rudwaleit M, Siegert S, Yin Z et al. Low T cell production of TNFα and IFNγ in ankylosing spondylitis: its relation to HLA-B27 and influence of the TNF-308 gene polymorphism. Ann Rheum Dis 2001 : 60 : 36 42.
10. Simon AK, Seipelt E, Sieper J. Divergent T-cell cytokine patterns in inflammatory arthritis. Proc Natl Acad Sci USA 1994 : 91 : 8562 8566.
11. Yin Z, Siegert S, Neure L et al. The elevated ratio of interferon gamma- /interleukin-4-positive T cells found in synovial fluid and synovial membrane of rheumatoid arthritis can be changed by interleukin-4 but not by interleukin-10 or transforming growth factor beta. Rheumatology 1999 : 38 : 1058 1067.
12. Canete JD, Martinez SE, Farres J et al. Differential Th1/Th2 cytokine patterns in chronic arthritis: interferon-γ is highly expressed in synovium of rheumatoid arthritis compared with seronegative spondylarthropathies. Ann Rheum Dis 2000 : 59 : 263 268.
13. Westendorp RG, Langermans JA, Huizinga TW et al. Genetic influence on cytokine production and fatal meningococcal disease. Lancet 1997 : 349 : 170 173.
14. Wilson AG, Symons JA, McDowell TL, McDevitt HO, Duff GW. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci USA 1997 : 94 : 3195 3199.
15. Turner DM, Williams DM, Sankaran D, Lazarus M, Sinnott PJ, Hutchinson IV. An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet 1997 : 24 : 1 8.
16. Rosenwasser LJ, Klemm DJ, Dresback JK. Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy. Clin Exp Allergy 1995 : 25 : 74 8.
17. Song Z, Casolaro V, Chen R, Georas SN, Monos D, Ono SJ. Polymorphic nucleotides within the human IL-4 promoter that mediate overexpression of the gene. J Immunol 1996 : 156 : 424 429.
18. Shiau MY, Lo MK, Chang CP, Yang TP, Ho KT, Chang YH. Association of tumor necrosis factor-α promoter polymorphisms with ankylosing spondylitis in Taiwan. Ann Rheum Dis 2007 : 55 : 562 563.
19. Chou CT, Timms AE, Wei JC, Tsai WC, Wordsworth BP, Brown MA. Replication of association of IL1 gene complex members with ankylosing spondylitis in Taiwanese Chinese. Ann Rheum Dis 2006 : 65 : 1106 1109.
20. Yen JH, Tsai WC, Chen CJ et al. Cytochrome P450 1A1 and manganese superoxide dismutase genes polymorphisms in ankylosing spondylitis. Immunol Lett 2003 : 88 : 113 116.
21. Shiau MY, Huang CN, Yang TP et al. Cytokine promoter polymorphisms in Taiwanese patients with Graves' disease. Clin Biochem 2007 : 40 : 231 237.
22. Chang YH, Huang CN, Wu CY, Shiau MY. Association of IL-10 A-592C and T-819C polymorphisms with type 2 diabetes mellitus. Hum Immunol 2005 : 66 : 1258 1263.
23. Chistiakov DA, Turakulov RI. CTLA-4 and its role in autoimmune thyroid disease. J Mol Endocrinol 2003 : 31 : 21 36.
24. Van der Linden S, Valkenburg HA, Cats A. Evaluation of diagnostic criteria for ankylosing spondylitis: a proposal for modification of the New York criteria. Arthritis Rheum 1984 : 27 : 361 368.
25. Bunce M, Fanning GC, Welsh KI. Comprehensive, serologically equivalent DNA typing for HLA-B by PCR amplification with sequence-specific primers. Tissue Antigens 1995 : 45 : 81 90.
26. Wei JCC, Tsai WC, Lin HS, Tsai CY, Chou CT. HLA-B60 and B61 are strongly associated with ankylosing spondylitis in HLA-B27-negative Taiwan Chinese patients. Rheumatology 2004 : 43 : 839 842.
27. Bijlsma FJ, vanKuik J, Tilanus MGJ et al. Donor interleukin-4 promoter gene polymorphism influences allograft rejection after heart transplantation. J Heart Lung Transplant 2002 : 21 : 340 346.
28. Chang YH, Huang CN, Shiau MY. The C-174G promoter polymorphism of the IL-6 gene that affects insulin sensitivity in Caucasians is not involved in the pathogenesis of Taiwanese Type 2 diabetes mellitus. Eur Cytokine Netw 2004 : 15 : 117 119.
29. Ahmed S, Ihara K, Kanemitsu S et al. Association of CTLA-4 but not CD28 gene polymorphisms with systemic lupus erythematosus in the Japanese population. Rheumatology 2001 : 40 : 662 667.
30. Bednarczuk T, Hiromatsu Y, Fukutani T et al. Association of cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) gene polymorphism and non-genetic factors with Graves' ophthalmopathy in European and Japanese populations. Eur J Endocrinol 2003 : 148 : 13 8.
31. Rudwaleit M, Siegert S, Yin Z et al. Low T cell production of TNFalpha and IFNgamma in ankylosing spondylitis: its relation to HLA-B27 and influence of the TNF-308 gene polymorphism. Ann Rheum Dis 2001 : 60 : 36 42.
32. Wellcome Trust Case Control Consortium and The Australo-Anglo-American Spondylitis Consortium. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet 2007 : 39 : 1329 1337.
33. Rahman P, Inman RD, Gladman DD, Reeve JP, Peddle L, Maksymowych WP. Association of interleukin-23 receptor variants with ankylosing spondylitis. Arthritis Rheum 2008 : 58 : 1020 1025.
34. Sims AM, Timms AE, Bruges-Armas J. Prospective meta-analysis of interleukin 1 gene complex polymorphisms confirms associations with ankylosing spondylitis. Ann Rheum Dis 2008 : 67 : 1305 1309.
35. Schwartz JC, Zhang X, Fedorov AA, Natheson SG, Almo SC. Structural basis for co-stimulation by the human CTLA-4/B7-2 complex. Nature 2001 : 410 : 604 608.
36. Thompson CB, Allison JP. The emerging role of CTLA-4 as an immune attenuator. Immunity 1997 : 7 : 445 450.
37. Doyle AM, Mullen AC, Villarino AV et al. Induction of cytotoxic T lymphocyte antigen 4 (CTLA-4) restricts clonal expansion of helper T cells. J Exp Med 2001 : 194 : 893 902.
38. Ueda H, Howson JM, Esposito L et al. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 2003 : 423 : 506 511.
39. Kouki T, Sawai Y, Gardine CA, Fisfalen ME, Alegre ML, DeGroot LJ. CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease. J Immunol 2000 : 165 : 6606 6611.
40. Maurer M, Loserth S, Kolb-Maurer A et al. A polymorphism in the human cytotoxic T-lymphocyte antigen 4 (CTLA4) gene (exon 1 +49) alters T-cell activation. Immunogenetics 2002 : 54 : 1 8.
41. Ligers A, Teleshova N, Masterman T, Huang WX, Hillert J. CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms. Genes Immun 2001 : 2 : 145 152.
42. Wang XB, Zhao X, Giscombe R, Lefvert AK. A CTLA-4 gene polymorphism at position -318 in the promoter region affects the expression of protein. Genes Immun 2002 : 3 : 233 234.
43. Braun J, Donner H, Siegmund T, Walfish PG, Usadel KH, Badenhoop K. CTLA-4 promoter variants in patients with Graves' disease and Hashimoto's thyroiditis. Tissue Antigens 1998 : 51 : 563 566.