Engraftment of human myelodysplastic syndrome derived cell line in transgenic severe combined immunodeficient (TG-SCID) mice expressing human GM-CSF and IL-3

European Journal of Haematology

Volumn 61, Issue 2, 1998, Pages 93-99

  Kim, Dong Ku ^a   Kojima, Masaharu ^a   Fukushima, Takashi ^a   Miyasaka, Masayuki ^b   Nakauchi, Hiromitsu ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

GM CSF; IL 3; Myelodysplastic syndrome; NK cells; SCID mice; Transgenic mice

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3;

ARTICLE; CELL PROLIFERATION; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE STRUCTURE; HUMAN; HUMAN CELL; MOUSE; MYELODYSPLASTIC SYNDROME; NATURAL KILLER CELL; NONHUMAN; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 7344250088     PISSN: 09024441     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0609.1998.tb01067.x     Document Type: Article

References (38)

1. BOSMA GC, CLUSTER RP, BOSMA MJ. A severe combined immunodeficiency mutation in the mouse. Nature 1983: 301: 527-530.
2. BOSMA MJ, CARROLL AM. The scid mouse mutant: definition, characterization, and potential uses. Annu Rev Immunol 1991: 9: 323-350.
3. MOSIER DE, GULIZIA RJ, BAIRD SM, WILSON DB. Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature 1988: 335: 256-259.
4. MCCUNE JM, NAMIKAWA R, KANESHIMA H, SHULTZ LD, LIEBERMAN M, WEISSMAN IL. The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. Science 1988: 241: 1632-1639.
5. MCCUNE J, KANESHIMA H, KROWKA J, et al. The SCID-hu mouse: a small animal model for HIV infection and pathogenesis. Annu Rev Immunol 1991: 9: 399-429.
6. KYOIZUMI S, BAUM CM, KANESHIMA H, MCCUNE JM, YEE EJ, NAMIKAWA R. Implantation and maintenance of functional human bone marrow in SCID-hu mice. Blood 1992: 79: 1704-1711.
7. SANDHU JS, CLARK BR, BOYNTON EL, et al. Human hematopoicsis in SCID mice implanted with human adult cancerous bone. Blood 1996: 88: 1973-1982.
8. LAPIDOT T, PFLUMIO F, DOEDENS M, MURDOCH B, WILLIAMS DE, DICK JE. Cytokine stimulation of multilineage hematopoicsis from immature human cells engrafted in SCID mice. Science 1992: 255: 1137-1141.
9. VORMOOR J, LAPIDOT T, PFLUMIO F, et al. Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice. Blood 1994: 83: 2489-2497.
10. CASHMAN JD, LAPIDOT T, WANG JC, et al. Kinetic evidence of the regeneration of multilineage hematopoicsis from primitive cells in normal human bone marrow transplanted into immunodeficient mice. Blood 1997: 89: 4307-4316.
11. GAN OI, MURDOCH B, LAROCHELLE A, DICK JE. Differential maintenance of primitive human SCID-repopulating cells, clonogenic progenitors and long-term culture-initiating cells after incubation on human bone marrow stromal cells. Blood 1997: 90: 641-650.
12. WANG JC, DOEDENS M, DICK JE. Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in viva SCID-repopulating cells assay. Blood 1997: 89: 3919-3924.
13. BOCK TA, ORLIC D, DUNBAR CE, BROXMEYER HE, BODINE DM. Improved engraftment of human hematopoietic cells in severe combined immunodeficient (SCID) mice carrying human cytokines transgenes. J Exp Med 1995: 182: 2037-2043.
14. LAPIDOT T, SIRARD C, VORMOOR J, et al. A cell initiating human acute myeloid leukemia after transplantation into SCID mice. Nature 1994: 367: 645-648.
15. SIRARD C, LAPIDOT T, VORMOOR J. et al. Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis. Blood 1996: 87: 1539-1548.
16. BONNET D, DICK JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nature Med 1997: 3: 730-737.
17. YANG YC, CIALETTA AB, TEMPLE PA, et al. Human IL-3(multi-CSF): identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3. Cell 1986: 47: 3-10.
18. GOUGH NM, GPIGJ J, METCALF D, et al. Molecular cloning of cDNA encoding a murine hematopoietic growth regulator, granulocyte-macrophage colony stimulating factor. Nature 1984: 309: 763-767.
19. NOLTA JA, HANLEY MB, KOHN DB. Sustained human hematopoiesis in immunodeficient mice by cotransplantation of marrow stroma expressing human interleukin-3: analysis of gene transduction of long-lived progenitor. Blood 1994: 83: 3041-3051.
20. LACERDA JF, LADANYI M, JAGIELLO C, O'REILLY RJ. Administration of rabbit anti-asialo GMI antiserum facilitates the development human Epstein-Barr virus-induced lymphoproliferations in xenografted C.B-17 scid/scid mice. Transplantation 1996: 61: 492-497.
21. KAMEL-REID S, DICK JE. Engraftment of immune-deficient mice with human hematopoietic stem cells. Science 1988: 242: 1706-1709.
22. HISHA H, NISHINO T, KAWAMURA M, ADACHI S, IKEHARA S. Successful bone marrow transplantation by bone grafts in chimeric resistant combination. Exp Hematol 1995: 23: 347-352.
23. MURPHY WJ, KUMAR V, BENNET M. Acute rejection of murine bone marrow allografts by natural killer cells and T cells. Differences in kinetics and target antigens recognized. J Exp Med 1987: 166: 1499-1509.
24. TANAKA T, TSUDO M, KARASUYAMA H, et al. A novel monoclonal antibody against murine IL-2 receptor β-chain: characterization of receptor expression in normal lymphoid cells and EL-4 cells. J Immunol 1991: 147: 2222-2228.
25. TANAKA T, KITAMURA F, NAGASAKA Y, KUIDA K, SUWA H, MIYASAKA M. Selective long-term elimination of natural killer cells in vivo by an anti-IL-2 receptor β chain monoclonal antibody in mice. J Exp Med 1993: 178: 1103-1107.
26. CHIBA S, TAKAKU F, TANGE T, et al. Establishment and erythroid differentiation of a cytokine-dependent human leukemic cell line F-36: a parental line requiring granulocyte-macrophage colony-stimulating factor of interleukin-3, and a subline requiring erythropoietin. Blood 1991: 78: 2261-2268.
27. HABU S, FUKUI H, SHIMAMURA K, et al. In vivo effects of anti-asialo GM1 I. Reduction of NK activity and enhancement of transplanted tumor growth in nude mice. J Immunol 1981: 127: 34-38.
28. BARRY TS, JONES DM, RICHTER CB, HAYNES BF. Successful engraftment of human postnatal thymus in severe combined immune deficient (SCID) mice: differential engraftment of thymic components with irradiation versus anti-asialo GM-1 immunosuppressive regimens. J Exp Med 1991: 173: 167-180.
29. SHPITZ B, FERNANDES BJ, MULLEN JB, RODER JC, GALLINGER S. Improved engraftment of human tumors in SCID mice pretreated with radiation and anti-asialo GM1. Anticancer Res 1994: 14: 1927-1934.
30. MURPHY WJ, FUNAKOSHI S, BECKWITH M, et al. Antibodies to CD40 prevent Epstein-Barr virus-mediated human B-cell lymphomagenesis in severe combined immune deficient mice given human peripheral blood lymphocyte. Blood 1995: 86: 1946-1953.
31. SANDHU JS, CLARK BR, BOYNTON EL, et al. Human hematopoiesis in SCID mice implanted with human adult cancellous bone. Blood 1996: 88: 1973-1982.
32. SHULTZ LD, SCHWEITZER PA, CHRISTIANSON SW, et al. Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice. J Immunol 1995: 154: 180-191.
33. PELUMIO F, IZAC B, KATZ A, SCHULTZ LD, VAINCHENKER W, COULOMBEL L. Phenotype and function of human hematopoietic cells engrafting immune deficient CB-17-severe combined immunodeficiency mice and nonobese diabetic-severe combined immunodeficiency mice after transplantation of human cord blood mononuclear cells. Blood 1996: 88: 3731-3740.
34. LAROCHELLE A, VORMOOR J, HANENBERG H, et al. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: implications for gene therapy. Nature Med 1996: 2: 1329-1337.
35. HUANG YW, RICHARDSON JA, TONG AW, ZHANG BQ, STONE MJ, VITETTA ES. Disseminated growth of a human multiple myeloma cell line in mice with severe combined immunodeficiency disease. Cancer Res 1993: 53: 1392-1396.
36. GUNTHER R, CHELSTROM LM, TUEL-AHLGREN L, SIMON J, MYERS DE, UCKUN FM. Biotherapy for xenografted human central nervous system leukemia in mice with severe combined immunodeficiency using B43 (Anti-CD19)-pokeweed antiviral protein immunotoxin. Blood 1995: 85: 2537-2545.
37. ALSINA M, BOYCE B, DEVLIN RD, et al. Development of an in vivo model of human multiple myeloma bone disease. Blood 1996: 87: 1495-1501.
38. BATAILLE R, CHAPPARD D, MARCELLI C, et al. Mechanism of bone destruction in multiple myeloma. The importance of an unbalanced process in determining the severity of lytic bone disease. J Clin Oncol 1989: 7: 1909-1914.