Glycolic acid modulates the mechanical property and degradation of poly(glycerol, sebacate, glycolic acid)

Journal of Biomedical Materials Research - Part A

Volumn 92, Issue 1, 2010, Pages 332-339

  Sun, Zhi Jie ^a   Wu, Lan ^a   Huang, Wei ^b   Chen, Chang ^b   Chen, Yan ^b   Lu, Xi Li ^a   Zhang, Xiao Lan ^b   Yang, Bao Feng ^b   Dong, De Li ^b  

^a HARBIN ENGINEERING UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Anticoagulant; Cross linking; Degradation; Mechanical properties; Microstructure

Indexed keywords

ANTICOAGULANT; BIODEGRADABLE MATERIAL; CONTROLLABLE DEGRADATION; DEGRADATION RATE; DEGREE OF CROSSLINKING; DEGREE OF ORDERING; GLYCOLIC ACIDS; IN-VITRO; MELTING PEAK; MOLE RATIO; PHASE SEPARATION STRUCTURE; TISSUE RESPONSE;

ACIDS; BIOLOGICAL MATERIALS; CROSSLINKING; DEGRADATION; DOPING (ADDITIVES); GLYCEROL; MICROSTRUCTURE; PHASE SEPARATION;

MECHANICAL PROPERTIES;

BIOMATERIAL; GLYCEROL; GLYCOLIC ACID; POLYMER; SEBACIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTICOAGULATION; ARTICLE; BLOOD CLOTTING TIME; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; CONTROLLED STUDY; CROSS LINKING; CRYSTAL STRUCTURE; MELTING POINT; NONHUMAN; PHASE SEPARATION; THROMBOCYTE ADHESION;

ANIMALS; CALORIMETRY, DIFFERENTIAL SCANNING; CRYSTALLIZATION; DECANOATES; ELASTIC MODULUS; GLASS; GLYCEROL; GLYCOLATES; HYDROGEN-ION CONCENTRATION; IMPLANTS, EXPERIMENTAL; MATERIALS TESTING; MECHANICAL PHENOMENA; MOLECULAR WEIGHT; PLATELET ADHESIVENESS; POLYESTERS; POLYMERS; RABBITS; RATS; RATS, WISTAR; SPECTROPHOTOMETRY, INFRARED; TEMPERATURE; THROMBOSIS; WHOLE BLOOD COAGULATION TIME; X-RAY DIFFRACTION;

EID: 73549103369     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32370     Document Type: Article

References (8)

1. Wang Y, Ameer GA, Sheppard BJ, Langer R. A tough biodegradable elastomer. Nat Biotechnol 2002;20:602-606.
2. Sundback CA, Shyu JY, Wang Y, Faquin WC, Langer RS, Vacanti JP, Hadlock TA. Biocompatibility analysis of poly (glycerol sebacate) as a nerve guide material. Biomaterials 2005;26:5454-5464.
3. Chen QZ, Bismarck A, Hansen U, Junaid S, Tran MQ, Harding SE, Ali NN, Boccaccini AR. Characterisation of a soft elastomer poly(glycerol sebacate) designed to match the mechanical properties of myocardial tissue. Biomaterials 2008;29:47-57.
4. Fidkowski C, Kaazempur-Mofrad MR, Borenstein J, Vacanti JP, Langer R, Wang Y. Endothelialized microvasculature based on a biodegradable elastomer. Tissue Eng 2005;11:302-309.
5. Wang Y, Kim YM, Langer R. In vivo degradation characteristics of poly(glycerol sebacate). J Biomed Mater Res A 2003;66:192-197.
6. Sundback CA, Shyu JY, Wang Y, Faquin WC, Langer RS, Vacanti JP, Hadlock TA. Biocompatibility analysis of poly(glycerol sebacate) as a nerve guide material. Biomaterials 2005;26:5454-5456.
7. Motlagh D, Yang J, Lui KY, Webb AR, Ameer GA. Hemocompatibility evaluation of poly(glycerol-sebacate) in vitro for vascular tissue engineering. Biomaterials 2006;27:4315-4324.
8. Oliver WC, Pharr GM. An improved technique for determining hardness and elastic modulus using load and displacement sensing indentation experiments. J Mater Res 1992;7:1564-1583.