Beyond the antioxidant properties: Pomegranate juice polyphenols increase hepatocyte paraoxonase 1 secretion

Atherosclerosis

Volumn 208, Issue 1, 2010, Pages 28-29

  Gugliucci, Alejandro ^a  

^a TOURO UNIVERSITY CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARYLDIALKYLPHOSPHATASE 1; ELAGITANNIN; ESTERASE; GLUCONOLACTONASE; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; POLYPHENOL; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL TRANSPORT; ENZYME ACTIVITY; ENZYME RELEASE; GENETIC TRANSCRIPTION; HUMAN; LIVER CELL; NONHUMAN; POMEGRANATE JUICE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 73449098890     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2009.09.032     Document Type: Note

References (6)

1. Soran H., Younis N.N., Charlton-Menys V., and Durrington P. Variation in paraoxonase-1 activity and atherosclerosis. Curr Opin Lipidol 20 (2009) 265-274
2. Seo D., and Goldschmidt-Clermont P. The paraoxonase gene family and atherosclerosis. Curr Atheroscler Rep 11 (2009) 182-187
3. Khateeb J., Gantman A., Kreitenberg A.J., Aviram M., Fuhrman B., et al. Paraoxonase 1 (PON1) expression in hepatocytes is upregulated by pomegranate polyphenols: a role for PPAR-γ pathway. Atherosclerosis 208 (2010) 119-125
4. Aviram M., Kaplan M., Rosenblat M., and Fuhrman B. Dietary antioxidants and paraoxonases against LDL oxidation and atherosclerosis development. Handb Exp Pharmacol (2005) 263-300
5. Shiner M., Fuhrman B., and Aviram M. Macrophage paraoxonase 2 (PON2) expression is up-regulated by pomegranate juice phenolic anti-oxidants via PPAR gamma and AP-1 pathway activation. Atherosclerosis 195 (2007) 313-321
6. Gong M., Garige M., Varatharajalu R., et al. Quercetin up-regulates paraoxonase 1 gene expression with concomitant protection against LDL oxidation. Biochem Biophys Res Commun 379 (2009) 1001-1004