Serotonin-related FEV gene variant in the sudden infant death syndrome is a common polymorphism in the African-American population

Pediatric Research

Volumn 66, Issue 6, 2009, Pages 631-635

  Broadbelt, Kevin G ^a   Barger, Melissa A ^b   Paterson, David S ^a   Holm, Ingrid A ^b,c   Haas, Elisabeth A ^a   Krous, Henry F ^a   Kinney, Hannah C ^a   Markianos, Kyriacos ^b   Beggs, Alan H ^b,c,d  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b Program in Genomics   (United States)

^c Manton Center for Orphan Disease Research   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; SEROTONIN;

AFRICAN AMERICAN; ARTICLE; AUTOPSY; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SUDDEN INFANT DEATH SYNDROME;

AFRICAN AMERICANS; DNA PRIMERS; DNA-BINDING PROTEINS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; INDEL MUTATION; INFANT; INTRONS; MALE; MEDULLA OBLONGATA; NEURONS; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; SEROTONIN; SUDDEN INFANT DEATH;

EID: 73449130508     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1203/PDR.0b013e3181bd5a31     Document Type: Article

References (36)

1. Mathews TJ, MacDorman MF 2006 Infant mortality statistics from the 2003 period linked birth/infant death data set. Natl Vital Stat Rep 54:1-29
2. Krous HF, Beckwith JB, Byard RW, Rognum TO, Bajanowski T, Corey T, Cutz E, Hanzlick R, Keens TG, Mitchell EA 2004 Sudden infant death syndrome and unclassified sudden infant deaths: a definitional and diagnostic approach. Pediatrics 114:234-238
3. Filiano JJ, Kinney HC 1994 A perspective on neuropathologic findings in victims of the sudden infant death syndrome: the triple-risk model. Biol Neonate 65:194-197
4. Engelberts AC, de Jonge GA 1990 Choice of sleeping position for infants: possible association with cot death. Arch Dis Child 65:462-467
5. Fleming PJ, Gilbert R, Azaz Y, Berry PJ, Rudd PT, Stewart A, Hall E 1990 Interaction between bedding and sleeping position in the sudden infant death syndrome: a population based case-control study. BMJ 301:85-89
6. Willinger M, Hoffman HJ, Hartford RB 1994 Infant sleep position and risk for sudden infant death syndrome: report of meeting held January 13 and 14, 1994, National Institutes of Health, Bethesda, MD. Pediatrics 93:814-819
7. Hunt CE 2001 Sudden infant death syndrome and other causes of infant mortality: diagnosis, mechanisms, and risk for recurrence in siblings. Am J Respir Crit Care Med 164:346-357
8. Hunt CE, Hauck FR 2006 Sudden infant death syndrome. CMAJ 174:1861-1869
9. Iyasu S, Randall LL, Welty TK, Hsia J, Kinney HC, Mandell F, McClain M, Randall B, Habbe D, Wilson H, Willinger M 2002 Risk factors for sudden infant death syndrome among northern plains Indians. JAMA 288:2717-2723
10. Mitchell EA, Milerad J 2006 Smoking and the sudden infant death syndrome. Rev Environ Health 21:81-103
11. Vege A, Ole Rognum T 2004 Sudden infant death syndrome, infection and inflammatory responses. FEMS Immunol Med Microbiol 42:3-10
12. Oyen N, Skjaerven R, Irgens LM 1996 Population-based recurrence risk of sudden infant death syndrome compared with other infant and fetal deaths. Am J Epidemiol 144:300-305
13. Moon RY, Horne RS, Hauck FR 2007 Sudden infant death syndrome. Lancet 370:1578-1587
14. Cheng L, Chen CL, Luo P, Tan M, Qiu M, Johnson R, Ma Q 2003 Lmx1b, Pet-1, and Nkx2.2 coordinately specify serotonergic neurotransmitter phenotype. J Neuro-sci 23:9961-9967
15. Craven SE, Lim KC, Ye W, Engel JD, de Sauvage F, Rosenthal A 2004 Gata2 specifies serotonergic neurons downstream of sonic hedgehog. Development 131:1165-1173
16. Ding YQ, Marklund U, Yuan W, Yin J, Wegman L, Ericson J, Deneris E, Johnson RL, Chen ZF 2003 Lmx1b is essential for the development of serotonergic neurons. Nat Neurosci 6:933-938
17. Hendricks TJ, Fyodorov DV, Wegman LJ, Lelutiu NB, Pehek EA, Yamamoto B, Silver J, Weeber EJ, Sweatt JD, Deneris ES 2003 Pet-1 ETS gene plays a critical role in 5-HT neuron development and is required for normal anxiety-like and aggressive behavior. Neuron 37:233-247
18. Scott MM, Krueger KC, Deneris ES 2005 A differentially autoregulated Pet-1 enhancer region is a critical target of the transcriptional cascade that governs serotonin neuron development. J Neurosci 25:2628-2636
19. Scott MM, Wylie CJ, Lerch JK, Murphy R, Lobur K, Herlitze S, Jiang W, Conlon RA, Strowbridge BW, Deneris ES 2005 A genetic approach to access serotonin neurons for in vivo and in vitro studies. Proc Natl Acad Sci USA 102:16472-16477
20. Maurer P, Rorive S, de Kerchove d'Exaerde A, Schiffmann SN, Salmon I, de Launoit Y 2004 The Ets transcription factor FEV is specifically expressed in the human central serotonergic neurons. Neurosci Lett 357:215-218
21. Pfaar H, von Holst A, Vogt Weisenhorn DM, Brodski C, Guimera J, Wurst W 2002 mPet-1, a mouse ETS-domain transcription factor, is expressed in central serotoner-gic neurons. Dev Genes Evol 212:43-46
22. Rand CM, Berry-Kravis EM, Zhou L, Fan W, Weese-Mayer DE 2007 Sudden infant death syndrome: rare mutation in the serotonin system FEV gene. Pediatr Res 62:180-182
23. Kinney HC, Filiano JJ, White WF 2001 Medullary serotonergic network deficiency in the sudden infant death syndrome: review of a 15-year study of a single dataset. J Neuropathol Exp Neurol 60:228-247
24. Kinney HC, Myers MM, Belliveau RA, Randall LL, Trachtenberg FL, Fingers ST, Youngman M, Habbe D, Fifer WP 2005 Subtle autonomic and respiratory dysfunction in sudden infant death syndrome associated with serotonergic brainstem abnormalities: a case report. J Neuropathol Exp Neurol 64:689-694
25. Panigrahy A, Filiano J, Sleeper LA, Mandell F, Valdes-Dapena M, Krous HF, Rava LA, Foley E, White WF, Kinney HC 2000 Decreased serotonergic receptor binding in rhombic lip-derived regions of the medulla oblongata in the sudden infant death syndrome. J Neuropathol Exp Neurol 59:377-384
26. Paterson DS, Trachtenberg FL, Thompson EG, Belliveau RA, Beggs AH, Darnall R, Chadwick AE, Krous HF, Kinney HC 2006 Multiple serotonergic brainstem abnormalities in sudden infant death syndrome. JAMA 296:2124-2132
27. Kinney HC, Belliveau RA, Trachtenberg FL, Rava LA, Paterson DS 2007 The development of the medullary serotonergic system in early human life. Auton Neurosci 132:81-102
28. Machaalani R, Say M, Waters KA 2009 Serotoninergic receptor 1A in the sudden infant death syndrome brainstem medulla and associations with clinical risk factors. Acta Neuropathol 117:257-265
29. Ozawa Y, Okado N 2002 Alteration of serotonergic receptors in the brain stems of human patients with respiratory disorders. Neuropediatrics 33:142-149
30. Ozawa Y, Takashima S 2002 Developmental neurotransmitter pathology in the brainstem of sudden infant death syndrome: a review and sleep position. Forensic Sci Int 130:S53-S59
31. den Dunnen JT, Antonarakis SE 2000 Mutation nomenclature extensions and suggestions to describe complex mutations: a discussion. Hum Mutat 15:7-12
32. Wigginton JE, Cutler DJ, Abecasis GR 2005 A note on exact tests of Hardy-Weinberg equilibrium. Am J Hum Genet 76:887-893
33. Schoendorf KC, Hogue CJ, Kleinman JC, Rowley D 1992 Mortality among infants of black as compared with white college-educated parents. N Engl J Med 326:1522-1526
34. Price AL, Patterson N, Hancks DC, Myers S, Reich D, Cheung VG, Spielman RS 2008 Effects of cis and trans genetic ancestry on gene expression in African Americans. PLoS Genet 4:e1000294
35. Willinger M, James LS, Catz C 1991 Defining the sudden infant death syndrome (SIDS): deliberations of an expert panel convened by the National Institute of Child Health and Human Development. Pediatr Pathol 11:677-684
36. Krueger KC, Deneris ES 2008 Serotonergic transcription of human FEV reveals direct GATA factor interactions and fate of Pet-1-deficient serotonin neuron precursors. J Neurosci 28:12748-12758