Extracellular loops 2 and 4 of GLYT2 are required for N-arachidonylglycine inhibition of glycine transport

Journal of Biological Chemistry

Volumn 284, Issue 52, 2009, Pages 36424-36430

  Edington, Amelia R ^a   McKinzie, Audra A ^a   Reynolds, Aaron J ^b,c   Kassiou, Michael ^b,c   Ryan, Renae M ^a   Vandenberg, Robert J ^a  

^a University of Sydney   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOBUTYRIC ACIDS; CENTRAL NERVOUS SYSTEMS; ENDOGENOUS INHIBITOR; EXTRACELLULAR; EXTRACELLULAR LOOPS; HEAD GROUPS; L-ALANINE; MOLECULAR BASIS; RAT MODEL; RELATED COMPOUNDS; SELECTIVE INHIBITION; SITE DIRECTED MUTAGENESIS; STRUCTURAL BASIS;

AMINO ACIDS; ORGANIC ACIDS; SODIUM;

ENZYME ACTIVITY;

AMINO ACID; GLYCINE TRANSPORTER 1; GLYCINE TRANSPORTER 2; N ARACHIDONYLGLYCINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; GENE MUTATION; NONHUMAN; OOCYTE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SENSITIVITY ANALYSIS; SITE DIRECTED MUTAGENESIS; XENOPUS LAEVIS;

ANIMALS; ARACHIDONIC ACIDS; BIOLOGICAL TRANSPORT; GLYCINE; GLYCINE PLASMA MEMBRANE TRANSPORT PROTEINS; MUTAGENESIS, SITE-DIRECTED; PAIN; PROTEIN STRUCTURE, SECONDARY; RATS; RECOMBINANT FUSION PROTEINS; XENOPUS LAEVIS;

RATTUS;

EID: 73649133989     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.017509     Document Type: Article

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