Pre- and postnatal developmental toxicity study design for pharmaceuticals

Birth Defects Research Part B - Developmental and Reproductive Toxicology

Volumn 86, Issue 6, 2009, Pages 437-445

  Bailey, Graham P ^a   Wise, L David ^b   Buschmann, Jochen ^c   Hurtt, Mark ^d   Fisher, J Edward ^e  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^b MERCK RESEARCH LABORATORIES   (United States)

^c FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

^d PFIZER INC   (United States)

^e CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Hazard assessment; Neonatal development; Postnatal developmental toxicity; Prenatal; Safety assessment

Indexed keywords

BIRTH; BODY WEIGHT; DRUG INDUSTRY; EMBRYOTOXICITY; FERTILITY; FOOD INTAKE; GENITAL SYSTEM; HAZARD ASSESSMENT; LACTATION; LEARNING; LIBIDO; MEMORY; MOTOR ACTIVITY; NONHUMAN; POSTNATAL DEVELOPMENT; PRENATAL DEVELOPMENT; PRIORITY JOURNAL; REVIEW; SEXUAL DEVELOPMENT; TERATOGENICITY; TOXICOKINETICS; TOXICOLOGY;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYONIC DEVELOPMENT; FETAL DEVELOPMENT; GROWTH AND DEVELOPMENT; INTERNATIONAL AGENCIES; INTERNATIONAL COOPERATION; LEGISLATION, DRUG; MICE; PHARMACEUTICAL PREPARATIONS; RATS; RESEARCH DESIGN; RISK ASSESSMENT; TOXICITY TESTS;

RATTUS; RODENTIA;

EID: 73649109536     PISSN: 15429733     EISSN: None     Source Type: Journal    
DOI: 10.1002/bdrb.20217     Document Type: Review

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