Mechanism of an amphipathic α-helical peptide's antiviral activity involves size-dependent virus particle lysis

ACS Chemical Biology

Volumn 4, Issue 12, 2009, Pages 1061-1067

  Cho, Nam Joon ^a   Dvory Sobol, Hadas ^a   Xiong, Anming ^a   Cho, Sang Joon ^d   Frank, Curtis W ^c   Glenn, Jeffrey S ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

^c Stanford University   (United States)

^d Park Systems Corp   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; HISTIDYLSERYLGLYCYLSERYLTRYPTOPHYLLEUCYLARGINYLASPARTYL ASPARTYLTRYPTOPHYLASPARTYLTRYPTOPHYLGLUTAMYLCYSTEINYLTHREONYL VALYLLEUCYLTHREONYLASPARTYLASPARTYLLYSYLTHREONYLTRYPTOPHYLLEUCYL GLUTAMINYLSERYLLYSYLLEUCINAMIDE; HISTIDYLSERYLGLYCYLSERYLTRYPTOPHYLLEUCYLARGINYLASPARTYLVALYL TRYPTOPHYLASPARTYLTRYPTOPHYLISOLEUCYLCYSTEINYLTHREONYLVALYLLEUCYLTHREONYL ASPARTYLPHENYLALANYLLYSYLTHREONYLTRYPTOPHYLLEUCYLGLUTAMINYLSERYLLYSYLLEUCINAMIDE; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ALPHA HELIX; ANTIVIRAL ACTIVITY; ARTICLE; ATOMIC FORCE MICROSCOPY; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG MECHANISM; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IN VITRO STUDY; LIGHT SCATTERING; LIPID VESICLE; LIPOLYSIS; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; QUARTZ CRYSTAL MICROBALANCE; VACCINIA VIRUS; VIRUS INFECTIVITY; VIRUS PARTICLE;

AMINO ACID SEQUENCE; ANTIVIRAL AGENTS; HEPACIVIRUS; HEPATITIS C; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; VIRAL NONSTRUCTURAL PROTEINS; VIRION;

HEPATITIS C VIRUS;

EID: 73649095844     PISSN: 15548929     EISSN: None     Source Type: Journal    
DOI: 10.1021/cb900149b     Document Type: Article

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