Hepatoprotective and toxicological assessment of an ethnomedicinal plant Euphorbia fusiformis Buch.-Ham.ex D.Don

Journal of Ethnopharmacology

Volumn 127, Issue 2, 2010, Pages 463-467

  Anusuya, N ^a   Raju, K ^a   Manian, S ^a  

^a BHARATHIAR UNIVERSITY   (India)

Author keywords

Acute and subchronic toxicity; Euphorbia fusiformis; Hepatoprotective; Histological and biochemical parameters; Rifampicin

Indexed keywords

EUPHORBIA FUSIFORMIS EXTRACT; LIVER PROTECTIVE AGENT; PLANT EXTRACT; RIFAMPICIN; SILYMARIN; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CHRONIC TOXICITY; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; EUPHORBIA; EUPHORBIA FUSIFORMIS; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HISTOPATHOLOGY; LD 50; LIVER NECROSIS; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; RAT; TOXICITY TESTING;

ANIMALS; DRUG-INDUCED LIVER INJURY; EUPHORBIA; LIVER; MALE; MEDICINE, TRADITIONAL; MICE; PLANT EXTRACTS; PLANT TUBERS; PLANTS, MEDICINAL; RATS; RATS, WISTAR;

EUPHORBIA; EUPHORBIACEAE; MUS; RATTUS;

EID: 73749084680     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.10.012     Document Type: Article

References (37)

1. Acocella G. Clinical pharmacokinetics of rifampicin. Clinical Pharmacokinetics 3 (1978) 108-127
2. Ansari R.A., Tripathi S.C., Patnaik G.K., and Dhawan B.N. Antihepatotoxic properties of picroliv: an active fraction from rhizomes of Picorrhiza kurroa. Journal of Ethnopharmacology 34 (1991) 61-68
3. Bindra R.S., Satti N.K., and Suri O.P. Isolation and structures of ellagic acid derivatives from Euphorbia acaulis. Phytochemistry 27 (1988) 2313-2315
4. Bradford B.U., Kono H., Isayama F., Kosyk O., Wheeler M.D., Akiyama T.E., Bleye L., Krausz K.W., Gonzalez F.J., Koop D.R., and Rusyn I. Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol-induced oxidative DNA damage in rodent liver. Hepatology 41 (2005) 336-344
5. Corns C.M. Herbal remedies and clinical biochemistry. Annals of Clinical Biochemistry 40 (2003) 489-507
6. Dai Y., and Cederbaum A.I. Cytotoxicity of acetaminophen in human cytochrome P4502E1-transfected HepG2 cells. The Journal of Pharmacology and Experimental Therapeutics 273 (1995) 1497-1505
7. Docie J.V. Practical Hematology. 2nd ed. (1958), J&A Churchil Ltd., London
8. Folin O., and Wu H. A system of blood analysis. Supplement 1. A simplified and improved method for determination of sugar. Journal of Biological Chemistry 41 (1920) 367-374
9. Han D.H., Lee M.J., and Kim J.H. Antioxidant and apoptosis-inducing activities of ellagic acid. Anticancer Research 26 (2006) 3601-3606
10. Henry R.J. Clinical Chemistry: Principle and Techniques. 2nd ed. (1974), Harper and Row Publications, New York
11. Ito M., Shimura H., Watanabe N., Tamai M., Hanada K., Takahashi A., Tanaka Y., Arai K., Zhang P.L., Chang R., Chen W., Yang J., Su Y., and Wang Y. Hepatoprotective compounds from Canarium album and Euphorbia nematocypha. Chemical and Pharmaceutical Bulletin 38 (1990) 2201-2203
12. Jeong H.G. Inhibition of cytochrome P450 2E1 expression by oleanolic acid: hepatoprotective effects against carbon tetrachloride-induced hepatic injury. Toxicology Letters 105 (1999) 215-222
13. John Britto S., Soosairaj S., Natarajan D., Nagamurugan N., and Ravipaul S. Euphorbia fusiformis Buch.Ham.ex.D.Don (Euphorbiaceae): a new record of Tamil Nadu. Journal of Economic and Taxonomic Botany 26 (2002) 469-471
14. Kind P.R.N., and King E.J. Estimation of plasma phosphatase by determination of hydrolysed phenol amino-antipyrine. Journal of Clinical Pathology 7 (1954) 322-326
15. Lillie R.D. Histopathological Techniques and Practical Histochemistry (1965), McGrow Hill Book Company, New York
16. Loomis T.A., and Hayes A.W. Loomis's Essentials of Toxicology (1996), Academic Press, California
17. Lowry O.H., Rosebrough N.J., and Far A.L. Protein measurement with the Folin-Phenol reagent. Journal of Biological Chemistry 173 (1951) 265-275
18. Malloy H.T., and Evelyn K.A. The determination of bilirubin with the photoelectric colorimeter. Journal of Biological Chemistry 119 (1937) 481-490
19. Miller L.C., and Tainter M.L. Estimation of ED50 and its error. Proceedings of the Society for Experimental Biology and Medicine 57 (1949) 261-264
20. Naik S.R., and Panda V.S. Hepatoprotective effect of Ginkoselect phytosome in rifampicin induced liver injury in rats: evidence of antioxidant activity. Fitoterapia 79 (2008) 439-445
21. Natarajan D., John Britto S., Srinivasan K., Nagamurugan N., Mohanasundari C., and Perumal G. Antibacterial activity of Euphorbia fusiformis-a rare medicinal herb. Journal of Ethnopharmacology 102 (2005) 123-126
22. Pullaiah T. Medicinal Plants in India (2002), Regency Publications, New Delhi
23. Raju K., Natarajan S., Karuppusamy S., and Manian S. New ethnomedicinal report on Euphorbia fusiformis from Chitteri hills of Tamil Nadu, India. Journal of Swamy Botanical Club 21 (2004) 79-80
24. Reitman S., and Frankel S. A colorimetric method for the determination of serum glutamic oxaloacetic and glutamic-pyruvic transaminases. American Journal of Clinical Pathology 28 (1957) 56-63
25. Sakseena S., Rastogi R., Garg N.K., and Dhawan B.N. Rifampicin induced hepatotoxicity in rats: protective effect of picroliv. Drug Development Research 33 (1994) 46-50
26. Satti N.K., Suri O.P., Thaper R.K., and Kachroo P.L. Ent-atisane-3 beta, 16 alpha, 17-triol, a diterpene from Euphorbia acaulis. Phytochemistry 27 (1988) 1530-1531
27. Seeram N.P., Adams L.S., Henning S.M., Niu Y., Zhang Y., Nair M.G., and Heber D. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. Journal of Nutritional Biochemistry 16 (2005) 360-367
28. Singh G.B., Kaur S., Satti N.K., Atal C.K., and Maheshweri J.K. Antiinflammatory activity of Euphorbia acaulis Roxb. Journal of Ethnopharmacology 10 (1984) 225-233
29. Singh K., Khanna A.K., and Chander R. Hepatoprotective activity of ellagic acid against carbon tetrachloride induced hepatotoxicity in rats. Indian Journal of Experimental Biology 37 (1999) 1025-1026
30. Snider D.E., Long M.W., Cross F.S., and Farer L.S. Six months isoniazid-rifampicin therapy for pulmonary tuberculosis. Report of a United States Public Health service Co-operative trial. American Review of Respiratory Disease 129 (1984) 573-579
31. Steele M.A., Burk R.F., and DesPrez R.M. Toxic hepatitis with isoniazid and rifampicin. A meta-analysis. Chest 99 (1991) 465-471
32. Suri O.P., Satti N.K., Suri K.A., Dhar K.L., Kachroo P.L., Kawasaki T., Miyahara K., Tsunehiro T., and Funiko Y. An ent-secoatisane skeleton diterpene from a natural source, rhizomes of Euphorbia acaulis. Journal of Natural Products 53 (1990) 470-473
33. Szasz G. A kinetic photometric method for serum gamma-glutamyl transpeptidase. Clinical Chemistry 15 (1969) 124-136
34. Varley H., Gowerlock A.H., and Belt M. Practical Clinical Biochemistry (1980), William Heimann Medical Books Ltd., London
35. Vattem D.A., and Shetty K. Biological function of ellagic acid: a review. Journal of Biological Food Chemistry 29 (2005) 234-266
36. Weichselbaum T.E., Hagerty J.C., and Mark H.B. A reaction rate method for ammonia and blood urea nitrogen utilizing a pentacyanonitrosyloferrate catalyst Berthelot reactions. Analytical Chemistry 41 (1969) 848
37. WHO Scientific Group. Principles for Pre-clinical Testing of Drug Safety. Technical Report Series vol. 341 (1967), WHO, Geneva pp. 9-11