Making the case for early treatment of acne

Clinical Pediatrics

Volumn 49, Issue 1, 2010, Pages 54-59

  Zaenglein, Andrea L ^a  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

Acne vulgaris; Early acne; Mild to moderate acne; Treatment options

Indexed keywords

ADAPALENE; ANTIBIOTIC AGENT; AZELAIC ACID; BENZOYL PEROXIDE; CLINDAMYCIN; ERYTHROMYCIN; ISOTRETINOIN; RETINOID; SALICYLIC ACID; SULFACETAMIDE; TAZAROTENE; ZINC;

ACNE; ALGORITHM; CLINICAL TRIAL; CONTACT DERMATITIS; DISEASE CLASSIFICATION; DOSAGE SCHEDULE COMPARISON; DRUG EFFICACY; DRUG FORMULATION; DRUG SAFETY; HUMAN; PREDICTIVE VALIDITY; PRESCRIPTION; REVIEW; ROSACEA; SCAR FORMATION; SKIN IRRITATION; TREATMENT OUTCOME;

ACNE VULGARIS; ADOLESCENT; DERMATOLOGIC AGENTS; HUMANS; QUALITY OF LIFE; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 73549084054     PISSN: 00099228     EISSN: None     Source Type: Journal    
DOI: 10.1177/0009922809342462     Document Type: Review

References (40)

1. White GM Recent findings in the epidemiologic evidence, classification, and subtypes of acne vulgaris. J Am Acad Dermatol. 1998 ; 39 (2, pt 3). S34 - S37.
2. Webster GF Is it reasonable for a dermatologist to treat acne ? Arch Dermatol. 1996 ; 132: 819-820.
3. Stern RS Acne therapy. Medication use and sources of care in office-based practice. Arch Dermatol. 1996 ; 132: 776-780.
4. Resneck J. Jr, Kimball AB The dermatology workforce shortage. J Am Acad Dermatol. 2004 ; 50: 50-54.
5. Fried RG, Wechsler A. Psychological problems in the acne patient. Dermatol Ther. 2006 ; 19: 237-240.
6. Kellett SC, Gawkrodger DJ The psychological and emotional impact of acne and the effect of treatment with isotretinoin. Br J Dermatol. 1999 ; 140: 273-282.
7. Gupta MA, Gupta AK Depression and suicidal ideation in dermatology patients with acne, alopecia areata, atopic dermatitis and psoriasis. Br J Dermatol. 1998 ; 139: 846-850.
8. Smithard A., Glazebrook C., Williams HC Acne prevalence, knowledge about acne and psychological morbidity in mid-adolescence: a community-based study. Br J Dermatol. 2001 ; 145: 274-279.
9. Pearl A., Arroll B., Lello J., Birchall NM The impact of acne: a study of adolescents attitudes, perception and knowledge. N Z Med J. 1998 ; 111: 269-271.
10. Reich A., Jasiuk B., Samotij D., Tracinska A., Trybucka K., Szepietowski JC Acne vulgaris: what teenagers think about it. Dermatol Nurs. 2007 ; 19: 49-54, 64.
11. Marks R. Acne: social impact and health education. J R Soc Med. 1985 ; 78 (suppl 10). 21-24.
12. Layton AM, Henderson CA, Cunliffe WJ A clinical evaluation of acne scarring and its incidence. Clin Exp Dermatol. 1994 ; 19: 303-308.
13. Holland DB, Jeremy AH, Roberts SG, Seukeran DC, Layton AM, Cunliffe WJ Inflammation in acne scarring: a comparison of the responses in lesions from patients prone and not prone to scar. Br J Dermatol. 2004 ; 150: 72-81.
14. Gupta MA, Gupta AK, Schork NJ Psychosomatic study of self-excoriative behavior among male acne patients: preliminary observations. Int J Dermatol. 1994 ; 33: 846-848.
15. Bulengo-Ransby SM, Griffiths CE, Kimbrough-Green CK, et al. Topical tretinoin (retinoic acid) therapy for hyperpigmented lesions caused by inflammation of the skin in black patients. N Engl J Med. 1993 ; 328: 1438-1443.
16. Lucky AW, Biro FM, Simbartl LA, Morrison JA, Sorg NW Predictors of severity of acne vulgaris in young adolescent girls: results of a five-year longitudinal study. J Pediatr. 1997 ; 130: 30-39.
17. Bataille V., Snieder H., MacGregor AJ, Sasieni P., Spector TD The influence of genetics and environmental factors in the pathogenesis of acne: a twin study of acne in women. J Invest Dermatol. 2002 ; 119: 1317-1322.
18. Goulden V., McGeown CH, Cunliffe WJ The familial risk of adult acne: a comparison between first-degree relatives of affected and unaffected individuals. Br J Dermatol. 1999 ; 141: 297-300.
19. Gollnick H., Cunliffe W., Berson D., et al. Management of acne: a report from a Global Alliance to Improve Outcomes in Acne. J Am Acad Dermatol. 2003 ; 49 (1 suppl). S1 - S37.
20. Tschen E. Addressing patient variability: clinical challenges in the initiation of acne treatment. Cutis. 2008 ; 82 (2 suppl). 9-17.
21. Toyoda M., Morohashi M. An overview of topical antibiotics for acne treatment. Dermatology. 1998 ; 196: 130-134.
22. Tan HH Topical antibacterial treatments for acne vulgaris: comparative review and guide to selection. Am J Clin Dermatol. 2004 ; 5: 79-84.
23. Ross JI, Snelling AM, Carnegie E., et al. Antibiotic-resistant acne: lessons from Europe. Br J Dermatol. 2003 ; 148: 467-478.
24. Eady AE, Cove JH, Layton AM Is antibiotic resistance in cutaneous propionibacteria clinically relevant? Implications of resistance for acne patients and prescribers. Am J Clin Dermatol. 2003 ; 4: 813-831.
25. Eady EA, Bojar RA, Jones CE, Cove JH, Holland KT, Cunliffe WJ The effects of acne treatment with a combination of benzoyl peroxide and erythromycin on skin carriage of erythromycin-resistant propionibacteria. Br J Dermatol. 1996 ; 134: 107-113.
26. Leyden J., Kaidbey K., Levy SF The combination formulation of clindamycin 1% plus benzoyl peroxide 5% versus 3 different formulations of topical clindamycin alone in the reduction of Propionibacterium acnes: an in vivo comparative study. Am J Clin Dermatol. 2001 ; 2: 263-266.
27. Packman AM, Brown RH, Dunlap FE, Kraus SJ, Webster GF Treatment of acne vulgaris: combination of 3% erythromycin and 5% benzoyl peroxide in a gel compared to clindamycin phosphate lotion. Int J Dermatol. 1996 ; 35: 209-211.
28. Lookingbill DP, Chalker DK, Lindholm JS, et al. Treatment of acne with a combination clindamycin/benzoyl peroxide gel compared with clindamycin gel, benzoyl peroxide gel and vehicle gel: combined results of two double-blind investigations. J Am Acad Dermatol. 1997 ; 37: 590-595.
29. Leyden JJ The evolving role of Propionibacterium acnes in acne. Semin Cutan Med Surg. 2001 ; 20: 139-143.
30. Webster GF, Guenther L., Poulin YP, Solomon BA, Loven K., Lee J. A multicenter, double-blind, randomized comparison study of the efficacy and tolerability of once-daily tazarotene 0.1% gel and adapalene 0.1% gel for the treatment of facial acne vulgaris. Cutis. 2002 ; 69 (2 suppl). 4-11.
31. Shalita A., Miller B., Menter A., Abramovits W., Loven K., Kakita L. Tazarotene cream versus adapalene cream in the treatment of facial acne vulgaris: a multicenter, double-blind, randomized, parallel-group study. J Drugs Dermatol. 2005 ; 4: 153-158.
32. Kakita L. Tazarotene versus tretinoin or adapalene in the treatment of acne vulgaris. J Am Acad Dermatol. 2000 ; 43 (2, pt 3). S51 - S54.
33. Cunliffe WJ, Poncet M., Loesche C., Verschoore M. A comparison of the efficacy and tolerability of adapalene 0.1% gel versus tretinoin 0.025% gel in patients with acne vulgaris: a meta-analysis of five randomized trials. Br J Dermatol. 1998 ; 139 (suppl 52). 48-56.
34. Nyirady J., Grossman RM, Nighland M., et al. A comparative trial of two retinoids commonly used in the treatment of acne vulgaris. J Dermatolog Treat. 2001 ; 12: 149-157.
35. Leyden JJ, Tanghetti EA, Miller B., Ung M., Berson D., Lee J. Once-daily tazarotene 0.1 % gel versus once-daily tretinoin 0.1% microsponge gel for the treatment of facial acne vulgaris: a double-blind randomized trial. Cutis. 2002 ; 69 (2 suppl). 12-19.
36. Tazorac Gel [package insert]. Irvine, CA: Allergan, Inc; 2008.
37. Andres P., Pernin C., Poncet M. Adapalene-benzoyl peroxide once-daily, fixed-dose combination gel for the treatment of acne vulgaris: a randomized, bilateral (split-face), dose-assessment study of cutaneous tolerability in healthy participants. Cutis. 2008 ; 81: 278-284.
38. Schlessinger J., Menter A., Gold M., et al. Clinical safety and efficacy studies of a novel formulation combining 1.2% clindamycin phosphate and 0.025% tretinoin for the treatment of acne vulgaris. J Drugs Dermatol. 2007 ; 6: 607-615.
39. Breneman DL, Ariano MC Successful treatment of acne vulgaris in women with a new topical sodium sulfacetamide/ sulfur lotion. Int J Dermatol. 1993 ; 32: 365-367.
40. Thiboutot D. Versatility of azelaic acid 15% gel in treatment of inflammatory acne vulgaris. J Drugs Dermatol. 2008 ; 7: 13-16.