Pharmacodynamic interaction between mefloquine and retinol in Plasmodium falciparum in vitro

Wiener Klinische Wochenschrift

Volumn 121, Issue SUPPL. 3, 2009, Pages 27-31

  Gruber, Maria ^a   Wernsdorfer, Gunther ^b   Satimai, Wichai ^c   Wiedermann, Ursula ^a   Congpuong, Kanungnit ^c   Wernsdorfer, Walther H ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b MAHIDOL UNIVERSITY   (Thailand)

^c MINISTRY OF PUBLIC HEALTH   (Thailand)

Author keywords

Mefloquine; Plasmodium falciparum; Retinol; Synergism; Thailand

Indexed keywords

4 AMINOQUINOLINE; MEFLOQUINE; METHANOL DERIVATIVE; QUININE; RETINOL;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG POTENTIATION; FEMALE; HUMAN; IC 50; IN VITRO STUDY; MALE; NONHUMAN; PLASMODIUM FALCIPARUM; SCHOOL CHILD; THAILAND;

ANTIMALARIALS; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; HUMANS; LETHAL DOSE 50; MEFLOQUINE; PLASMODIUM FALCIPARUM; VITAMIN A;

EID: 73449111932     PISSN: 00435325     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00508-009-1231-6     Document Type: Article

References (23)

1. EF Boudreau HK Webster K Pavanand L Thosingha 1982 Type II mefloquine resistance in Thailand Lancet 2 1335 10.1016/S0140-6736(82)91532-X 1:STN:280:DyaL3s%2FmtFGgtA%3D%3D 6128616
2. WH Wernsdorfer D Payne 1991 The dynamics of drug resistance in Plasmodium falciparum Pharmac Ther 50 95 121 10.1016/0163-7258(91)90074-V 1:CAS:528:DyaK3MXmsFWluro%3D
3. RN Price F Nosten C Luxemburger 1997 Artesunate/mefloquine treatment of multi-drug resistant falciparum malaria Trans R Soc Trop Med Hyg 91 574 577 10.1016/S0035-9203(97)90032-8 1:STN:280:DyaK1c7isVygsQ%3D%3D 9463672 (Pubitemid 27478651)
4. Gruber M (2009) Synergism between mefloquine and retinol in Plasmodium falciparum. Thesis, Medical University of Vienna
5. H Noedl Y Se K Schaecher BL Smith D Socheat MM Fukuda 2008 Evidence of artemisinin-resistant malaria in western Cambodia N Engl J Med 359 2619 2620 10.1056/NEJMc0805011 1:CAS:528:DC%2BD1cXhsV2ms7rM 19064625
6. P Lim AP Alker N Khim, et al. 2009 Pfmdr1 copy number and artemisinin derivatives combination therapy failure in falciparum malaria in Cambodia Malar J 8 11 10.1186/1475-2875-8-11 19138391 (PMID 19138391)
7. WO Rogers R Sem T Tero, et al. 2009 Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria in southern Cambodia Malar J 8 10 10.1186/1475-2875-8-10 19138388 (PMID 19138388)
8. A Metzger G Mukasa AH Shankar G Ndeezi G Melikiam RD Semba 2001 Antioxidant status and acute malaria in children in Kampala, Uganda Am J Trop Med Hyg 65 115 119 1:CAS:528:DC%2BD3MXmsV2ks7g%3D 11508384
9. DI Thurnham R Singkamani 1991 The acute phase response and vitamin A status in malaria Trans R Soc Trop Med Hyg 85 194 199 10.1016/0035-9203(91) 90017-S 1:CAS:528:DyaK3MXmtVCkuro%3D 1909468
10. TM Davis TQ Binh PT Danh IR Dyer A St John O Garcia-Webb, et al. 1004 Serum vitamin A and E concentrations in acute falciparum malaria; modulators or markers of severity? Clin Sci (Lond) 87 505 511
11. BS Das DI Thurnham DB Das 1996 Plasma alphatocopherol, retinol and carotenoids in children with falciparum malaria Am J Clin Nutr 64 94 100 1:STN:280:DyaK283ot1GjtA%3D%3D 8669421
12. JL Hautvast JJ Tolboom EC West EM Kafwembe RM Sauerwein WA van Staveren 1998 Malaria is associated with reduced serum retinol levels in rural Zambian children Int J Vitam Nutr Res 68 384 388 1:CAS:528:DyaK1cXnvVKnt7g%3D 9857266
13. V Nussenblatt G Mukasa A Metzger G Ndeezi W Eisinger RD Semba 2002 Relationship between carotenoids and anaemia during acute uncomplicated Plasmodium falciparum malaria in children J Health Popul Nutr 20 205 214 12430756
14. L Varandas M Julien A Gomes, et al. 2001 A randomised, double-blind, placebo-controlled clinical trial of vitamin A in severe malaria in hospitalised Mozambican children Ann Trop Paediatr 21 211 222 10.1080/02724930120077781 1:STN:280:DC%2BD3MrjtlWksA%3D%3D 11579859 (Pubitemid 32895551)
15. AH Shankar B Genton RD Semba M Baisor J Paino S Tamja, et al. 1999 Effect of vitamin A supplementation on morbidity due to Plasmodium falciparum in young children in Papua New Guinea: a randomised trial Lancet 354 9174 203 209 10.1016/S0140-6736(98)08293-2 1:CAS:528:DyaK1MXltVWhtLw%3D 10421302 (Pubitemid 29329159)
16. A Knauer K Congpuong G Wernsdorfer FF Reinthaler J Sirichaisinthop WH Wernsdorfer 2008 Synergism between quinine and retinol in fresh isolates of Plasmodium falciparum Wien Klin Wochenschr 120 Suppl 4 69 73 10.1007/s00508-008-1078-2 1:CAS:528:DC%2BD1MXmt1Knug%3D%3D 19066777
17. World Health Organization (1990) In vitro micro-test (Mark II) for the assessment of the response of Plasmodium falciparum to chloroquine, mefloquine, quinine, sulfadoxine/pyrimethamine and amodiaquine. WHO Document MAP/87.2, Revision 1, June 1990. WHO, Geneva
18. World Health Organization (1991) Basic malaria microscopy. Part I. WHO, Geneva
19. JT Litchfield F Wilcoxon 1949 A simplified method of evaluating dose-effect experiments J Pharmacol Exp Therapy 96 99 113 1:CAS:528: DyaH1MXjvFWmsA%3D%3D
20. WH Wernsdorfer MG Wernsdorfer 1995 The evaluation of in vitro tests for the assessment of drug response in Plasmodium falciparum Mitteilungen der Österreichischen Gesellschaft für Tropenmedizin und Parasitologie 17 221 228
21. MC Berenbaum 1978 A method for testing for synergy with any number of agents J Infect Diseases 137 122 130 1:CAS:528:DyaE1cXhvVahu7c%3D
22. C Rojanawatsirivet K Congpuong S Vijaykadga, et al. 2004 Declining mefloquine sensitivity of Plasmodium falciparum along the Thai-Myanmar border Southeast Asian J Trop Med Public Health 35 560 565 1:CAS:528:DC%2BD2cXhtFaktbfO 15689066
23. K Thriemer G Wernsdorfer C Rojanawatsirivet H Kollaritsch J Sirichaisinthop WH Wernsdorfer 2005 In vitro activity of artemisinin alone and in combination with retinol against Plasmodium falciparum Wien Klin Wochenschr 117 Suppl 4 45 48 10.1007/s00508-005-0447-3 1:CAS:528:DC%2BD28Xms1WrsA%3D%3D 16416385