Inflammation in acne scarring: A comparison of the responses in lesions from patients prone and not prone to scar

British Journal of Dermatology

Volumn 150, Issue 1, 2004, Pages 72-81

  Holland, D B ^a   Jeremy, A H T ^a   Roberts, S G ^a   Seukeran, D C ^b   Layton, A M ^c   Cunliffe, W J ^a  

^a LEEDS GENERAL INFIRMARY   (United Kingdom)

^b JAMES COOK UNIVERSITY HOSPITAL   (United Kingdom)

^c HARROGATE DISTRICT HOSPITAL   (United Kingdom)

Author keywords

Acne; Macrophages; Scarring; Skin homing memory effector t cells

Indexed keywords

CELL MARKER; HLA DR ANTIGEN; VASCULAR CELL ADHESION MOLECULE 1;

ACNE; ADULT; ANGIOGENESIS; ANTIGEN EXPRESSION; ARTICLE; BACK; BLOOD VESSEL; CELL COUNT; CELLULAR IMMUNITY; CONTROLLED STUDY; EFFECTOR CELL; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LANGERHANS CELL; LEUKOCYTE; MACROPHAGE; MALE; MEMORY CELL; PRIORITY JOURNAL; SKIN BIOPSY; SKIN INFLAMMATION; SKIN SCAR; T LYMPHOCYTE;

ACNE VULGARIS; ADOLESCENT; ADULT; CELL ADHESION MOLECULES; CICATRIX; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HLA-DR ANTIGENS; HUMANS; IMMUNITY, CELLULAR; IMMUNOENZYME TECHNIQUES; INFLAMMATION; LANGERHANS CELLS; MACROPHAGES; MALE; T-LYMPHOCYTE SUBSETS;

EID: 1242275302     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2004.05749.x     Document Type: Article

References (24)

1. Goodman GJ. Acne and acne scarring: why should we treat? Med J Aust 1999; 171: 62-3.
2. Layton AM, Henderson CA, Cunliffe WJ. A clinical evaluation of acne scarring and its incidence. Clin Exp Dermatol 1994; 19: 303-8.
3. Goodman GJ. Postacne scarring: a review of its pathophysiology and treatments. Dermatol Surg 2000; 26: 857-71.
4. Holland DB, Ingham E, Gowland G, Cunliffe WJ. IgG subclasses in acne vulgaris. Br J Dermatol 1986; 114: 349-51.
5. Ashbee HR, Muir SR, Cunliffe WJ, Ingham E. IgG subclasses specific to Staphylococcus epidermidis and Propionibacterium acnes in patients with acne vulgaris. Br J Dermatol 1997; 136: 730-3.
6. Puhvel SM, Amirian D, Weintaub J, Reisner RM. Lymphocyte transformation in subjects with nodulocystic acne. Br J Dermatol 1977; 97: 205-10.
7. Gowland G, Ward RM, Holland KT, Cunliffe WJ. Cellular immunity to P. acnes in the normal population and patients with acne vulgaris. Br J Dermatol 1978; 99: 43-7.
8. Kersey P, Sussman M, Dahl M. Delayed skin test reactivity to Propionibacterium acnes correlates with the severity of inflammation in acne vulgaris. Br J Dermatol 1980; 103: 651-5.
9. Kim J, Ochoa M-T, Krutzik SR et al. Activation of Toll-like receptor 2 in acne triggers inflammatory cytokine responses. J Immunol 2002; 169: 1535-41.
10. Norris JFB, Cunliffe WJ. A histological and immunocytochemical study of early acne lesions. Br J Dermatol 1988; 118: 651-9.
11. Layton AM, Morris C, Cunliffe WJ, Ingham E. Immunohistochemical investigation of evolving inflammation in lesions of acne vulgaris. Exp Dermatol 1998; 7: 191-7.
12. Jappe U, Ingham E, Henwood J, Holland KT. Propionibacterium acnes and inflammation in acne; P. acnes has T-cell mitogenic activity. Br J Dermatol 2002; 146: 202-9.
13. Holland DB, Morrison JFJ, Cunliffe WJ. Oligoclonality in T cell receptor Vβ gene usage in acne lesions. J Invest Dermatol 1995; 105: 482 (Abstract).
14. Burke BM, Cunliffe WJ. The assessment of acne vulgaris: the Leeds technique. Br J Dermatol 1984: 111: 83-92.
15. Cella C, Engering A, Pinet V et al. Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature 1997; 388: 782-7.
16. Nickoloff BJ, Wrone-Smith T. Injection of pre-psoriatic skin with CD4+ T cells induces psoriasis. Am J Pathol 1999; 155: 145-58.
17. Cameron AL, Kirby B, Fei W, Griffiths CE. Natural killer and natural killer-T cells in psoriasis. Arch Dermatol Res 2002; 294: 363-9.
18. Cunliffe WJ. Acne (Marks R, ed). London: Martin Dunitz, 1989: 4-6.
19. Bataille V, Snieder H, MacGregor AJ et al. The influence of genetics and environmental factors in the pathogenesis of acne: a twin study of acne in women. J Invest Dermatol 2002; 119: 1317-22.
20. Cowin AJ, Brosman MP, Holmes TM, Ferguson MWJ. Endogenous inflammatory response to dermal wound healing in the fetal and adult mouse. Dev Dynamics 1998; 212: 385-93.
21. Ashcroft GS, Horan MA, Ferguson MWJ. Aging is associated with reduced deposition of specific extracellular matrix components, an upregulation of angiogenesis, and an altered inflammatory response in a murine incisional wound healing model. J Invest Dermatol 1997; 108: 430-7.
22. Duncan MR, Berman B. Stimulation of collagen and glycosaminoglycan production in cultured human adult dermal fibroblasts by recombinant human interleukin 6. J Invest Dermatol 1991; 97: 686-92.
23. Appleton I, Tomlinson A, Colville-Nash PR, Willoughby DA. Temporal and spatial immunolocalisation of cytokines in murine chronic granulomatous tissue. Implications for their role in tissue development and repair processes. Lab Invest 1993; 69: 405-14.
24. Song E, Ouyang N, Horbelt M et al. Influence of alternatively and classically activated macrophages on fibrogenic activities of human fibroblasts. Cell Immunol 2000; 204: 19-28.