메뉴 건너뛰기




Volumn 29, Issue 12, 2009, Pages 1482-1490

Survival data of patients with anthracycline- or taxane-pretreated or resistant metastatic breast cancer

Author keywords

Anthracycline resistance; Metastatic breast cancer; Overall survival; Progression free survival; Taxane resistance

Indexed keywords

ANTHRACYCLINE; BEVACIZUMAB; CAPECITABINE; CYTOTOXIC AGENT; DOCETAXEL; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GEMCITABINE; IXABEPILONE; LAPATINIB; MITOMYCIN; NAVELBINE; PACLITAXEL; TAXANE DERIVATIVE; TRASTUZUMAB; VINBLASTINE;

EID: 73349139872     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1592/phco.29.12.1482     Document Type: Review
Times cited : (6)

References (35)
  • 1
    • 33747813779 scopus 로고    scopus 로고
    • Rockville, MD: U.S. Department of Health and Human Services, Center for Drug Evaluation and Research, Center for Biologics Evaluation and Research. May, Available from, Accessed October 2, 2009
    • . U.S. Food and Drug Administration. Guidance for industry: clinical trial endpoints for the approval of cancer drugs and biologics. Rockville, MD: U.S. Department of Health and Human Services, Center for Drug Evaluation and Research, Center for Biologics Evaluation and Research. May 2007. Available from http://www.fda.gov/downloads/Drugs/GuidanceComplianceR egulatoryInformation/Guidances/UCM071590.pdf. Accessed October 2, 2009.
    • (2007) Guidance for industry: Clinical trial endpoints for the approval of cancer drugs and biologics
  • 2
    • 0037674049 scopus 로고    scopus 로고
    • Overall survival is not a realistic end point for clinical trials of new drugs in advanced solid tumors: A critical assessment based on recently reported phase III trials in colorectal and breast cancer
    • . Di Leo A, Bleiberg H, Buyse M. Overall survival is not a realistic end point for clinical trials of new drugs in advanced solid tumors: a critical assessment based on recently reported phase III trials in colorectal and breast cancer. J Clin Oncol 2003;21:2045-7.
    • (2003) J Clin Oncol , vol.21 , pp. 2045-2047
    • Di Leo, A.1    Bleiberg, H.2    Buyse, M.3
  • 3
    • 55949094052 scopus 로고    scopus 로고
    • Relationship between effects on time-to-disease progression and overall survival in studies of metastatic breast cancer
    • . Sherrill B, Amonkar M, Wu Y, et al. Relationship between effects on time-to-disease progression and overall survival in studies of metastatic breast cancer. Br J Cancer 2008;99:1572-8.
    • (2008) Br J Cancer , vol.99 , pp. 1572-1578
    • Sherrill, B.1    Amonkar, M.2    Wu, Y.3
  • 4
    • 46949103546 scopus 로고    scopus 로고
    • Metastatic breast cancer: The treatment challenge
    • . Jones SE. Metastatic breast cancer: the treatment challenge. Clin Breast Cancer 2008;8:224-33.
    • (2008) Clin Breast Cancer , vol.8 , pp. 224-233
    • Jones, S.E.1
  • 5
    • 0037441856 scopus 로고    scopus 로고
    • Phase III trial of doxorubicin, paclitaxel, and the combination of doxorubicin and paclitaxel as front-line chemotherapy for metastatic breast cancer: An intergroup trial (E1193)
    • . Sledge GW, Neuberg D, Bernardo P, et al. Phase III trial of doxorubicin, paclitaxel, and the combination of doxorubicin and paclitaxel as front-line chemotherapy for metastatic breast cancer: an intergroup trial (E1193). J Clin Oncol 2003;21:588-92.
    • (2003) J Clin Oncol , vol.21 , pp. 588-592
    • Sledge, G.W.1    Neuberg, D.2    Bernardo, P.3
  • 6
    • 33751400314 scopus 로고    scopus 로고
    • Capecitabine (X) and taxanes in patients (pts) with anthracycline-pretreated metastatic breast cancer (MBC): Sequential vs combined therapy results from a MOSG randomized phase III trial [abstract]
    • abstract 570
    • . Soto C, Torrecillas L, Reyes S, et al. Capecitabine (X) and taxanes in patients (pts) with anthracycline-pretreated metastatic breast cancer (MBC): sequential vs combined therapy results from a MOSG randomized phase III trial [abstract]. J Clin Oncol 2006;24(suppl 18):abstract 570.
    • (2006) J Clin Oncol , vol.24 , Issue.SUPPL. 18
    • Soto, C.1    Torrecillas, L.2    Reyes, S.3
  • 7
    • 16844373011 scopus 로고    scopus 로고
    • Optimizing the treatment of metastatic breast cancer
    • . Gralow JR. Optimizing the treatment of metastatic breast cancer. Breast Cancer Res Treat 2005;89(suppl 1):S9-15.
    • (2005) Breast Cancer Res Treat , vol.89 , Issue.SUPPL. 1
    • Gralow, J.R.1
  • 8
    • 38449115081 scopus 로고    scopus 로고
    • Overview of resistance to systemic therapy in patients with breast cancer
    • . Gonzalez-Angulo A, Morales-Vasquez F, Hortobagyi G. Overview of resistance to systemic therapy in patients with breast cancer. Adv Exp Med Biol. 2007;608:1-22.
    • (2007) Adv Exp Med Biol , vol.608 , pp. 1-22
    • Gonzalez-Angulo, A.1    Morales-Vasquez, F.2    Hortobagyi, G.3
  • 9
    • 58149503624 scopus 로고    scopus 로고
    • Ixabepilone: Targeting βIII-tubulin expression in taxane-resistant malignancies
    • . Dumontet C, Jordan M, Lee F. Ixabepilone: targeting βIII-tubulin expression in taxane-resistant malignancies. Mol Cancer Ther 2009;8:17-25.
    • (2009) Mol Cancer Ther , vol.8 , pp. 17-25
    • Dumontet, C.1    Jordan, M.2    Lee, F.3
  • 10
    • 0035868906 scopus 로고    scopus 로고
    • Doxorubicin and paclitaxel versus fluorouracil, doxorubicin, and cyclophosphamide as first-line therapy for women with metastatic breast cancer: Final results of a randomized phase III multicenter trial
    • . Jassem J, Pienkowski T, Pluzanska A, et al. Doxorubicin and paclitaxel versus fluorouracil, doxorubicin, and cyclophosphamide as first-line therapy for women with metastatic breast cancer: final results of a randomized phase III multicenter trial. J Clin Oncol 2001;19:1707-15.
    • (2001) J Clin Oncol , vol.19 , pp. 1707-1715
    • Jassem, J.1    Pienkowski, T.2    Pluzanska, A.3
  • 11
    • 0037099533 scopus 로고    scopus 로고
    • Doxorubicin and paclitaxel versus doxorubicin and cyclophosphamide as firstline chemotherapy in metastatic breast cancer: The European organization for research and treatment of cancer 10961 multicenter phase III trial
    • . Biganzoli L, Cufer T, Bruning P, et al. Doxorubicin and paclitaxel versus doxorubicin and cyclophosphamide as firstline chemotherapy in metastatic breast cancer: the European organization for research and treatment of cancer 10961 multicenter phase III trial. J Clin Oncol 2002;20:3114-21.
    • (2002) J Clin Oncol , vol.20 , pp. 3114-3121
    • Biganzoli, L.1    Cufer, T.2    Bruning, P.3
  • 12
    • 0037445247 scopus 로고    scopus 로고
    • Docetaxel and doxorubicin compared with doxorubicin and cyclophosphamide as first-line chemotherapy for metastatic breast cancer: Results of a randomized, multicenter, phase III trial
    • for the TAX 306 Study Group
    • . Nabholtz JM, Falkson C, Campos D, et al, for the TAX 306 Study Group. Docetaxel and doxorubicin compared with doxorubicin and cyclophosphamide as first-line chemotherapy for metastatic breast cancer: results of a randomized, multicenter, phase III trial. J Clin Oncol 2003;21:968-75.
    • (2003) J Clin Oncol , vol.21 , pp. 968-975
    • Nabholtz, J.M.1    Falkson, C.2    Campos, D.3
  • 13
    • 27244438750 scopus 로고    scopus 로고
    • Phase II to III study comparing doxorubicin and docetaxel with fluorouracil, doxorubicin, and cyclophosphamide as first-line chemotherapy in patients with metastatic breast cancer: Results of a Dutch community setting trial for the clinical trial group of the comprehensive cancer centre
    • . Bontenbal M, Creemers GJ, Braun HJ, et al. Phase II to III study comparing doxorubicin and docetaxel with fluorouracil, doxorubicin, and cyclophosphamide as first-line chemotherapy in patients with metastatic breast cancer: results of a Dutch community setting trial for the clinical trial group of the comprehensive cancer centre. J Clin Oncol 2005;23:7081-8.
    • (2005) J Clin Oncol , vol.23 , pp. 7081-7088
    • Bontenbal, M.1    Creemers, G.J.2    Braun, H.J.3
  • 14
    • 33644680299 scopus 로고    scopus 로고
    • Phase III trial of epirubicin plus paclitaxel compared with epirubicin plus cyclophosphamide as first-line chemotherapy for metastatic breast cancer: United Kingdom national cancer research institute trial AB01
    • . Langley RE, Carmichael J, Jones AL, et al. Phase III trial of epirubicin plus paclitaxel compared with epirubicin plus cyclophosphamide as first-line chemotherapy for metastatic breast cancer: United Kingdom national cancer research institute trial AB01. J Clin Oncol 2005;23:8322-30.
    • (2005) J Clin Oncol , vol.23 , pp. 8322-8330
    • Langley, R.E.1    Carmichael, J.2    Jones, A.L.3
  • 15
    • 24944507764 scopus 로고    scopus 로고
    • Randomized phase III study of docetaxel compared with paclitaxel in metastatic breast cancer
    • . Jones SE, Erban J, Overmoyer B, et al. Randomized phase III study of docetaxel compared with paclitaxel in metastatic breast cancer. J Clin Oncol 2005;23:5542-51.
    • (2005) J Clin Oncol , vol.23 , pp. 5542-5551
    • Jones, S.E.1    Erban, J.2    Overmoyer, B.3
  • 16
    • 32944482677 scopus 로고    scopus 로고
    • Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer
    • . Gradishar WJ, Tjulandin S, Davidson N, et al. Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer. J Clin Oncol 2005;23:7794-803.
    • (2005) J Clin Oncol , vol.23 , pp. 7794-7803
    • Gradishar, W.J.1    Tjulandin, S.2    Davidson, N.3
  • 17
    • 50549096593 scopus 로고    scopus 로고
    • Gemcitabine plus paclitaxel versus paclitaxel monotherapy in patients with metastatic breast cancer and prior anthracycline treatment
    • . Albain KS, Nag SM, Calderillo-Ruiz G, et al. Gemcitabine plus paclitaxel versus paclitaxel monotherapy in patients with metastatic breast cancer and prior anthracycline treatment. J Clin Oncol 2008;26:3950-7.
    • (2008) J Clin Oncol , vol.26 , pp. 3950-3957
    • Albain, K.S.1    Nag, S.M.2    Calderillo-Ruiz, G.3
  • 18
    • 5444251223 scopus 로고    scopus 로고
    • Randomized phase III trial of pegylated liposomal doxorubicin versus vinorelbine or mitomycin C plus vinblastine in women with taxane-refractory advanced breast cancer
    • . Keller AM, Mennel RG, Georgoulias VA, et al. Randomized phase III trial of pegylated liposomal doxorubicin versus vinorelbine or mitomycin C plus vinblastine in women with taxane-refractory advanced breast cancer. J Clin Oncol 2004;22:3893-901.
    • (2004) J Clin Oncol , vol.22 , pp. 3893-3901
    • Keller, A.M.1    Mennel, R.G.2    Georgoulias, V.A.3
  • 19
    • 33847138943 scopus 로고    scopus 로고
    • Gemcitabine plus vinorelbine versus vinorelbine monotherapy in patients with metastatic breast cancer previously treated with anthracyclines and taxanes: Final results of the phase III Spanish breast cancer research group (GEICAM) trial
    • . Martin M, Ruiz A, Muñoz M, et al. Gemcitabine plus vinorelbine versus vinorelbine monotherapy in patients with metastatic breast cancer previously treated with anthracyclines and taxanes: final results of the phase III Spanish breast cancer research group (GEICAM) trial. Lancet Oncol 2007;8:219-25.
    • (2007) Lancet Oncol , vol.8 , pp. 219-225
    • Martin, M.1    Ruiz, A.2    Muñoz, M.3
  • 20
    • 36849071808 scopus 로고    scopus 로고
    • Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment
    • . Thomas ES, Gomez HL, Li RK, et al. Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment. J Clin Oncol 2007;25: 5210-17.
    • (2007) J Clin Oncol , vol.25 , pp. 5210-5217
    • Thomas, E.S.1    Gomez, H.L.2    Li, R.K.3
  • 21
    • 67049161336 scopus 로고    scopus 로고
    • Analysis of overall survival (OS) among patients (pts) with metastatic breast cancer (MBC) receiving either ixabepilone (I) plus capecitabine (C) or C alone: Results from two randomized phase III trials
    • Presented at the, Washington, DC, September 5-7
    • . Hortobagyi GN, Perez E, Vrdoljak E, et al. Analysis of overall survival (OS) among patients (pts) with metastatic breast cancer (MBC) receiving either ixabepilone (I) plus capecitabine (C) or C alone: results from two randomized phase III trials. Presented at the American Society of Clinical Oncology (ASCO) breast cancer symposium, Washington, DC, September 5-7, 2008.
    • (2008) American Society of Clinical Oncology (ASCO) breast cancer symposium
    • Hortobagyi, G.N.1    Perez, E.2    Vrdoljak, E.3
  • 22
    • 65349110371 scopus 로고    scopus 로고
    • Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: A German breast cancer group 26/breast cancer international group 03-05 study
    • . Von Minckwitz G, Du Bois A, Schmidt M, et al. Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: a German breast cancer group 26/breast cancer international group 03-05 study. J Clin Oncol 2009;27:1999-2006.
    • (2009) J Clin Oncol , vol.27 , pp. 1999-2006
    • Von Minckwitz, G.1    Du Bois, A.2    Schmidt, M.3
  • 23
    • 56549113680 scopus 로고    scopus 로고
    • A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: Updated efficacy and biomarker analyses
    • . Cameron D, Casey M, Press M, et al. A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses. Breast Cancer Res Treat 2008;112:533-43.
    • (2008) Breast Cancer Res Treat , vol.112 , pp. 533-543
    • Cameron, D.1    Casey, M.2    Press, M.3
  • 24
    • 54249153119 scopus 로고    scopus 로고
    • A randomized study of lapatinib alone or in combination with trastuzumab in heavily pretreated HER2+ metastatic breast cancer progressing on trastuzumab therapy [abstract]
    • abstract 1015
    • . O'Shaughnessy J, Blackwell KL, Burstein H, et al. A randomized study of lapatinib alone or in combination with trastuzumab in heavily pretreated HER2+ metastatic breast cancer progressing on trastuzumab therapy [abstract]. J Clin Oncol 2008;26(suppl):abstract 1015.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • O'Shaughnessy, J.1    Blackwell, K.L.2    Burstein, H.3
  • 25
    • 20044364346 scopus 로고    scopus 로고
    • Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer
    • . Miller KD, Chap LI, Holmes FA, et al. Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer. J Clin Oncol 2005;23:792-9.
    • (2005) J Clin Oncol , vol.23 , pp. 792-799
    • Miller, K.D.1    Chap, L.I.2    Holmes, F.A.3
  • 26
    • 0032949449 scopus 로고    scopus 로고
    • Prospective randomized trial of docetaxel versus mitomycin plus vinblastine in patients with metastatic breast cancer progressing despite previous anthracycline-containing chemotherapy: 304 study group
    • . Nabholtz JM, Senn HJ, Bezwoda WR, et al. Prospective randomized trial of docetaxel versus mitomycin plus vinblastine in patients with metastatic breast cancer progressing despite previous anthracycline-containing chemotherapy: 304 study group. J Clin Oncol 1999;17:1413-24.
    • (1999) J Clin Oncol , vol.17 , pp. 1413-1424
    • Nabholtz, J.M.1    Senn, H.J.2    Bezwoda, W.R.3
  • 27
    • 0037132372 scopus 로고    scopus 로고
    • Docetaxel vs 5-fluorouracil plus vinorelbine in metastatic breast cancer after anthracycline therapy failure
    • . Bonneterre J, Roche H, Monnier A, et al. Docetaxel vs 5-fluorouracil plus vinorelbine in metastatic breast cancer after anthracycline therapy failure. Br J Cancer 2002;87:1210-15.
    • (2002) Br J Cancer , vol.87 , pp. 1210-1215
    • Bonneterre, J.1    Roche, H.2    Monnier, A.3
  • 28
    • 42249083269 scopus 로고    scopus 로고
    • Weekly paclitaxel in the adjuvant treatment of breast cancer
    • . Sparano JA, Wang M, Martino S, et al. Weekly paclitaxel in the adjuvant treatment of breast cancer. N Engl J Med 2008;358: 1663-71.
    • (2008) N Engl J Med , vol.358 , pp. 1663-1671
    • Sparano, J.A.1    Wang, M.2    Martino, S.3
  • 29
    • 24944542869 scopus 로고    scopus 로고
    • Weekly paclitaxel improves pathologic complete remission in operable breast cancer when compared with paclitaxel once every 3 weeks
    • . Green MC, Buzdar AU, Smith T, et al. Weekly paclitaxel improves pathologic complete remission in operable breast cancer when compared with paclitaxel once every 3 weeks. J Clin Oncol 2005;23:5983-92.
    • (2005) J Clin Oncol , vol.23 , pp. 5983-5992
    • Green, M.C.1    Buzdar, A.U.2    Smith, T.3
  • 30
    • 43249115659 scopus 로고    scopus 로고
    • Randomized phase III trial of weekly compared with every-3-weeks paclitaxel for metastatic breast cancer, with trastuzumab for all HER-2 overexpressors and random assignment to trastuzumab or not in HER-2 nonoverexpressors: Final results of cancer and leukemia group B protocol 9840
    • . Seidman AD, Berry D, Cirrincione C, et al. Randomized phase III trial of weekly compared with every-3-weeks paclitaxel for metastatic breast cancer, with trastuzumab for all HER-2 overexpressors and random assignment to trastuzumab or not in HER-2 nonoverexpressors: final results of cancer and leukemia group B protocol 9840. J Clin Oncol 2008;26:1642-9.
    • (2008) J Clin Oncol , vol.26 , pp. 1642-1649
    • Seidman, A.D.1    Berry, D.2    Cirrincione, C.3
  • 31
    • 52449111361 scopus 로고    scopus 로고
    • Options for the treatment of patients with taxane-refractory metastatic breast cancer
    • . Overmoyer B. Options for the treatment of patients with taxane-refractory metastatic breast cancer. Clin Breast Cancer 2008;8(suppl 2):S61-70.
    • (2008) Clin Breast Cancer , vol.8 , Issue.SUPPL. 2
    • Overmoyer, B.1
  • 32
    • 0037096755 scopus 로고    scopus 로고
    • Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: Phase III trial results
    • . O'Shaughnessy J, Miles D, Vukelja S, et al. Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: phase III trial results. J Clin Oncol 2002;20:2812-23.
    • (2002) J Clin Oncol , vol.20 , pp. 2812-2823
    • O'Shaughnessy, J.1    Miles, D.2    Vukelja, S.3
  • 33
    • 43749090834 scopus 로고    scopus 로고
    • Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment [letter]
    • . Thomas ES. Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment [letter]. J Clin Oncol 2008;26:2223.
    • (2008) J Clin Oncol , vol.26 , pp. 2223
    • Thomas, E.S.1
  • 34
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
    • . Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001;344:783-92.
    • (2001) N Engl J Med , vol.344 , pp. 783-792
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3
  • 35
    • 37549040613 scopus 로고    scopus 로고
    • Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
    • . Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007;357:2666-76.
    • (2007) N Engl J Med , vol.357 , pp. 2666-2676
    • Miller, K.1    Wang, M.2    Gralow, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.