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Volumn 35, Issue 6, 2009, Pages 1257-1264

Targeted disruption of S100P suppresses tumor cell growth by down-regulation of cyclin D1 and CDK2 in human hepatocellular carcinoma

Author keywords

Apoptosis; Cell cycle; Cell growth; Hepatocellular carcinoma; S100P

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE 2; PROTEIN S 100; CARRIER PROTEIN; CDK2 PROTEIN, HUMAN; NUCLEAR PROTEIN; S100PBP PROTEIN, HUMAN;

EID: 73949092126     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000442     Document Type: Article
Times cited : (37)

References (37)
  • 1
    • 38849119717 scopus 로고    scopus 로고
    • Molecular pathogenesis of hepatocellular carcinoma
    • Wong CM and Ng IO: Molecular pathogenesis of hepatocellular carcinoma. Liver Int 28: 160-174, 2008.
    • (2008) Liver Int , vol.28 , pp. 160-174
    • Wong, C.M.1    Ng, I.O.2
  • 2
    • 0036096420 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Diagnosis and treatment
    • Befeler AS and Di Bisceglie AM: Hepatocellular carcinoma: diagnosis and treatment. Gastroenterology 122: 1609-1619, 2002.
    • (2002) Gastroenterology , vol.122 , pp. 1609-1619
    • Befeler, A.S.1    Di Bisceglie, A.M.2
  • 3
    • 0034077091 scopus 로고    scopus 로고
    • Surgical resection versus transplantation for early hepatocellular carcinoma: Clues for the best strategy
    • Llovet JM, Bruix J and Gores GJ: Surgical resection versus transplantation for early hepatocellular carcinoma: clues for the best strategy. Hepatology 31: 1019-1021, 2000.
    • (2000) Hepatology , vol.31 , pp. 1019-1021
    • Llovet, J.M.1    Bruix, J.2    Gores, G.J.3
  • 4
    • 0034088858 scopus 로고    scopus 로고
    • AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
    • Satoh S, Daigo Y, Furukawa Y, et al: AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Nat Genet 24: 245-250, 2000.
    • (2000) Nat Genet , vol.24 , pp. 245-250
    • Satoh, S.1    Daigo, Y.2    Furukawa, Y.3
  • 5
    • 0345006147 scopus 로고    scopus 로고
    • Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas
    • De La Coste A, Romagnolo B, Billuart P, et al: Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc Natl Acad Sci USA 95: 8847-8851, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8847-8851
    • De La Coste, A.1    Romagnolo, B.2    Billuart, P.3
  • 6
    • 0141453688 scopus 로고    scopus 로고
    • Clinicopathologic significance of genetic alterations in hepatocellular carcinoma
    • Pang A, Ng IO, Fan ST and Kwong YL: Clinicopathologic significance of genetic alterations in hepatocellular carcinoma. Cancer Genet Cytogenet 146: 8-15, 2003.
    • (2003) Cancer Genet Cytogenet , vol.146 , pp. 8-15
    • Pang, A.1    Ng, I.O.2    Fan, S.T.3    Kwong, Y.L.4
  • 7
    • 0028928357 scopus 로고
    • The S100 protein family: History, function, and expression
    • Zimmer DB, Cornwall EH, Landar A and Song W: The S100 protein family: history, function, and expression. Brain Res Bull 37: 417-429, 1995.
    • (1995) Brain Res Bull , vol.37 , pp. 417-429
    • Zimmer, D.B.1    Cornwall, E.H.2    Landar, A.3    Song, W.4
  • 8
    • 0029669991 scopus 로고    scopus 로고
    • The S100 family of EF-hand calcium-binding proteins: Functions and pathology
    • Schafer BW and Heizmann CW: The S100 family of EF-hand calcium-binding proteins: functions and pathology. Trends Biochem Sci 21: 134-140, 1996.
    • (1996) Trends Biochem Sci , vol.21 , pp. 134-140
    • Schafer, B.W.1    Heizmann, C.W.2
  • 9
    • 0034995073 scopus 로고    scopus 로고
    • S100: A multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles
    • Donato R: S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. Int J Biochem Cell Biol 33: 637-668, 2001.
    • (2001) Int J Biochem Cell Biol , vol.33 , pp. 637-668
    • Donato, R.1
  • 10
    • 0036580943 scopus 로고    scopus 로고
    • S100 proteins: Structure, functions and pathology
    • Heizmann CW, Fritz G and Schafer BW: S100 proteins: structure, functions and pathology. Front Biosci 7: d1356-d1368, 2002.
    • (2002) Front Biosci , vol.7
    • Heizmann, C.W.1    Fritz, G.2    Schafer, B.W.3
  • 11
    • 0026600297 scopus 로고
    • Purification and characterization of a new member of the S-100 protein family from human placenta
    • Emoto Y, Kobayashi R, Akatsuka H and Hidaka H: Purification and characterization of a new member of the S-100 protein family from human placenta. Biochem Biophys Res Commun 182: 1246-1253, 1992.
    • (1992) Biochem Biophys Res Commun , vol.182 , pp. 1246-1253
    • Emoto, Y.1    Kobayashi, R.2    Akatsuka, H.3    Hidaka, H.4
  • 13
    • 85184381304 scopus 로고    scopus 로고
    • Gribenko A, Lopez MM, Richardson JM, 3rd and Makhatadze GI: Cloning, overexpression, purification, and spectroscopic characterization of human S100P. Protein Sci 7: 211-215, 1998.
    • Gribenko A, Lopez MM, Richardson JM, 3rd and Makhatadze GI: Cloning, overexpression, purification, and spectroscopic characterization of human S100P. Protein Sci 7: 211-215, 1998.
  • 14
  • 15
    • 24744467189 scopus 로고    scopus 로고
    • Expression of S100P protein correlates with and contributes to the tumorigenic capacity of HeLa cervical carcinoma cells
    • Gibadulinova A, Barathova M, Kopacek J, et al: Expression of S100P protein correlates with and contributes to the tumorigenic capacity of HeLa cervical carcinoma cells. Oncol Rep 14: 575-582, 2005.
    • (2005) Oncol Rep , vol.14 , pp. 575-582
    • Gibadulinova, A.1    Barathova, M.2    Kopacek, J.3
  • 16
    • 33644876172 scopus 로고    scopus 로고
    • S100P calcium-binding protein expression is associated with high-risk proliferative lesions of the breast
    • Schor AP, Carvalho FM, Kemp C, Silva ID and Russo J: S100P calcium-binding protein expression is associated with high-risk proliferative lesions of the breast. Oncol Rep 15: 3-6, 2006.
    • (2006) Oncol Rep , vol.15 , pp. 3-6
    • Schor, A.P.1    Carvalho, F.M.2    Kemp, C.3    Silva, I.D.4    Russo, J.5
  • 17
    • 14544292891 scopus 로고    scopus 로고
    • Differential gene expression in colon cancer of the caecum versus the sigmoid and rectosigmoid
    • Birkenkamp-Demtroder K, Olesen SH, Sorensen FB, et al: Differential gene expression in colon cancer of the caecum versus the sigmoid and rectosigmoid. Gut 54: 374-384, 2005.
    • (2005) Gut , vol.54 , pp. 374-384
    • Birkenkamp-Demtroder, K.1    Olesen, S.H.2    Sorensen, F.B.3
  • 18
    • 0034131796 scopus 로고    scopus 로고
    • S100P calcium-binding protein overexpression is associated with immortalization of human breast epithelial cells in vitro and early stages of breast cancer development in vivo
    • Guerreiro Da Silva ID, Hu YF, Russo IH, et al: S100P calcium-binding protein overexpression is associated with immortalization of human breast epithelial cells in vitro and early stages of breast cancer development in vivo. Int J Oncol 16: 231-240, 2000.
    • (2000) Int J Oncol , vol.16 , pp. 231-240
    • Guerreiro Da Silva, I.D.1    Hu, Y.F.2    Russo, I.H.3
  • 19
    • 0038179900 scopus 로고    scopus 로고
    • Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer
    • Logsdon CD, Simeone DM, Binkley C, et al: Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer. Cancer Res 63: 2649-2657, 2003.
    • (2003) Cancer Res , vol.63 , pp. 2649-2657
    • Logsdon, C.D.1    Simeone, D.M.2    Binkley, C.3
  • 21
    • 4143116938 scopus 로고    scopus 로고
    • S100 family members and trypsinogens are predictors of distant metastasis and survival in early-stage non-small cell lung cancer
    • Diederichs S, Bulk E, Steffen B, et al: S100 family members and trypsinogens are predictors of distant metastasis and survival in early-stage non-small cell lung cancer. Cancer Res 64: 5564-5569, 2004.
    • (2004) Cancer Res , vol.64 , pp. 5564-5569
    • Diederichs, S.1    Bulk, E.2    Steffen, B.3
  • 22
    • 1542636969 scopus 로고    scopus 로고
    • Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling
    • Sato N, Fukushima N, Matsubayashi H and Goggins M: Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling. Oncogene 23: 1531-1538, 2004.
    • (2004) Oncogene , vol.23 , pp. 1531-1538
    • Sato, N.1    Fukushima, N.2    Matsubayashi, H.3    Goggins, M.4
  • 23
    • 4944239856 scopus 로고    scopus 로고
    • Interleukin-6 is a potent inducer of S100P, which is up-regulated in androgen-refractory and metastatic prostate cancer
    • Hammacher A, Thompson EW and Williams ED: Interleukin-6 is a potent inducer of S100P, which is up-regulated in androgen-refractory and metastatic prostate cancer. Int J Biochem Cell Biol 37: 442-450, 2005.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 442-450
    • Hammacher, A.1    Thompson, E.W.2    Williams, E.D.3
  • 24
    • 0037262656 scopus 로고    scopus 로고
    • Retinoic acid increases expression of the calcium-binding protein S100P in human gastric cancer cells
    • Shyu RY, Huang SL and Jiang SY: Retinoic acid increases expression of the calcium-binding protein S100P in human gastric cancer cells. J Biomed Sci 10: 313-319, 2003.
    • (2003) J Biomed Sci , vol.10 , pp. 313-319
    • Shyu, R.Y.1    Huang, S.L.2    Jiang, S.Y.3
  • 25
    • 0031800720 scopus 로고    scopus 로고
    • Elevated expression of S100P, CAPL and MAGE 3 in doxorubicin-resistant cell lines: Comparison of mRNA differential display reverse transcription-polymerase chain reaction and subtractive suppressive hybridization for the analysis of differential gene expression
    • Bertram J, Palfner K, Hiddemann W and Kneba M: Elevated expression of S100P, CAPL and MAGE 3 in doxorubicin-resistant cell lines: comparison of mRNA differential display reverse transcription-polymerase chain reaction and subtractive suppressive hybridization for the analysis of differential gene expression. Anticancer Drugs 9: 311-317, 1998.
    • (1998) Anticancer Drugs , vol.9 , pp. 311-317
    • Bertram, J.1    Palfner, K.2    Hiddemann, W.3    Kneba, M.4
  • 26
    • 18544365698 scopus 로고    scopus 로고
    • Gene-expression profiles predict survival of patients with lung adenocarcinoma
    • Beer DG, Kardia SL, Huang CC, et al: Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med 8: 816-824, 2002.
    • (2002) Nat Med , vol.8 , pp. 816-824
    • Beer, D.G.1    Kardia, S.L.2    Huang, C.C.3
  • 28
    • 0029119740 scopus 로고
    • Cell cycle control in mammalian cells: Role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs)
    • Grana X and Reddy EP: Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). Oncogene 11: 211-219, 1995.
    • (1995) Oncogene , vol.11 , pp. 211-219
    • Grana, X.1    Reddy, E.P.2
  • 29
    • 24344480020 scopus 로고    scopus 로고
    • Mutation and homozygous deletion analyses of genes that control the G1/S transition of the cell cycle in skin melanoma: P53, p21, p16 and p15
    • Soto Martinez JL, Cabrera Morales CM, Serrano Ortega S and Lopez-Nevot MA: Mutation and homozygous deletion analyses of genes that control the G1/S transition of the cell cycle in skin melanoma: p53, p21, p16 and p15. Clin Transl Oncol 7: 156-164, 2005.
    • (2005) Clin Transl Oncol , vol.7 , pp. 156-164
    • Soto Martinez, J.L.1    Cabrera Morales, C.M.2    Serrano Ortega, S.3    Lopez-Nevot, M.A.4
  • 30
    • 34247630071 scopus 로고    scopus 로고
    • Placental S100 (S100P) and GATA3: Markers for transitional epithelium and urothelial carcinoma discovered by complementary DNA microarray
    • Higgins JP, Kaygusuz G, Wang L, et al: Placental S100 (S100P) and GATA3: markers for transitional epithelium and urothelial carcinoma discovered by complementary DNA microarray. Am J Surg Pathol 31: 673-680, 2007.
    • (2007) Am J Surg Pathol , vol.31 , pp. 673-680
    • Higgins, J.P.1    Kaygusuz, G.2    Wang, L.3
  • 31
    • 33846539778 scopus 로고    scopus 로고
    • Increased SOCS6 stability with PMA requires its N-terminal region and the Erk pathway via Pkcdelta activation
    • Hwang MN, Ha TH, Park J, et al: Increased SOCS6 stability with PMA requires its N-terminal region and the Erk pathway via Pkcdelta activation. Biochem Biophys Res Commun 354: 184-189, 2007.
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 184-189
    • Hwang, M.N.1    Ha, T.H.2    Park, J.3
  • 32
    • 33646504879 scopus 로고    scopus 로고
    • Molecular characterization of adenocarcinoma and squamous carcinoma of the uterine cervix using microarray analysis of gene expression
    • Chao A, Wang TH, Lee YS, et al: Molecular characterization of adenocarcinoma and squamous carcinoma of the uterine cervix using microarray analysis of gene expression. Int J Cancer 119: 91-98, 2006.
    • (2006) Int J Cancer , vol.119 , pp. 91-98
    • Chao, A.1    Wang, T.H.2    Lee, Y.S.3
  • 33
    • 33845451531 scopus 로고    scopus 로고
    • Differential gene expression between flat adenoma and normal mucosa in the colon in a microarray analysis
    • Kita H, Hikichi Y, Hikami K, et al: Differential gene expression between flat adenoma and normal mucosa in the colon in a microarray analysis. J Gastroenterol 41: 1053-1063, 2006.
    • (2006) J Gastroenterol , vol.41 , pp. 1053-1063
    • Kita, H.1    Hikichi, Y.2    Hikami, K.3
  • 34
    • 25844461787 scopus 로고    scopus 로고
    • Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling
    • Nam SW, Park JY, Ramasamy A, et al: Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling. Hepatology 42: 809-818, 2005.
    • (2005) Hepatology , vol.42 , pp. 809-818
    • Nam, S.W.1    Park, J.Y.2    Ramasamy, A.3
  • 35
    • 1242272130 scopus 로고    scopus 로고
    • S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE)
    • Arumugam T, Simeone DM, Schmidt AM and Logsdon CD: S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE). J Biol Chem 279: 5059-5065, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 5059-5065
    • Arumugam, T.1    Simeone, D.M.2    Schmidt, A.M.3    Logsdon, C.D.4
  • 36
    • 31544449414 scopus 로고    scopus 로고
    • Induction of metastasis by S100P in a rat mammary model and its association with poor survival of breast cancer patients
    • Wang G, Platt-Higgins A, Carroll J, et al: Induction of metastasis by S100P in a rat mammary model and its association with poor survival of breast cancer patients. Cancer Res 66: 1199-1207, 2006.
    • (2006) Cancer Res , vol.66 , pp. 1199-1207
    • Wang, G.1    Platt-Higgins, A.2    Carroll, J.3
  • 37
    • 34247876044 scopus 로고    scopus 로고
    • S-phase reduction in T47D human breast cancer epithelial cells induced by an S100P antisense-retroviral construct
    • Beissel B, Silva ID, Pesquero JB, Russo J, Schor N and Bellini MH: S-phase reduction in T47D human breast cancer epithelial cells induced by an S100P antisense-retroviral construct. Oncol Rep 17: 611-615, 2007.
    • (2007) Oncol Rep , vol.17 , pp. 611-615
    • Beissel, B.1    Silva, I.D.2    Pesquero, J.B.3    Russo, J.4    Schor, N.5    Bellini, M.H.6


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