NADPH oxidases and atherosclerosis: Unraveling the details

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 298, Issue 1, 2010, Pages

  Madamanchi, Nageswara R ^a   Runge, Marschall S ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2;

ATHEROGENESIS; ATHEROSCLEROSIS; EDITORIAL; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; VASCULAR DISEASE; VASCULAR SMOOTH MUSCLE; VASCULARIZATION;

ADULT; AGED; APOLIPOPROTEINS E; ATHEROSCLEROSIS; HUMANS; ISOENZYMES; MIDDLE AGED; NADPH OXIDASE; PHAGOCYTES; REACTIVE OXYGEN SPECIES;

EID: 73549107847     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01020.2009     Document Type: Editorial

References (12)

1. Ambasta RK, Schreiber JG, Janiszewski M, Busse R, Brandes RP. Noxa1 is a central component of the smooth muscle NADPH oxidase in mice. Free Radic Biol Med 41: 193-201, 2006.
2. Ballinger SW, Patterson C, Knight-Lozano CA, Burow DL, Conklin CA, Hu Z, Reuf J, Horaist C, Lebovitz R, Hunter GC, McIntyre K, Runge MS. Mitochondrial integrity and function in atherogenesis. Circulation 106: 544-549, 2002.
3. -/- mice. J Clin Invest 108: 1513-1522, 2001.
4. Gavazzi G, Banfi B, Deffert C, Fiette L, Schappi M, Herrmann F, Krause KH. Decreased blood pressure in NOX1-deficient mice. FEBS Lett 80: 497-504, 2006.
5. Jaquet V, Scapozza L, Clark RA, Krause KH, Lambeth JD. Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets. Antioxid Redox Signal 11: 2535-2552, 2009.
6. -/- mice. Am J Physiol Heart Circ Physiol (October 16, 2009). doi:10.1152/ajpheart.00799. 2009.
7. Lee MY, San Martin A, Mehta PK, Dikalova AE, Garrido AM, Datla SR, Lyons E, Krause KH, Banfi B, Lambeth JD, Lassègue B, Griendling KK. Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation. Arterioscler Thromb Vasc Biol 29: 480-487, 2009.
8. Lyle AN, Deshpande NN, Taniyama Y, Seidel-Rogol B, Pounkova L, Du P, Papaharalambus C, Lassègue B, Griendling KK. Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells. Circ Res 105: 249-259, 2009.
9. Niu XL, Madamanchi NR, Vendrov AE, Tchivilev I, Rojas M, Madamanchi C, Brandes RP, Krause KH, Smith A, Burnand KG, Runge MS. Nox activator 1 (NoxA1): a potential target for modulation of vascular reactive oxygen species in atherosclerotic arteries. Circulation. In press.
10. Schröder K, Wandzioch K, Helmcke I, Brandes RP. Nox4 acts as a switch between differentiation and proliferation in preadipocytes. Arterioscler Thromb Vasc Biol 29: 239-245, 2009.
11. Suh YA, Arnold RS, Lassegue B, Shi J, Xu X, Sorescu D, Chung AB, Griendling KK, Lambeth JD. Cell transformation by the superoxide-generating oxidase Mox1. Nature 401: 79-82, 1999.
12. Vendrov AE, Hakim ZS, Madamanchi NR, Rojas M, Madamanchi C, Runge MS. Atherosclerosis is attenuated by limiting superoxide generation in both macrophages and vessel wall cells. Arterioscler Thromb Vasc Biol 27: 2714-2721, 2007.