Screening and isolation of a natural dopamine D1 receptor antagonist using cell-based assays

Journal of Biotechnology

Volumn 145, Issue 3, 2010, Pages 304-309

  Yu, Sungryul ^a   Park, Jeong Soo ^b   Paredes, Verenice ^a   Song, Myoung Chong ^a   Baek, Nam In ^a   Lee, Sang Ik ^c   Lim, Jong Soon ^c   Cho, Nam Young ^c   Yoon, Jaeseung ^a   Baek, Kwanghee ^a  

^a Kyung Hee University   (South Korea)

^b PanGen Biotech Inc   (South Korea)

^c Daejeon University   (South Korea)

Author keywords

Cell based assay; D1 receptor; Dopamine; Gleditsia sinensis; Gleditsioside F

Indexed keywords

CELL-BASED; CELL-BASED ASSAYS; DOSE-DEPENDENT; EXPRESSION VECTORS; HIGH AFFINITY; LIGAND BINDING; MEDICINAL PLANTS; RECEPTOR ANTAGONISTS; SPECIFIC BINDING; STABLE CHINESE HAMSTER OVARY CELL LINES;

ASSAYS; CELL CULTURE; FETAL MONITORING; STRUCTURAL ANALYSIS;

BRAIN;

CYCLIC AMP; DOPAMINE; DOPAMINE 1 RECEPTOR; FLUPENTIXOL; GLEDITSIA SINENSIS EXTRACT; GLEDITSIOSIDE F; HERBACEOUS AGENT; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG EFFICACY; DRUG ISOLATION; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG STRUCTURE; GLEDITSIA; GLEDITSIA SINENSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BIOLOGICAL ASSAY; BIOLOGICAL PRODUCTS; CHO CELLS; CRICETINAE; CRICETULUS; DOPAMINE ANTAGONISTS; DRUG EVALUATION, PRECLINICAL; GLEDITSIA; HUMANS; LIGANDS; RECEPTORS, DOPAMINE D1; SAPONINS; SMALL MOLECULE LIBRARIES;

CRICETULUS GRISEUS; GLEDITSIA SINENSIS;

EID: 73749088532     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2009.12.005     Document Type: Article

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