Extraribosomal function of metallopanstimulin-1: Reducing paxillin in head and neck squamous cell carcinoma and inhibiting tumor growth

International Journal of Cancer

Volumn 126, Issue 3, 2010, Pages 611-619

  Dai, Yuemeng ^a   Pierson, Spencer E ^a   Dudney, W Cross ^a   Stack Jr , Brendan C ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Head and neck squamous cell carcinoma; Metallopanstimulin 1; Paxillin; RPS27

Indexed keywords

MESSENGER RNA; METALLOPANSTIMULIN 1; PAXILLIN; RIBOSOME PROTEIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL FUNCTION; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; CYTOSOL; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC TRANSFECTION; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RIBOSOME; STAINING; TUMOR GROWTH; WESTERN BLOTTING;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; CELL LINE, TUMOR; CULTURE MEDIA, CONDITIONED; G0 PHASE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAD AND NECK NEOPLASMS; HUMANS; MALE; METALLOPROTEINS; MICE; MICE, NUDE; NEOPLASM PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; NUCLEAR PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PAXILLIN; RECOMBINANT FUSION PROTEINS; RIBOSOMAL PROTEINS; RNA, MESSENGER; RNA, NEOPLASM; RNA-BINDING PROTEINS; TRANSFECTION;

EID: 73449094226     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24791     Document Type: Article

References (34)

1. Fatica A, Tollervey D. Making ribosomes. Curr Opin Cell Biol 2002;14:313-8.
2. Wilson DM, Deutsch WA, Kelley MR. Drosophila ribosomal protein S3 contains an activity that cleaves DNA at apurinic/ apyrimidinic sites. J Biol Chem 1994;269:25359-64.
3. Sandigursky M, Yacoub A, Kelley MR, Deutsch WA, Franklin WA. The Drosophila ribosomal protein S3 contains a DNA deoxyribophosphodiesterase (dRpase) activity. J Biol Chem 1997;272:17480-4.
4. Jang CY, Lee JY, Kim J. RpS3, a DNA repair endonuclease and ribosomal protein, is involved in apoptosis. FEBS Lett 2004;560:81-5.
5. Khanna N, Sen S, Sharma H, Singh N. S29 ribosomal protein induces apoptosis in H520 cells and sensitizes them to chemotherapy. Biochem Biophys Res Commun 2003;304:26-35.
6. He H, Sun Y. Ribosomal protein S27L is a direct p53 target that regulates apoptosis. Oncogene 2007;26:2707-16.
7. Shi Y, Zhai H, Wang X, Han Z, Liu C, Lan M, Du J, Guo C, Zhang Y, Wu K, Fan D. Ribosomal proteins S13 and L23 promote multidrug resistance in gastric cancer cells by suppressing drug-induced apoptosis. Exp Cell Res 2004;296:337-46.
8. Hamaguchi I, Ooka A, Brun A, Richter J, Dahl N, Karlsson S. Gene transfer improves erythroid development in ribosomal protein S19-deficient Diamond-Blackfan anemia. Blood 2002;100:2724-31.
9. Naora H, Takai I, Adachi M, Naora H. Altered cellular responses by varying expression of a ribosomal protein gene: sequential coordination of enhancement and suppression of ribosomal protein S3a gene expression induces apoptosis. J Cell Biol 1998;141:741-53.
10. Wong JM, Mafune K, Yow H, Rivers EN, Ravikumar TS, Steele GD Jr., Chen LB. Ubiquitin-ribosomal protein S27a gene overexpressed in human colorectal carcinoma is an early growth response gene. Cancer Res 1993;53:1916-20.
11. Kondoh N, Shuda M, Tanaka K, Wakatsuki T, Hada A, Yamamoto M. Enhanced expression of S8, L12, L23a, L27 and L30 ribosomal protein mRNAs in human hepatocellular carcinoma. Anticancer Res 2001;21(4A):2429-33.
12. Bee A, Ke Y, Forootan S, Lin K, Beesley C, Forrest SE, Foster CS. Ribosomal protein l19 is a prognostic marker for human prostate cancer. Clin Cancer Res 2006;12(Pt 1):2061-5.
13. Fernandez-Pol JA, Klos DJ, Hamilton PD. A growth factor-inducible gene encodes a novel nuclear protein with zinc finger structure. J Biol Chem 1993;268:21198-204.
14. Stack BC Jr., Dalsaso TA, Lee C Jr., Lowe VJ, Hamilton PD, Fletcher JW, Fernandez-Pol JA. Over-expression of MPS antigens by squamous cell carcinomas of the head and neck: immunohistochemical and serological correlation with FDG positron emission tomography. Anticancer Res 1999;19(6C):5503-10.
15. Stack BC Jr., Hollenbeak CS, Lee CM, Dunphy FR, Lowe VJ, Hamilton PD. Metallopanstimulin as a marker for head and neck cancer. World J Surg Oncol 2004;2:45-53.
16. Fernandez-Pol JA, Fletcher JW, Hamilton PD, Klos DJ. Expression of metallopanstimulin and oncogenesis in human prostatic carcinoma. Anticancer Res 1997;17(3A):1519-30.
17. Ganger DR, Hamilton PD, Fletcher JW, Fernandez-Pol JA. Metallopanstimulin is overexpressed in a patient with colonic carcinoma. Anticancer Res 1997;17(3C):1993-9.
18. Ganger DR, Hamilton PD, Klos DJ, Jakate S, McChesney L, Fernandez-Pol JA. Differential expression of metallopanstimulin/S27 ribosomal protein in hepatic regeneration and neoplasia. Cancer Detect Prev 2001;25:231-6.
19. Atsuta Y, Aoki N, Sato K, Oikawa K, Nochi H, Miyokawa N, Hirata S, Kimura S, Sasajima T, Katagiri M. Identification of metallopanstimulin-1 as a member of a tumor associated antigen in patients with breast cancer. Cancer Lett 2002;182:101-7.
20. Wang YW, Qu Y, Li JF, Chen XH, Liu BY, Gu QL, Zhu ZG. In vitro and in vivo evidence of metallopanstimulin-1 in gastric cancer progression and tumorigenicity. Clin Cancer Res 2006;12:4965-73.
21. Zhan F, Hardin J, Kordsmeier B, Bumm K, Zheng M, Tian E, Sanderson R, Yang Y, Wilson C, Zangari M, Anaissie E, Morris C, et al. Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells. Blood 2002;99:1745-57.
22. Fernandez-Pol JA, Klos DJ, Hamilton PD. Metallopanstimulin gene product produced in a baculovirus expression system is a nuclear phosphoprotein that binds to DNA. Cell Growth Differ 1994;5:811-25.
23. Fernandez-Pol JA, Hamilton PD, Klos DJ. Essential viral and cellular zinc and iron containing metalloproteins as targets for novel antiviral and anticancer agents: implications for prevention and therapy of viral diseases and cancer. Anticancer Res 2001;21(2A):931-57.
24. Folkman J. What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 1990;82:4-6.
25. Ruggero D, Pandolfi. Does the ribosome translate cancer? Nat Rev Cancer 2003;3:179-92. 26. Lee WJ, Keefer K, Hollenbeak CS, Stack BC Jr. A new assay to screen for head and neck squamous cell carcinoma using the tumor marker metallopanstimulin. Otolaryngol Head Neck Surg 2004;131:466-71.
26. Vermeulen K, Van Bockstaele DR, Berneman ZN. Apoptosis: mechanisms and relevance in cancer. Ann Hematol 2005;84:627-39.
27. Park MT, Lee SJ. Cell cycle and cancer. J Biochem Mol Biol 2003;36:60-5.
28. Kuerbitz SJ, Plunkett BS, Walsh WV, Kastan MB. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. PNAS 1992;89:7491-5.
29. Reed M, Woelker B, Wang P, Wang Y, Anderson ME, Tegtmeyer P. The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation. PNAS 1995;92:9455-9.
30. Schaller MD. Paxillin: a focal adhesion-associated adaptor protein. Oncogene 2001;20:6459-72.
31. Brown MC, Turner CE. Paxillin: adapting to change. Physiol Rev 2004;84:1315-39.
32. Jagadeeswaran R, Surawska H, Krishnaswamy S, Janamanchi V, Mackinnon AC, Seiwert TY, Loganathan S, Kanteti R, Reichman T, Nallasura V, Schwartz S, Faoro L, et al. Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion. Cancer Res 2008;68:132-42.
33. Tatsumi Y, Cho YY, He ZW, Mizuno H, Choi HS, Bode AM, Dong ZG. Involvement of the paxillin pathway in JB6 C141 cell transformation. Cancer Res 2006;66:5968-74.
34. Minamiguchi K, Kumagai H, Masuda T, Kawada M, Ishizuka M, Takeuchi T. Thiolutin, an inhibitor of HUVEC adhesion to vitronectin, reduces paxillin in HUNVCs and suppresses tumor cell-induced angiogenesis. Int J Cancer 2001;93:307-16.