Effects of growth hormone treatment on growth in children with juvenile idiopathic arthritis

Hormone Research

Volumn 72, Issue SUPPL. 1, 2009, Pages 55-59

  Simon, D ^a   Bechtold, S ^b  

^a HÔPITAL ROBERT DEBRÉ   (France)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Glucocorticoids; Growth hormone; Growth retardation; Juvenile idiopathic arthritis

Indexed keywords

GLUCOCORTICOID; GROWTH HORMONE; PREDNISONE; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ADULT; ARTICLE; BODY HEIGHT; BONE GROWTH; BONE MINERALIZATION; CHILD; CHILD GROWTH; CLINICAL TRIAL; CONTROLLED STUDY; DELAYED PUBERTY; DISEASE DURATION; DRUG EFFECT; DRUG EFFICACY; GROWTH RATE; GROWTH RETARDATION; HORMONE RESPONSE; HORMONE SENSITIVITY; HORMONE SUBSTITUTION; HUMAN; INFLAMMATION; JUVENILE RHEUMATOID ARTHRITIS; LIPOLYSIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PUBERTY; TREATMENT OUTCOME;

ADOLESCENT; ARTHRITIS, JUVENILE RHEUMATOID; BODY HEIGHT; CHILD; CLINICAL TRIALS AS TOPIC; FOLLOW-UP STUDIES; GROWTH; GROWTH DISORDERS; HUMAN GROWTH HORMONE; HUMANS; TREATMENT OUTCOME;

EID: 73649127984     PISSN: 03010163     EISSN: None     Source Type: Journal    
DOI: 10.1159/000229765     Document Type: Article

References (18)

1. Zak M, Muller J, Karup Pedersen F: Final height, armspan, subischial leg length and body proportions in juvenile chronic arthritis. A long-term follow-up study. Horm Res 1999; 52: 80-85
2. Simon D, Fernando C, Czernichow P, Prieur AM: Linear growth and final height in patients with systemic juvenile idiopathic arthritis treated with longterm glucocorticoids. J Rheumatol 2002; 29: 1296-1300
3. Allen RC, Jimenez M, Cowell CT: Insulinlike growth factor and growth hormone secretion in juvenile chronic arthritis. Ann Rheum Dis 1991; 50: 602-606
4. Bennett AE, Silverman ED, Miller JJ 3rd, Hintz RL: Insulin-like growth factors i and ii in children with systemic onset juvenile arthritis. J Rheumatol 1988; 15: 655-658
5. Bergad PL, Schwarzenberg SJ, Humbert JT, Morrison M, Amarasinghe S, Towle HC, Berry SA: Inhibition of growth hormone action in models of inflammation. Am J Physiol Cell Physiol 2000; 279:C1906-C1917
6. Butenandt O: Rheumatoid arthritis and growth retardation in children: treatment with human growth hormone. Eur J Pediatr 1979; 130: 15-28
7. Svantesson H: Treatment of growth failure with human growth hormone in patients with juvenile chronic arthritis. A pilot study. Clin Exp Rheumatol 1991;9(suppl 6):47-50
8. Davies UM, Rooney M, Preece MA, Ansell BM, Woo P: Treatment of growth retardation in juvenile chronic arthritis with recombinant human growth hormone. J Rheumatol 1994; 21: 153-158
9. Touati G, Prieur AM, Ruiz JC, Noel M, Czernichow P: Beneficial effects of one-year growth hormone administration to children with juvenile chronic arthritis on chronic steroid therapy. I. Effects on growth velocity and body composition. J Clin Endocrinol Metab 1998; 83: 403-409
10. Simon D, Lucidarme N, Prieur AM, Ruiz JC, Czernichow P: Effects on growth and body composition of growth hormone treatment in children with juvenile idiopathic arthritis requiring steroid therapy. J Rheumatol 2003; 30: 2492-2499
11. Bechtold S, Ripperger P, Hafner R, Said E, Schwarz HP: Growth hormone improves height in patients with juvenile idiopathic arthritis: 4-year data of a controlled study. J Pediatr 2003; 143: 512-519
12. Simon D: rhGH treatment in corticosteroidtreated patients. Horm Res 2007; 68: 38-45
13. Bechtold S, Ripperger P, Dalla Pozza R, Bonfig W, Hafner R, Michels H, Schwarz HP: Growth hormone increases final height in patients with juvenile idiopathic arthritis: data from a randomized controlled study. J Clin Endocrinol Metab 2007; 92: 3013-3018
14. Jux C, Leiber K, Hugel U, Blum W, Ohlsson C, Klaus G, Mehls O: Dexamethasone impairs growth hormone (GH)-stimulated growth by suppression of local insulin-like growth factor (IGF)-I production and expression of GH-and IGF-I-receptor in cultured rat chondrocytes. Endocrinology 1998; 139: 3296-3305
15. Schrier L, Ferns SP, Barnes KM, Emons JA, Newman EI, Nilsson O, Baron J: Depletion of resting zone chondrocytes during growth plate senescence. J Endocrinol 2006; 189: 27-36
16. Mushtaq T, Farquharson C, Seawright E, Ahmed SF: Glucocorticoid effects on chondrogenesis, differentiation and apoptosis in the murine atdc5 chondrocyte cell line. J Endocrinol 2002; 175: 705-713
17. MacRae VE, Farquharson C, Ahmed SF: The restricted potential for recovery of growth plate chondrogenesis and longitudinal bone growth following exposure to pro-inflammatory cytokines. J Endocrinol 2006; 189: 319-328
18. Simon D, Prieur AM, Quartier P, Charles Ruiz J, Czernichow P: Early recombinant human growth hormone treatment in glucocorticoid-treated children with juvenile idiopathic arthritis: a 3-year randomized study. J Clin Endocrinol Metab 2007; 92: 2567-2573