Early recombinant human growth hormone treatment in glucocorticoid-treated children with juvenile idiopathic arthritis: A 3-year randomized study

Journal of Clinical Endocrinology and Metabolism

Volumn 92, Issue 7, 2007, Pages 2567-2573

  Simon, Dominique ^a   Prieur, Anne Marie ^b   Quartier, Pierre ^b   Ruiz, Jean Charles ^c   Czernichow, Paul ^a  

^a HÔPITAL ROBERT DEBRÉ   (France)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

^c Cochin Teaching Hospital ^*  (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID; GLUCOSE; HUMAN GROWTH HORMONE; INSULIN; PREDNISONE; SOMATREM;

ARTICLE; BODY COMPOSITION; BODY HEIGHT; BONE MINERALIZATION; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DIET RESTRICTION; DRUG EFFECT; DRUG SCREENING; FAT BODY; FEMALE; GLUCOSE BLOOD LEVEL; GROWTH DISORDER; GROWTH RATE; HORMONAL THERAPY; HUMAN; IDIOPATHIC DISEASE; INSULIN BLOOD LEVEL; JUVENILE RHEUMATOID ARTHRITIS; LONG TERM CARE; MALE; MEASUREMENT; ORAL GLUCOSE TOLERANCE TEST; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SIDE EFFECT; STATISTICAL SIGNIFICANCE; TREATMENT DURATION;

EID: 34447114514     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2006-2877     Document Type: Article

References (37)

1. Simon D, Fernando C, Czernichow P, Prieur AM 2002 Linear growth and final height in patients with systemic juvenile chronic arthritis treated with long-term glucocorticoids. J Rheumatol 29:1296-1300
2. Davies UM, Rooney M, Preece MA, Ansell BM, Woo P 1994 Treatment of growth retardation in juvenile chronic arthritis with recombinant human growth hormone. J Rheumatol 21:153-158
3. Touati G, Prieur AM, Ruiz JC, Noel M, Czernichow P 1998 Beneficial effects of one-year growth hormone administration to children with juvenile chronic arthritis on chronic steroid therapy. I. Effects on growth velocity and body composition. J Clin Endocrinol Metab 83:403-409
4. Bechtold S, Ripperger P, Mühlbayer D, Truckenbrodt H, Häfner R, Butenandt O, Schwarz HP 2001 GH therapy in juvenile chronic arthritis: results of a two-year controlled study on growth and bone. J Clin Endocrinol Metab 86:5737-5744
5. Simon D, Lucidarme N, Prieur AM, Ruiz JC, Czernichow P 2003 Effects on growth and body composition of growth hormone treatment in children with juvenile idiopathic arthritis requiring steroid therapy. J Rheumatol 30:2492-2499
6. Touati G, Ruiz JC, Porquet D, Kindermans C, Prieur AM, Czernichow P 2000 Effects on bone metabolism of one year recombinant human growth hormone administration to children with juvenile chronic arthritis undergoing chronic steroid therapy. J Rheumatol 27:1287-1293
7. Bechtold S, Ripperger P, Häfner R, Said E, Schwartz HP 2003 Growth hormone improves height in patients with juvenile idiopathic arthritis: 4-year data of a controlled study. J Pediatr 143:512-519
8. Bechtold S, Ripperger P, Bonfig W, Schmidt H, Bitterling H, Häfner R, Schwarz H 2004 Bone mass development and bone metabolism in juvenile idiopathic arthritis: treatment with growth hormone for 4 years. J Rheumatol 31:1407-1412
9. Bechtold S, Ripperger P, Bonfig W, Dalla Pozza R, Häfner R, Schwarz H 2005 Growth hormone changes bone geometry and body composition in patients with juvenile idiopathic arthritis requiring glucocorticoid treatment: a controlled study using peripheral quantitative computed tomography. J Clin Endocrinol Metab 90:3168-3173
10. Davies UM, Jones J, Reeve J, Camacho-Hubner C, Charlett A, Ansell BM, Preece M, Woo P 1997 Effects of disease activity and recombinant human growth hormone on insulin-like growth factor 1, insulin-like growth factor binding proteins 1 and 3, and osteocalcin. Arthritis Rheum 40:332-340
11. Jux C, Leiber K, Hügel U, Blum W, Ohlsson C, Klaus G, Mehls O 1998 Dexamethasone impairs growth hormone (GH)-stimulated growth by suppression of local insulin-like growth factor (IGF)-I production and expression of GH- and IGF-I-receptor in cultured rat chondrocytes. Endocrinology 139:3296-3305
12. Schrier L, Ferns SP, Barnes KM, Emons JAM, Newman EI, Nilsson O, Baron J 2006 Depletion of resting zone chondrocytes during growth plate senescence. J Endocrinol 189:27-36
13. Mushtaq T, Farquharson C, Seawright E, Ahmed SF 2002 Glucocorticoid effects on chondrogenesis, differentiation and apoptosis in the murine ATDC5 chondrocyte cell line. J Endocrinol 175:705-713
14. MacRae VE, Farquharson C, Ahmed SF 2006 The restricted potential for recovery of growth plate chondrogenesis and longitudinal bone growth following exposure to pro-inflammatory cytokines. J Endocrinol 189:319-328
15. Petty RE, Southwood TR, Baum J, Bhettay E, Glass DN, Manners P, Maldonado-Cocco J, Suarez-Almazor M, Orozco-Alcala J, Prieur AM 1998 Revision of the proposed classification criteria for juvenile idiopathic arthritis: Durban, 1997. J Rheumatol 25:1991-1994
16. Tanner JM, Whitehouse RH 1976 Clinical longitudinal standards for height, weight, height velocity and stages of puberty. Arch Dis Child 51:170-179
17. Sempé M, Pédron G, Pernot MP 1979 Auxologie: méthodes et séquences. Paris: Théraplix
18. Rolland-Cachera MF, Cole TJ, Sempé M, Tichet J, Rossignol C, Chanaud A 1991 Body mass index variations: centiles from birth to 87 years. Eur J Clin Nutr 45:13-21
19. Greulich WW, Pyle SI, eds. 1959 Radiographic atlas of skeletal development of the hand and wrist. 2nd ed. Stanford, CA: Stanford University Press
20. Braillon PM, Bérard J, Chatelain P, Pracros JP 2002 Dual energy x-ray absorptiometry assessment of the bone mineral content and body composition during growth. J Radiol 83:627-633
21. Ruiz JC, Mandel C, Garabedian M 1995 Influence of spontaneous calcium intake and physical exercise on the vertebral and femoral bone mineral density of children and adolescents. J Bone Miner Res 10: 675-682
22. Kroger H, Kotaniemi A, Vainio P, Alhava E 1992 Bone densitometry of the spine and femur in children by dual-energy x-ray absorptiometry. Bone Miner 17:75-85
23. American Diabetes Association 2004 Diagnosis and classification of diabetes mellitus. Diabetes Care 27:S5-S10
24. Allen RC, Jimenez M, Cowell T 1991 Insulin-like growth factor and growth hormone secretion in juvenile chronic arthritis. Ann Rheum Dis 50:602-606
25. Allen DB, Julius JR, Breen TJ, Attie KM 1998 Treatment of glucocorticoid-induced growth suppression with growth hormone. J Clin Endocrinol Metab 83: 2824-2829
26. Thissen JP, Verniers J 1997 Inhibition by interleukin-1β and tumor necrosis factor-α of the insulin-like growth factor I messenger ribonucleic acid response to growth hormone in rat hepatocyte primary culture. Endocrinology 138:1078-1084
27. Bergad PL, Schwarzenberg SJ, Humbert JT, Morrison M, Amarasinghe S, Towle HC, Berry SA 2000 Inhibition of growth hormone action in models of inflammation. Am J Physiol Cell Physiol 279:C1906-C1917
28. Yumet G, Shumate ML, Bryant P, Lin CM, Lang CH, Cooney RN 2002 Tumor necrosis factor mediates hepatic growth hormone resistance during sepsis. Am J Physiol Endocrinol Metab 283:E472-E481
29. Tynjala P, Lahdenne P, Vahasalo P, Kautiainen H, Honkanen V 2006 Impact of anti-TNF treatment on growth in severe juvenile idiopathic arthritis. Ann Rheum Dis 65:1044-1049
30. Quartier P, Taupin P, Bourdeault F, Lemelle I, Pillet P, Bost M, Sibilia J, Kone-Paut I, Gandon-Laloum S, Le Bideau M, Bader-Meunier B, Mouy R, Debré M, Landias P, Prieur AM 2003 Efficacy of etanercept for the treatment of juvenile idiopathic arthritis according to the onset type. Arthritis Rheum 48:1093-1101
31. Lien G, Selvaag AM, Flato B, Haugen M, Vinje O, Sorskaar D, Dale K, Egeland T, Forre O 2005 A two-year prospective controlled study of bone mass and bone turnover in children with early juvenile idiopathic arthritis. Arthritis Rheum 52:833-840
32. Frost HM, Schönau E 2000 The "muscle-bone unit" in children and adolescents: a 2000 overview. J Pediatr Endocrinol Metab 13:571-590
33. Steiger U, Lippuner K, Jensen EX, Montandon A, Jaeger Ph, Horber FF 1995 Body composition and fuel metabolism after kidney grafting. Eur J Clin Invest 25:809-816
34. Horber FF, Marsh HM, Haymond MW 1991 Differential effects of prednisone and growth hormone on fuel metabolism and insulin antagonism in humans. Diabetes 40:141-149
35. Bratusch-Marrain PR, Smith D, DeFronzo RA 1982 The effect of growth hormone on glucose metabolism and insulin secretion in man. J Clin Endocrinol Metab 55:973-982
36. Tsigos C, Papanicolaou DA, Kyrou I, Defensor R,. Mitsiadis CS, Chrousos GP 1997 Dose-dependent effects of recombinant human interleukin-6 on glucose regulation. J Clin Endocrinol Metab 82:4167-4170
37. Pittas AG, Joseph AN, Greenberg AS 2004 Adipocytokines and insulin resistance. J Clin Endocrinol Metab 89:447-452