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Volumn 16, Issue 3, 2009, Pages 13-21

Influence of CYP2D6 polymorphisms on symptomatology and side-effects of patients with schizophrenia in Malaysia

Author keywords

Cytochrome P450 CYP2D6; Neurosciences; Schizophrenia; Treatment outcomes

Indexed keywords

CHLORPROMAZINE; CLOZAPINE; CYTOCHROME P450 2D6; FLUPENTIXOL; FLUPHENAZINE; HALOPERIDOL; NEUROLEPTIC AGENT; OLANZAPINE; PERPHENAZINE; QUETIAPINE; RISPERIDONE; SULPIRIDE; TRIFLUOPERAZINE; TRIHEXYPHENIDYL; ZUCLOPENTHIXOL;

EID: 73449115327     PISSN: 1394195X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (7)

References (29)
  • 3
    • 0032704664 scopus 로고    scopus 로고
    • Pharmacologic treatment of schizophrenia
    • Kane JM. Pharmacologic treatment of schizophrenia. Biol Psychiatry 1999; 46:1396-1408.
    • (1999) Biol Psychiatry , vol.46 , pp. 1396-1408
    • Kane, J.M.1
  • 4
    • 33749478205 scopus 로고    scopus 로고
    • Genetics and the future of clinical psychiatry
    • Hariri AR, Lewis DA. Genetics and the future of clinical psychiatry. Am J Psychiatry. 2006;163:1676-1678.
    • (2006) Am J Psychiatry , vol.163 , pp. 1676-1678
    • Hariri, A.R.1    Lewis, D.A.2
  • 7
    • 0035049437 scopus 로고    scopus 로고
    • Cellular localization and regional distribution of CYP2D6 mRNA and protein expression in human brain
    • Siegle I, Fritz P, Eckhardt K, Zanger UM, Eichelbaum M. Cellular localization and regional distribution of CYP2D6 mRNA and protein expression in human brain. Pharmacogenetics. 2001; 11: 237-245.
    • (2001) Pharmacogenetics , vol.11 , pp. 237-245
    • Siegle, I.1    Fritz, P.2    Eckhardt, K.3    Zanger, U.M.4    Eichelbaum, M.5
  • 8
    • 33746102723 scopus 로고    scopus 로고
    • CYP2D6 genetic variation in healthy adults and psychiatric African-American subjects: Implications for clinical practice and genetic testing
    • Cai WM, Nikoloff DM, Pan RM, de Leon J, Fanti P, Fairchild M et al. CYP2D6 genetic variation in healthy adults and psychiatric African-American subjects: implications for clinical practice and genetic testing. Pharmacogenomics J. 2006; 6: 343-350.
    • (2006) Pharmacogenomics J , vol.6 , pp. 343-350
    • Cai, W.M.1    Nikoloff, D.M.2    Pan, R.M.3    de Leon, J.4    Fanti, P.5    Fairchild, M.6
  • 9
    • 0032793249 scopus 로고    scopus 로고
    • Polymorphic human cytochrome P450 enzymes: An opportunity for individualized drug treatment
    • Ingelman-Sundberg M, Oscarson M, McLellan RA. Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment. Trends Pharmacol Sci. 1999;20:342-349.
    • (1999) Trends Pharmacol Sci , vol.20 , pp. 342-349
    • Ingelman-Sundberg, M.1    Oscarson, M.2    McLellan, R.A.3
  • 10
    • 24944592412 scopus 로고    scopus 로고
    • Human CYP2D6 and mouse CYP2Ds: Organ distribution in a humanized mouse model
    • Miksys SL, Cheung C, Gonzalez FJ, Tyndale RF. Human CYP2D6 and mouse CYP2Ds: organ distribution in a humanized mouse model. Drug Metab Dispos 2005; 33: 1495-1502.
    • (2005) Drug Metab Dispos , vol.33 , pp. 1495-1502
    • Miksys, S.L.1    Cheung, C.2    Gonzalez, F.J.3    Tyndale, R.F.4
  • 11
    • 33847031732 scopus 로고    scopus 로고
    • CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure
    • Sistonen J, Sajantila A, Lao O, Corander J, Barbujani G, Fuselli S. CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure. Pharmacogenet Genomics. 2007;17:93-101.
    • (2007) Pharmacogenet Genomics , vol.17 , pp. 93-101
    • Sistonen, J.1    Sajantila, A.2    Lao, O.3    Corander, J.4    Barbujani, G.5    Fuselli, S.6
  • 12
    • 0031023815 scopus 로고    scopus 로고
    • Pharmacogenetics: A laboratory tool for optimizing therapeutic efficiency
    • Linder MW, Prough RA, Valdes R Jr. Pharmacogenetics: a laboratory tool for optimizing therapeutic efficiency. Clin Chem 1997;43:254-266.
    • (1997) Clin Chem , vol.43 , pp. 254-266
    • Linder, M.W.1    Prough, R.A.2    Valdes Jr., R.3
  • 13
    • 0031038038 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 variants in a Caucasian population: Allele frequencies and phenotypic consequences
    • Sachse C, Brockmoller J, Bauer S, Roots I. Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences. Am J Hum Genet. 1997; 60:284-295.
    • (1997) Am J Hum Genet , vol.60 , pp. 284-295
    • Sachse, C.1    Brockmoller, J.2    Bauer, S.3    Roots, I.4
  • 14
    • 0742286803 scopus 로고    scopus 로고
    • Cytochrome P450 2D6: Overview and update on pharmacology, genetics, biochemistry
    • Zanger UM, Raimundo S, Eichelbaum M. Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry. Naunyn Schmiedebergs Arch Pharmacol. 2004;369:23-37.
    • (2004) Naunyn Schmiedebergs Arch Pharmacol , vol.369 , pp. 23-37
    • Zanger, U.M.1    Raimundo, S.2    Eichelbaum, M.3
  • 15
    • 33748787999 scopus 로고    scopus 로고
    • Pharmacogenetics, drugmetabolizing enzymes, and clinical practice
    • Gardiner SJ, Begg EJ. Pharmacogenetics, drugmetabolizing enzymes, and clinical practice. Pharmacol Rev. 2006;58:521-590.
    • (2006) Pharmacol Rev , vol.58 , pp. 521-590
    • Gardiner, S.J.1    Begg, E.J.2
  • 16
    • 0034790063 scopus 로고    scopus 로고
    • Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6
    • Zanger UM, Fischer J, Raimundo S, Stüven T, Evert BO, Schwab M et al. Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6. Pharmacogenetics 2001; 11:573-585.
    • (2001) Pharmacogenetics , vol.11 , pp. 573-585
    • Zanger, U.M.1    Fischer, J.2    Raimundo, S.3    Stüven, T.4    Evert, B.O.5    Schwab, M.6
  • 17
    • 0027136288 scopus 로고
    • Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine
    • Johansson I, Lundqvist E, Bertilsson L, Dahl ML, Sjoqvist F, Ingelman-Sundberg M. Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine. Proc Natl Acad Sci USA. 1993;90:11825-11829.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11825-11829
    • Johansson, I.1    Lundqvist, E.2    Bertilsson, L.3    Dahl, M.L.4    Sjoqvist, F.5    Ingelman-Sundberg, M.6
  • 18
    • 0036204756 scopus 로고    scopus 로고
    • Molecular genetics of CYP2D6: Clinical relevance with focus on psychotropic drugs
    • Bertilsson L, Dahl ML, Dalen P, Al-Shurbaji A. Molecular genetics of CYP2D6: clinical relevance with focus on psychotropic drugs. Br J Clin Pharmacol 2002;53:111-122.
    • (2002) Br J Clin Pharmacol , vol.53 , pp. 111-122
    • Bertilsson, L.1    Dahl, M.L.2    Dalen, P.3    Al-Shurbaji, A.4
  • 19
    • 0035987391 scopus 로고    scopus 로고
    • Maintenance therapy with zuclopenthixol decanoate: Associations between plasma concentrations, neurological side effects and CYP2D6 genotype
    • Jaanson P, Marandi T, Kiivet RA, Vasar V, Vään S, Svensson JO et al. Maintenance therapy with zuclopenthixol decanoate: associations between plasma concentrations, neurological side effects and CYP2D6 genotype. Psychopharmacology (Berl). 2002;162:67-73.
    • (2002) Psychopharmacology (Berl) , vol.162 , pp. 67-73
    • Jaanson, P.1    Marandi, T.2    Kiivet, R.A.3    Vasar, V.4    Vään, S.5    Svensson, J.O.6
  • 20
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988; 16: 1215.
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 23
    • 34547697228 scopus 로고    scopus 로고
    • Depot haloperidol treatment in outpatients with schizophrenia on monotherapy: Impact of CYP2D6 polymorphism on pharmacokinetics and treatment outcome
    • Panagiotidis G, Arthur HW, Lindh JD, Dahl ML, Sjöqvist F. Depot haloperidol treatment in outpatients with schizophrenia on monotherapy: impact of CYP2D6 polymorphism on pharmacokinetics and treatment outcome. Ther Drug Monit. 2007;29:417-422.
    • (2007) Ther Drug Monit , vol.29 , pp. 417-422
    • Panagiotidis, G.1    Arthur, H.W.2    Lindh, J.D.3    Dahl, M.L.4    Sjöqvist, F.5
  • 24
    • 33750344176 scopus 로고    scopus 로고
    • The influence of the CYP2D6 polymorphism on psychopathological and extrapyramidal symptoms in the patients on long-term antipsychotic treatment
    • Plesničar BK, Zalar B, Breskvar K, Dolžan V. The influence of the CYP2D6 polymorphism on psychopathological and extrapyramidal symptoms in the patients on long-term antipsychotic treatment. J Psychopharmacol. 2006;20:829-833.
    • (2006) J Psychopharmacol , vol.20 , pp. 829-833
    • Plesničar, B.K.1    Zalar, B.2    Breskvar, K.3    Dolžan, V.4
  • 25
    • 0032725182 scopus 로고    scopus 로고
    • Genetic association analysis between CYP2D6*2 allele and tardive dyskinesia in schizophrenic patients
    • Ohmori O, Kojima H, Shinkai T, Terao T, Suzuki T, Abe K. Genetic association analysis between CYP2D6*2 allele and tardive dyskinesia in schizophrenic patients. Psychiatry Res. 1999; 87:239-244.
    • (1999) Psychiatry Res , vol.87 , pp. 239-244
    • Ohmori, O.1    Kojima, H.2    Shinkai, T.3    Terao, T.4    Suzuki, T.5    Abe, K.6
  • 26
    • 16844384063 scopus 로고    scopus 로고
    • Genetic susceptibility to tardive dyskinesia in chronic schizophrenia subjects: III. Lack of association of CYP3A4 and CYP2D6 gene polymorphisms
    • Tiwari AK, Deshpande SN, Rao AR, Bhatia T, Lerer B, Nimgaonkar VL et al. Genetic susceptibility to tardive dyskinesia in chronic schizophrenia subjects: III. Lack of association of CYP3A4 and CYP2D6 gene polymorphisms. Schizophr Res. 2005;75:21-26.
    • (2005) Schizophr Res , vol.75 , pp. 21-26
    • Tiwari, A.K.1    Deshpande, S.N.2    Rao, A.R.3    Bhatia, T.4    Lerer, B.5    Nimgaonkar, V.L.6
  • 27
    • 0029049844 scopus 로고
    • Polymorphic drug metabolism in schizophrenic patients with tardive dyskinesia
    • Arthur H, Dahl ML, Siwers B, Sjoqvist F. Polymorphic drug metabolism in schizophrenic patients with tardive dyskinesia. J Clin Psychopharmacol. 1995;15:211-216.
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 211-216
    • Arthur, H.1    Dahl, M.L.2    Siwers, B.3    Sjoqvist, F.4
  • 28
    • 0034467571 scopus 로고    scopus 로고
    • CYP2D6 genotype and antipsychotic-induced extrapyramidal side effects in schizophrenic patients
    • Scordo MG, Spina E, Romeo P, Dahl ML, Bertilsson L, Johansson I et al. CYP2D6 genotype and antipsychotic-induced extrapyramidal side effects in schizophrenic patients. Eur J Clin Pharmacol. 2000;56: 679-683.
    • (2000) Eur J Clin Pharmacol , vol.56 , pp. 679-683
    • Scordo, M.G.1    Spina, E.2    Romeo, P.3    Dahl, M.L.4    Bertilsson, L.5    Johansson, I.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.