Synthesis of nitroimidazole derived oxazolidinones as antibacterial agents

European Journal of Medicinal Chemistry

Volumn 45, Issue 2, 2010, Pages 661-666

  Varshney, Vandana ^a   Mishra, Nripendra N ^a   Shukla, Praveen K ^a   Sahu, Devi P ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Antibacterial; Linezolid; Nitroimidazoles; Oxazolidinone

Indexed keywords

ANTIINFECTIVE AGENT; LINEZOLID; N [3 (3 FLUORO 4 [4 [2 (2 METHYL 5 NITRO IMIDAZOL 1 YL)ETHYL]PIPERAZIN 1 YL]PHENYL] 2 OXO OXAZOLIDIN 5 YLMETHYL]ACETAMIDE; N [3 [3 FLUORO 4 [4 [2 (2 METHYL 5 NITRO IMIDAZOL 1 YL)ACETYL]PIPERAZIN 1 YL]PHENYL) 2 OXO OXAZOLIDIN 5 YLMETHYL]ACETAMIDE; N [3 [3 FLUORO 4 [4 [2 (2 NITRO IMIDAZOL 1 YL)ETHYL]PIPERAZIN1YL]PHENYL] 2 OXO OXAZOLIDIN 5 YLMETHYL]ACETAMIDE; N [3 [3 FLUORO 4 [4 [2 (4 NITRO IMIDAZOL 1 YL)ACETYL]PIPERAZIN 1 YL]PHENYL] 2 OXO OXAZOLIDIN 5 YLMETHYL]ACETAMIDE; N [3 [3 FLUORO 4 [4 [2 (4 NITRO IMIDAZOL 1 YL)ETHYL]PIPERAZIN 1 YL]PHENYL] 2 OXO OXAZOLIDIN 5 YLMETHYL]ACETAMIDE; N [3 [3 FLUORO 4 [4 [2 HYDROXY 3 (2 METHYL 5 NITROIMIDAZOL 1 YL)PROPYL]PIPERAZIN 1 YL]PHENYL) 2 OXO OXAZOLIDIN 5 YLMETHYL]ACETAMIDE; N [3 [3 FLUORO 4 [4 [2 HYDROXY 3 (4 NITRO IMIDAZOL 1 YL)PROPYL]PIPERAZIN 1 YL]PHENYL) 2 OXO OXAZOLIDIN 5 YLMETHYL]ACETAMIDE; N [3 [3 FLUORO 4 [4 [3 (2 METHYL 5 NITRO IMIDAZOL 1 YL)PROPYL]PIPERAZIN 1 YL]PHENYL] 2 OXO OXAZOLIDIN 5 YLMETHYL]ACETAMIDE; N [3 [3 FLUORO 4 [4 [3 (2 NITRO IMIDAZOL 1 YL)PROPYL]PIPERAZIN 1 YL]PHENYL] 2 OXO OXAZOLIDIN 5 YLMETHYL]ACETAMIDE; NITROIMIDAZOLE DERIVATIVE; OXAZOLIDINONE DERIVATIVE; UNCLASSIFIED DRUG; VANCOMYCIN;

ALKYLATION; ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACILLUS CEREUS; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; ESCHERICHIA; IN VITRO STUDY; KLEBSIELLA PNEUMONIAE; MOUSE; NONHUMAN; PSEUDOMONAS AERUGINOSA; STREPTOCOCCUS PYOGENES;

ALKYLATION; ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIA; CELL LINE; CELL SURVIVAL; DRUG RESISTANCE, BACTERIAL; MICE; NITROIMIDAZOLES; OXAZOLIDINONES;

EID: 73549121712     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.11.009     Document Type: Article

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